WordNet

a silvery soft waxy metallic element of the alkali metal group; occurs abundantly in natural compounds (especially in salt water); burns with a yellow flame and reacts violently in water; occurs in sea water and in the mineral halite (rock salt) (同)Na, atomic number 11

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1. 関節内および軟部組織注射：注射剤の種類および投与頻度intraarticular and soft tissue injections what agents to inject and how frequently [show details]
…acute calcium pyrophosphate crystal arthritis (pseudogout) have occurred two or three days after hyaluronate injection . Platelet-rich plasma (PRP) injections have been used in an attempt to treat various…
2. 注入可能軟部組織充填剤：非永久性充填剤injectable soft tissue fillers temporary agents [show details]
3. 変形性膝関節症のマネージメントmanagement of knee osteoarthritis [show details]
4. シェーグレン症候群によるドライアイの治療：一般原則および初回治療treatment of dry eye in sjogrens syndrome general principles and initial therapy [show details]
…One compared hyaluronate and carboxymethylcellulose eyedrops, showing that both improved symptoms and corneal surface findings . A different trial demonstrated greater benefit from hyaluronate compared with …
5. 中等度から重度の変形性膝関節症のマネージメントmanagement of moderate to severe knee osteoarthritis [show details]

Carboxymethyl chitosan-mediated synthesis of hyaluronic acid-targeted graphene oxide for cancer drug delivery.

Yang H1, Bremner DH2, Tao L3, Li H4, Hu J5, Zhu L6.
Carbohydrate polymers.Carbohydr Polym.2016 Jan 1;135:72-8. doi: 10.1016/j.carbpol.2015.08.058. Epub 2015 Aug 22.
In order to enhance the efficiency and specificity of anticancer drug delivery and realize intelligently controlled release, a new drug carrier was developed. Graphene oxide (GO) was first modified with carboxymethyl chitosan (CMC), followed by conjugation of hyaluronic acid (HA) and fluorescein iso
PMID 26453853

Evaluation of cystamine-modified hyaluronic acid/chitosan polyplex as retinal gene vector.

Oliveira AV1, Marcelo A2, Rosa da Costa AM3, Silva GA4.
Materials science & engineering. C, Materials for biological applications.Mater Sci Eng C Mater Biol Appl.2016 Jan 1;58:264-72. doi: 10.1016/j.msec.2015.08.047. Epub 2015 Aug 28.
PURPOSE: A successful gene therapy approach can prevent or treat congenital and acquired diseases. However, there is still no ideal non-viral vector for gene delivery in a safe and timely manner. In this report the anionic polymer hyaluronic acid (HA) was investigated as a potential vector for gene
PMID 26478310

Delivery of liquorice extract by liposomes and hyalurosomes to protect the skin against oxidative stress injuries.

Castangia I1, Caddeo C1, Manca ML2, Casu L1, Latorre AC3, Díez-Sales O4, Ruiz-Saurí A5, Bacchetta G1, Fadda AM1, Manconi M1.
Carbohydrate polymers.Carbohydr Polym.2015 Dec 10;134:657-63. doi: 10.1016/j.carbpol.2015.08.037. Epub 2015 Aug 20.
Liquorice extract, obtained by percolation in ethanol of Glycyrrhiza glabra L. roots, was incorporated in liposomes and hyalurosomes, new phospholipid-sodium hyaluronate vesicles, and their protective effect against oxidative stress skin damages was probed. As a comparison, raw glycyrrhizin was also
PMID 26428169

清野慧至,髙田幸尚,雑賀司珠也
薬学雑誌 141(1), 35-39, 2021
… Sodium hyaluronate eyedrops are prescribed for corneal epithelial disorders such as superficial punctate keratitis associated with dry eye. … Prescribable concentrations of sodium hyaluronate in Japan are 0.1% or 0.3%, and the 0.3% formulation does not contain BAC. …
NAID 130007964828

石井聖弥,吉岡敬二,森田大輔
薬学雑誌 140(9), 1141-1150, 2020
… We have reported that the novel sodium hyaluronate derivative chemically linked with diclofenac (DF), diclofenac etalhyaluronate (SI-613), exerted a potent and long-lasting analgesic effect in experimental arthritis models. …
NAID 130007893761

日出間るり,鈴木洋
混相流 34(2), 302-309, 2020
… <p>In this study, the effects of polymer flexibility and entanglement on elastic instability were investigated by observing sodium hyaluronate (Hyaluronic Acid Sodium salt, Na-HA) solution in planar abrupt contraction-expansion microchannels. …
NAID 130007872616