WordNet
- mark with lines; "sorrow had lined his face"
- a length (straight or curved) without breadth or thickness; the trace of a moving point
- a single frequency (or very narrow band) of radiation in a spectrum
- reinforce with fabric; "lined books are more enduring"
- a particular kind of product or merchandise; "a nice line of shoes" (同)product line, line of products, line of merchandise, business line, line of business
- the road consisting of railroad track and roadbed (同)railway line, rail line
- a commercial organization serving as a common carrier
- acting in conformity; "in line with"; "he got out of line"; "toe the line"
- something (as a cord or rope) that is long and thin and flexible; "a washing line"
- a conceptual separation or distinction; "there is a narrow line between sanity and insanity" (同)dividing_line, demarcation, contrast
- a formation of people or things one behind another; "the line stretched clear around the corner"; "you must wait in a long line at the checkout counter"
- a formation of people or things one beside another; "the line of soldiers advanced with their bayonets fixed"; "they were arrayed in line of battle"; "the cast stood in line for the curtain call"
- a fortified position (especially one marking the most forward position of troops); "they attacked the enemys line"
- a mark that is long relative to its width; "He drew a line on the chart"
- a spatial location defined by a real or imaginary unidimensional extent
- in games or sports; a mark indicating positions or bounds of the playing area
- persuasive but insincere talk that is usually intended to deceive or impress; "`let me show you my etchings is a rather worn line"; "he has a smooth line but I didnt fall for it"; "that salesman must have practiced his fast line of talk"
- text consisting of a row of words written across a page or computer screen; "the letter consisted of three short lines"; "there are six lines in every stanza"
- be in line with; form a line along; "trees line the riverbank" (同)run along
- cover the interior of; "line the gloves"; "line a chimney"
- fill plentifully; "line ones pockets"
- providing something with a surface of a different material (同)facing
- a protective covering that protects an inside surface (同)liner
- the act of attaching an inside lining (to a garment or curtain etc.)
- a small apparently simple structure (as a fertilized egg) from which new tissue can develop into a complete organism
- (genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism (同)genetic mutation, chromosomal_mutation
- a change or alteration in form or qualities
PrepTutorEJDIC
- 『線』,筋,けい / (色・縫い目などの)『線』,しま;(顔・手などの)しわ(wrinkle) / (物・人の)『列』,行列(row) / 『綱』,糸,針金 / 電線,電話線,電信線 / (文章の)『行』;(詩の)『行』 / 《しばしばa~》《話》『短い手紙』(note) / 《複数形で》輪郭,外形(outline) / 境界線(boundary);限界,限度(limit) / (鉄道・バスなどの)路線;航路,空路 / 《複数形で》せりふ / 進路,道順(course);(考えなどの)筋道,方針 / 《しばしばone's~》(活動の)分野,方面;特意 / 家系,血統,血筋 / 在庫商品,仕入れ品 / 導管,パイプライン / 《しばしば複数形で》戦線,防御線 / …‘に'『線を引く』,筋(しま,しわ)をつける / …‘に'『沿って並ぶ;』(…を)…‘に'沿って並べる《+『名』+『with』+『名』》
- (材料で)〈着物など〉‘に'裏を付ける《+『名』『with』+『名』》 / (…で)…‘を'満たす,(…を)…‘に'詰め込む《+『名』+『with』+『名』》
- 〈U〉(服などの)裏張り,裏塗り / 〈U〉裏地,裏材
- 細菌,ばい菌 / (植物の)胚(はい),幼芽;(動物の)卵子 / 原因;(発達の)初期
- 変化,俸転 / (生物の)突然変異;その変種
UpToDate Contents
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English Journal
- Risk of Serous Endometrial Carcinoma in Women With Pathogenic BRCA1/2 Variant After Risk-Reducing Salpingo-Oophorectomy.
- Saule C1, Mouret-Fourme E1, Briaux A1, Becette V1, Rouzier R1, Houdayer C1, Stoppa-Lyonnet D1.
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- PMID 28954295
- Germline mutations in DNA repair genes predispose asbestos-exposed patients to malignant pleural mesothelioma.
- Betti M1, Casalone E2, Ferrante D3, Aspesi A1, Morleo G1, Biasi A1, Sculco M1, Mancuso G4, Guarrera S2, Righi L5, Grosso F6, Libener R7, Pavesi M8, Mariani N9, Casadio C10, Boldorini R4, Mirabelli D11, Pasini B12, Magnani C13, Matullo G12, Dianzani I14.
