WordNet

travel or traverse (a distance); "This car does 150 miles per hour"; "We did 6 miles on our hike every day"
the syllable naming the first (tonic) note of any major scale in solmization (同)doh, ut
proceed or get along; "How is she doing in her new job?"; "How are you making out in graduate school?"; "Hes come a long way" (同)fare, make_out, come, get along
create or design, often in a certain way; "Do my room in blue"; "I did this piece in wood to express my love for the forest" (同)make
carry on or function; "We could do with a little more help around here" (同)manage
get (something) done; "I did my job" (同)perform
primarily temporal sense; being or indicating a relatively great or greater than average duration or passage of time or a duration as specified; "a long life"; "a long boring speech"; "a long time"; "a long friendship"; "a long game"; "long ago"; "an hour long"
(of speech sounds or syllables) of relatively long duration; "the English vowel sounds in `bate, `beat, `bite, `boat, `boot are long"
for an extended distance
for an extended time or at a distant time; "a promotion long overdue"; "something long hoped for"; "his name has long been forgotten"; "talked all night long"; "how long will you be gone?"; "arrived long before he was expected"; "it is long after your bedtime"
having or being more than normal or necessary:"long on brains"; "in long supply"
holding securities or commodities in expectation of a rise in prices; "is long on coffee"; "a long position in gold"
involving substantial risk; "long odds"
of relatively great height; "a race of long gaunt men"- Sherwood Anderson; "looked out the long French windows"
primarily spatial sense; of relatively great or greater than average spatial extension or extension as specified; "a long road"; "a long distance"; "contained many long words"; "ten miles long"
unrefined in character; "low comedy"
an air mass of lower pressure; often brings precipitation; "a low moved in over night bringing sleet and snow" (同)depression
a low level or position or degree; "the stock market fell to a new low"
used of sounds and voices; low in pitch or frequency (同)low-pitched
very low in volume; "a low murmur"; "the low-toned murmur of the surf" (同)low-toned
in a low position; near the ground; "the branches hung low"
less than normal in degree or intensity or amount; "low prices"; "the reservoir is low"
literal meanings; being at or having a relatively small elevation or upward extension; "low ceilings"; "low clouds"; "low hills"; "the sun is low"; "low furniture"; "a low bow"
a method of tending to or managing the affairs of a some group of people (especially the groups business affairs) (同)disposal
the act of administering medication (同)giving medication
the act of meting out justice according to the law (同)judicature
the persons (or committees or departments etc.) who make up a body for the purpose of administering something; "he claims that the present administration is corrupt"; "the governance of an association is responsible to its members"; "he quickly became rec (同)governance, governing body, establishment, brass, organization, organisation
name formally or designate with a term
the end of gestation or point at which birth is imminent; "a healthy baby born at full term" (同)full term
a limited period of time; "a prison term"; "he left school before the end of term"
a word or expression used for some particular thing; "he learned many medical terms"
any distinct quantity contained in a polynomial; "the general term of an algebraic equation of the n-th degree"
one of the substantive phrases in a logical proposition; "the major term of a syllogism must occur twice"

PrepTutorEJDIC

《疑問文・否定文を作る》 / 《否定命令文を作る》 / 《助動詞とbe動詞のどちらも含まない文に用いて付加疑問を作る》 / 《強意語として》 / 《文》《助動詞とbe動詞のどちらも含まない文に用いて倒置文を作る》 / 《あいづちを打つ場合に》 / 《先行する動詞またはそれを含む述部の代用》 / 《so,nor,neitherで始まる簡略文で》 / …‘を'『する』,行う,果たす / 《通例have done,時にbe doneの形で》…‘を'『終える』,済ませる / …‘を'作る,作り出す / …‘を'『処理する』,整える,片付ける / 〈学課〉‘を'『勉強する』,専攻する / 〈利益・害など〉‘を'与える,もたらす / 〈人〉‘に'『役立つ』,用が足りる(serve) / …の速度で進む,距離を行く / …‘を'見物する / 〈劇〉‘を'上演する;…‘の'役を演じる / …の役目(仕事)をする / 《おもに英》…‘を'だます,かつぐ / 《話》…をへとへとにさせる / 『する』;活動する / 《通例have done,時にbe doneの形で》(…を)『終える』,済ます《+『with』+『名』》 / 〈事が〉『運ぶ』;〈人が〉暮らしていく,健康である / 〈物が〉(…に)『間に合う』,十分である;〈人が〉(…に)役に立つ,向く《+『for』+『名』》 / 《複数形で》すべきこと / 〈C〉《おもに英》大宴会,大パーティー / 〈C〉《英話》詐欺,ぺてん
ド(全音階の第1音)
(距離・物の長さが)『長い』 / (時間が)『長い』,長く続く / 《時間・距離などを表離などを表す語を伴って》長さが…の / 『長々しい』,あきあきする / (数量が標準よりも)『多い』,長い / (人が)やせてひょろ長い / 長く,長い間,久しく / …じゅう / ずっと(前に,後に) / 長い間
『熱望する』
(高さ・位置が)『低い』,低い所にある / (価格・数量・程度などが)『低い』,少ない / (身分・地位などが)『低い』,卑しい / (人格・行為などが)『卑しい』,下劣な,下品な / 《補語にのみ用いて》(体が)『弱った』;元気のない,憂うつな / (供給が)不十分な;(…が)乏しい《+『in』(『on』)+『名』》 / (音・声が)低い,小さい / (生物が)下等な / 『低く』,低い所に / (価格・程度などが)『安く』,低く / 低い声(調子)で;静かに / 最低点,最低水準
(牛の)モーという鳴き声 / (牛が)モーと鳴く
〈U〉『行政』,統治 / 〈U〉『管理』,経営 / 〈C〉行政機関(省,庁,局など);《the A-》《米》連邦政府(《英》the Government) / 《総称して》(大学・団体などの)管理者側,当局者,教務部 / 〈U〉(裁き・処罰・法冷・儀式などの)執行,施行
〈C〉『専門用語』,術語 / 〈C〉(一般に)語[句],言葉 / 《複数形で》言い道,言飯遣い / 〈C〉『期間』 / 〈C〉〈U〉『学期』 / 《複数形で》(人との)間柄,仲《+with+名》 / 《複数形で》(協定などの)『条件』;要求額,値段 / 〈C〉(数式で)項 / 《term+名〈目〉+名(形)〈補〉》(…と)…‘を'名づける,呼ぶ

