WordNet

a three-dimensional shape with six square or rectangular sides (同)cube
(computer science) a sector or group of sectors that function as the smallest data unit permitted; "since blocks are often defined as a single sector, the terms `block and `sector are sometimes used interchangeably"
support, secure, or raise with a block; "block a plate for printing"; "block the wheels of a car"
a solid piece of something (usually having flat rectangular sides); "the pyramids were built with large stone blocks"
housing in a large building that is divided into separate units; "there is a block of classrooms in the west wing"
a rectangular area in a city surrounded by streets and usually containing several buildings; "he lives in the next block" (同)city block
an inability to remember or think of something you normally can do; often caused by emotional tension; "I knew his name perfectly well but I had a temporary block" (同)mental_block
a number or quantity of related things dealt with as a unit; "he reserved a large block of seats"; "he held a large block of the companys stock"
interrupt the normal function of by means of anesthesia; "block a nerve"; "block a muscle"
run on a block system; "block trains"
shape by using a block; "Block a hat"; "block a garment"
shape into a block or blocks; "block the graphs so one can see the results clearly"
stamp or emboss a title or design on a book with a block; "block the book cover"
the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system
a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"
the 1st letter of the Roman alphabet (同)a
the blood group whose red cells carry the A antigen (同)type_A, group A
completely obstructed or closed off; "the storm was responsible for many blocked roads and bridges"; "the drain was plugged" (同)plugged
closed to traffic; "the repaving results in many blocked streets" (同)out of use

PrepTutorEJDIC

(木・石などの,通例平らな面のある)『かたまり』 / 《米》(四団を街路に囲まれた)『区画』,街区 / 街区の1辺の距離(一般に40メートル前後) / 《英》ブロック(アパート・事務所・商店などに区切られている大きな建物) / 『妨害物』,障害物(obstacle);(障害によって生じた)停滞,渋滞 / 台木,台(まないた・肉切り台・まき割り台・せり売り台・帽子の木型など);《the~》炭頭台 / (特にアメリカンフットボールで)ブロック(相手の選手の突進を阻止する) / 滑車(pulley) / (座席券・株券などの)一組《+『of』+『名』》 / 〈通路など〉'を'『ふさぐ』,〈通行・進行など〉'を'妨げる / 〈帽子など〉の型取りをする / (特にアメリカンフットボールで)〈相手選手の突進〉'を'ブロックする;(ボクシングで)〈相手のパンチ〉'を'ブロックする
carbonの化学記号
(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
answer / ampere

UpToDate Contents

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1. ブルガダ症候群および突然の心停止 brugada syndrome
2. 第2度房室ブロック：モビッツII型 second degree atrioventricular block mobitz type ii
3. 新生児ループス neonatal lupus
4. 先天性および後天性ＱＴ延長症候群の遺伝学 genetics of congenital and acquired long qt syndrome
5. 末梢神経ブロック：手技 peripheral nerve block techniques

English Journal

Sigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelope.

Tsai SY1, Chuang JY2, Tsai MS1, Wang XF3, Xi ZX3, Hung JJ4, Chang WC5, Bonci A6, Su TP7.
Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Nov 24;112(47):E6562-70. doi: 10.1073/pnas.1518894112. Epub 2015 Nov 9.
The sigma-1 receptor (Sig-1R) chaperone at the endoplasmic reticulum (ER) plays important roles in cellular regulation. Here we found a new function of Sig-1R, in that it translocates from the ER to the nuclear envelope (NE) to recruit chromatin-remodeling molecules and regulate the gene transcripti
PMID 26554014

Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation.

Guo Y1, Wang W2, Sun Y3, Ma C1, Wang X1, Wang X1, Liu P1, Shen S4, Li B5, Lin J1, Deng F4, Wang H6, Lou Z7.
Journal of virology.J Virol.2015 Nov 11;90(2):1048-61. doi: 10.1128/JVI.02523-15.
Hantaviruses, which belong to the genus Hantavirus in the family Bunyaviridae, infect mammals, including humans, causing either hemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS) in humans with high mortality. Hantavirus encodes a nucleocapsid protein (NP) to
PMID 26559827

Prognostic Significance of Premature Atrial Complexes Burden in Prediction of Long-Term Outcome.

Lin CY1, Lin YJ1, Chen YY2, Chang SL1, Lo LW1, Chao TF1, Chung FP1, Hu YF1, Chong E3, Cheng HM1, Tuan TC1, Liao JN1, Chiou CW1, Huang JL4, Chen SA1.
Journal of the American Heart Association.J Am Heart Assoc.2015 Aug 27;4(9):e002192. doi: 10.1161/JAHA.115.002192.
BACKGROUND: The prognostic significance of premature atrial complex (PAC) burden is not fully elucidated. We aimed to investigate the relationship between the burden of PACs and long-term outcome.METHODS AND RESULTS: We investigated the clinical characteristics of 5371 consecutive patients without a
PMID 26316525

Japanese Journal

NEUROPEPTIDE Y RESCUES AGING PHENOTYPE OF HUMAN HUTCHINSON-GILFORD PROGERIA SYNDROME FIBROBLASTS

Cavadas Claudia,Ferreira-Marques Marisa,Cortes Luisa,Valero Jorge,Pereira Dina,Pereira De Almeida Luis,Aveleira Celia A
日本薬理学会年会要旨集 WCP2018(0), OR11-1, 2018
… <p>Hutchinson-Gilford progeria syndrome (HGPS), a lethal rare genetic disorder, is characterized by premature aging. … HGPS is most commonly caused by a de novo point mutation (C608G) within the lamin A/C gene (LMNA), producing an abnormal lamin A protein termed progerin. …
NAID 130007899987