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- Agrin-LRP4-MuSK signaling as a therapeutic target for myasthenia gravis and other neuromuscular disorders.
- Ohno K1, Ohkawara B1, Ito M1.
- Expert opinion on therapeutic targets.Expert Opin Ther Targets.2017 Oct;21(10):949-958. doi: 10.1080/14728222.2017.1369960. Epub 2017 Aug 24.
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Japanese Journal
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- 萩原 弘一
- 日本呼吸器学会誌 = Annals of the Japanese Respiratory Society 3(1), 9-15, 2014-01-10
- NAID 40019962001
- Stage Ⅳ結腸癌合併家族性大腸腺腫症に認めた甲状腺多発乳頭癌の１例
- 中井 麻木,石田 文孝,大西 清,大澤 智徳,横山 勝,隈元 謙介,石橋 敬一郎,石田 秀行
- 日本外科系連合学会誌 39(2), 175-180, 2014
- 家族性大腸腺腫症に合併した多発甲状腺癌の１例について，遺伝子検査の結果とともに報告する．症例は38歳，女性．２年前に家族性大腸腺腫症，横行結腸癌，多発肝転移，腹膜播腫，甲状腺癌と診断され横行結腸癌（Stage Ⅳ）に対し，mFOLFOX6療法を受けたところ，多発肝転移が完全消失したため，結腸全摘・回腸直腸吻合術を施行した．結腸切除後２年後に甲状腺癌（左葉に２か所，右葉に１か所）に対し，甲状腺全摘術 …
- NAID 130005067629
- SMAD4遺伝子変異が診断に有用であった胃限局型若年性ポリポーシスの1例
- 永末 裕友,小西 毅,新井 正美,瀧 景子,上野 雅資,福長 洋介,長山 聡,藤本 佳也,秋吉 高志,山本 智理子
- 日本消化器外科学会雑誌 46(5), 325-333, 2013
- … したが，末梢血DNAの遺伝子診断を施行したところ，若年性ポリポーシス（以下，JPsと略記）関連遺伝子であるSMAD4遺伝子変異を認め，胃限局型JPsの最終診断に至った．さらに，本症例は，世界的にも過去に報告のないnovel mutationを有していた．本邦ではJPsにおけるSMAD4遺伝子変異の報告はいまだ少ないが，同遺伝子の変異検索は診断確定に有用であるため，胃限局型ポリポーシスの鑑別診断に際し念頭におく必要がある． …
- NAID 130004560948
Related Pictures
★リンクテーブル★
| リンク元 | 「germline mutation」「生殖細胞系列変異」 |
| 関連記事 | 「LINE」「line」「germ」「germ line」「lining」 |
「germline mutation」
「生殖細胞系列変異」
「LINE」
- 日
- 長い散在反復配列、長散在型反復配列、長い散在性反復配列、ライン、広範囲散在反復配列
- 英
- long interspersed nuclear element, long interspersed nucleotide element, long interspersed element, long interspersed repetitive elements, LINEs, long interspersed repeat sequences
- 関
- レトロトランスポゾン
- Long interspersed nuclear elements[8] are a group of genetic elements that are found in large numbers in eukaryotic genomes. They are transcribed (or are the evolutionary remains of what was once transcribed) to an RNA using an RNA polymerase II promoter that resides inside the LINE. LINEs code for the enzyme reverse transcriptase, and many LINEs also code for an endonuclease (e.g. RNase H). The reverse transcriptase has a higher specificity for the LINE RNA than other RNA, and makes a DNA copy of the RNA that can be integrated into the genome at a new site.
- The 5' UTR contains the promoter sequence, while the 3' UTR contains a polyadenylation signal (AATAAA) and a poly-A tail.[10] Because LINEs move by copying themselves (instead of moving, like transposons do), they enlarge the genome. The human genome, for example, contains about 20,000-40,000 LINEs, which is roughly 21% of the genome.
「line」
- n.
- v.
- 裏打ちする
「germ」
- n.
- 関
- anlage、anlagen、embryo、embryonic、germinal、microbe、microbial、microorganism、placode、primordia、primordium
「germ line」
- 生殖系列、生殖系の
「lining」
- n.