UpToDate Contents

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1. マクロライド系剤、アミノグリコシド、テトラサイクリン、クリンダマイシン、およびメトロニダゾールに対する過敏反応 hypersensitivity reactions to macrolides aminoglycosides tetracyclines clindamycin and metronidazole
2. アジスロマイシン、クラリスロマイシン、およびテリスロマイシン azithromycin clarithromycin and telithromycin
3. 成人における気管支拡張症の治療 treatment of bronchiectasis in adults
4. びまん性汎細気管支炎 diffuse panbronchiolitis
5. 早期梅毒の病因、臨床症状、および治療 pathogenesis clinical manifestations and treatment of early syphilis

English Journal

Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium.

Tojima I1, Shimizu S2, Ogawa T2, Kouzaki H2, Omura S3, Sunazuka T3, Shimizu T2.
Auris, nasus, larynx.Auris Nasus Larynx.2015 Aug;42(4):332-6. doi: 10.1016/j.anl.2015.02.003. Epub 2015 Mar 10.
OBJECTIVE: Low-dose, long-term use of 14-membered macrolides is effective for treatment of patients with chronic airway inflammation such as diffuse panbronchiolitis or chronic rhinosinusitis. However, long-term use of macrolides can promote the growth of drug-resistant bacteria, and the development
PMID 25769240

Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis.

Haxel BR1, Clemens M, Karaiskaki N, Dippold U, Kettern L, Mann WJ.
The Laryngoscope.Laryngoscope.2015 May;125(5):1048-55. doi: 10.1002/lary.25052. Epub 2014 Nov 25.
OBJECTIVES/HYPOTHESIS: The efficacy of macrolides in chronic rhinosinusitis (CRS) is still under controversy. To date, only two double-blind, placebo-controlled studies have been published with differing results. None of these studies investigated the possible benefit of macrolides in the postoperat
PMID 25425539

Effects of Preoperative Clarithromycin Administration in Patients with Nasal Polyposis.

Perić A1, Baletić N2, Milojević M2, Sotirović J2, Živić L3, Perić AV4, Vojvodić D5.
The West Indian medical journal.West Indian Med J.2015 Mar 20;63(7). doi: 10.7727/wimj. 2013.313. [Epub ahead of print]
OBJECTIVE: In the recent years, various investigators have shown considerable interest in the use of macrolide antibiotics for treatment of chronic rhinosinusitis and nasal polyposis. The aim of this study was to evaluate the clinical effects of pre-operative long-term low-dose clarithromycin admini
PMID 25867579

Japanese Journal

マクロライド系抗菌薬の処方実態に基づく慢性炎症性疾患に対する少量長期投与療法の有効性に関する再検証 : 常用量投与との比較

薬局薬学 6(2), 157-166, 2014
NAID 40020235734

The Successful Management of Respiratory Complications With Long-Term, Low-Dose Macrolide Administration in Pediatric Heart Transplant Recipients

International Heart Journal 55(6), 560-563, 2014
NAID 130004694354

A Case of Refractory Chronic Respiratory Tract Infection due to Pseudomonas aeruginosa Successfully Controlled by Combination of Clarithromycin and Azithromycin