WordNet

of the transmission gear causing backward movement in a motor vehicle; "in reverse gear"
a relation of direct opposition; "we thought Sue was older than Bill but just the reverse was true" (同)contrary, opposite
the gears by which the motion of a machine can be reversed (同)reverse gear
the side of a coin or medal that does not bear the principal design (同)verso
(American football) a running play in which a back running in one direction hands the ball to a back running in the opposite direction
an unfortunate happening that hinders or impedes; something that is thwarting or frustrating (同)reversal, setback, blow, black_eye
move something or somebody around; usually over long distances
an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
transport commercially (同)send, ship
an animal sterol that is normally synthesized by the liver; the most abundant steroid in animal tissues (同)cholesterin
a lapel on a womans garment; turned back to show the reverse side (同)revere
turned inside out and resewn; "the reversed collar looked as good as new"

PrepTutorEJDIC

(位置・方向・順序などにおいて)『逆の』;裏側の』 / 逆に動かす(動く),バックの / 〈U〉《the reverse》(…の)『反対』,『逆』《+『of』+『名』(『wh』‐節)》》 / 〈U〉《the reverse》(貨幣・メダルなどの)『裏側』,(一般に)(…の)裏面《+『of』+『名』》 / 〈C〉(運命などの)逆転,不運 / 〈U〉後退[装置],逆転[装置] / …‘を'『逆にする』,反対にする;…‘を'裏返す / 〈機械など〉‘を'逆転させる,逆方向に動かす / 〈判決など〉‘を'取り消す,破棄する / (ダンスで)逆に回る / 〈機械などが〉逆方向に動く
(ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
コレステロール(胆汁・血液・神経組織などの脂肪性成分)
（フランス語）(えりの)裏出し,折り返し
逆にした,反対の,裏返のし;取り消された

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/07/14 10:04:52」(JST)

wiki en

Reverse cholesterol transport is a multi-step process resulting in the net movement of cholesterol from peripheral tissues back to the liver via the plasma.^[1]

Cholesterol from non-hepatic peripheral tissues is transferred to HDL by the ABCA1 (ATP-binding cassette transporter).^[2] Apolipoprotein A1 (ApoA-1), the major protein component of HDL, acts as an acceptor, and the phospholipid component of HDL acts as a sink for the mobilised cholesterol. The cholesterol is converted to cholesteryl esters by the enzyme LCAT (lecithin-cholesterol acyltransferase). The cholesteryl esters can be transferred, with the help of CETP (cholesterylester transfer protein) in exchange for triglycerides, to other lipoproteins (such as LDL and VLDL), and these lipoproteins can be taken up by secreting unesterified cholesterol into the bile or by converting cholesterol to bile acids.

Uptake of HDL₂ is mediated by hepatic lipase, a special form of lipoprotein lipase found only in the liver. Hepatic lipase activity is increased by androgens and decreased by estrogens, which may account for higher concentrations of HDL₂ in women.

References

^ Tall, AR (February 1998). "An overview of reverse cholesterol transport.". Eur. Heart J. 19 Suppl A: A31–5. doi:10.1093/eurheartj/19.Abstract_Supplement.1. PMID 9519340.
^ http://biochemistry.med.uoc.gr/photos/kardasis_research-07.gif in [1]

UpToDate Contents

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1. 冠動脈疾患または同等の冠動脈リスクを有する患者におけるコレステロール低下に関する
臨床試験 clinical trials of cholesterol lowering in patients with coronary heart disease or coronary risk equivalents
2. 冠動脈疾患の二次予防における脂質低下療法の強度 intensity of lipid lowering therapy in secondary prevention of coronary heart disease
3. フィブラート系薬剤による脂質低下 lipid lowering with fibric acid derivatives
4. スタチン系およびフィブラート系以外の薬剤による脂質低下 lipid lowering with drugs other than statins and fibrates
5. 脂質異常症に対するスクリーニングガイドライン screening guidelines for dyslipidemia

English Journal

Characterization of woodchuck apolipoprotein A-I: A new tool for drug delivery and identification of altered isoforms in the woodchuck chronic hepatitis model.

Fioravanti J, Gomar C, Medina-Echeverz J, Otano I, Benito A, Prieto J, Gonzalez-Aseguinolaza G, Berraondo P.SourceDivision of Hepatology and Gene Therapy, Center for Applied Medical Research, University of Navarra, Pamplona, Navarra, Spain.
Journal of medical virology.2011 Jul;83(7):1221-9. doi: 10.1002/jmv.22104. Epub 2011 Apr 22.
Apolipoprotein A-I (ApoA-I) is the major protein component of high density lipoprotein (HDL) particles in serum, and participates in the reverse transport of cholesterol from tissues to the liver for excretion. The natural HDL tropism to the liver and cancer cells has been used extensively to target
PMID 21520143

Japanese Journal

ABCA1/G1を介した糖・脂質代謝異常への介入--reverse cholesterol transportへの介入の意義 (特集糖・脂質代謝異常の新たな治療戦略)

綾織誠人,飯塚麻貴,池脇克則
糖尿病 54(3), 165-168, 2011-03
NAID 40018792981

Update on the Role of Endothelial Lipase in High-Density Lipoprotein Metabolism, Reverse Cholesterol Transport, and Atherosclerosis

YASUDA Tomoyuki,ISHIDA Tatsuro,RADER Daniel J.
Circulation journal : official journal of the Japanese Circulation Society 74(11), 2263-2270, 2010-10-25
… Similar to LPL and HL, EL regulates lipoprotein metabolism, mainly high-density lipoprotein (HDL) metabolism and HDL cholesterol (HDL-C) levels in humans and mice. … However, it has not been definitively established whether the effect of EL activity on HDL-C levels translates into effects on reverse cholesterol transport or atherosclerosis. …
NAID 10026972324