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1. 遺伝学の基礎概念：染色体と細胞分化basic genetics concepts chromosomes and cell division [show details]
… differences in distribution of other cellular contents: Symmetric divisions partition most of the cellular contents equally and create two relatively… Inhibitors of topoisomerase such as topotecan or irinotecan are used as anticancer therapies because they interfere with cell division.…
2. 上皮成長因子受容体（EGFR）阻害薬およびMEK阻害薬の投与に続発するざ瘡様発疹acneiform eruption secondary to epidermal growth factor receptor egfr and mek inhibitors [show details]
…and head and neck cancer (cetuximab) . The ability of EGFR inhibitors to block specific molecular pathways driving uncontrolled cellular division in cancer has resulted in a decreased incidence of serious …
3. 高齢者における免疫機能immune function in older adults [show details]
… Cellular senescence : Processes that occur as cells age, including division arrest,… include mammalian target of rapamycin (mTOR) inhibitors and statins. Agents that inhibit the mammalian target of rapamycin (mTOR) suppress…
4. 腎細胞癌の疫学、病理、および病因epidemiology pathology and pathogenesis of renal cell carcinoma [show details]
… The development of RCCs may also involve abnormalities in genes that control cell division.… Alterations in genes controlling cellular oxygen sensing such as VHL were common.… may underlie their robust responses to checkpoint inhibitor immunotherapy.…
5. 血管新生阻害剤の概要overview of angiogenesis inhibitors [show details]
… be inhibited by anti-VEGF and anti-VEGF receptor antibodies, soluble VEGF "decoy" receptors, and small molecule tyrosine kinase inhibitors (TKIs). Inhibition of VEGF signaling may inhibit tumor growth… by a capillary network that enables it to receive necessary nutrients and oxygen, and export its cellular products (eg, hormones, vasoactive materials, metabolic waste products). Following embryogenesis …

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