同: LINEs

WordNet

primarily temporal sense; being or indicating a relatively great or greater than average duration or passage of time or a duration as specified; "a long life"; "a long boring speech"; "a long time"; "a long friendship"; "a long game"; "long ago"; "an hour long"
(of speech sounds or syllables) of relatively long duration; "the English vowel sounds in `bate, `beat, `bite, `boat, `boot are long"
for an extended distance
for an extended time or at a distant time; "a promotion long overdue"; "something long hoped for"; "his name has long been forgotten"; "talked all night long"; "how long will you be gone?"; "arrived long before he was expected"; "it is long after your bedtime"
having or being more than normal or necessary:"long on brains"; "in long supply"
holding securities or commodities in expectation of a rise in prices; "is long on coffee"; "a long position in gold"
involving substantial risk; "long odds"
of relatively great height; "a race of long gaunt men"- Sherwood Anderson; "looked out the long French windows"
primarily spatial sense; of relatively great or greater than average spatial extension or extension as specified; "a long road"; "a long distance"; "contained many long words"; "ten miles long"
determine the order of constituents in; "They sequenced the human genome"
a following of one thing after another in time; "the doctor saw a sequence of patients" (同)chronological sequence, succession, successiveness, chronological succession
film consisting of a succession of related shots that develop a given subject in a movie (同)episode
serial arrangement in which things follow in logical order or a recurrent pattern; "the sequence of names was alphabetical"; "he invented a technique to determine the sequence of base pairs in DNA"
several repetitions of a melodic phrase in different keys
arrange in a sequence
do over; "They would like to take it over again" (同)take_over
an event that repeats; "the events today were a repeat of yesterdays" (同)repetition
to say again or imitate; "followers echoing the cries of their leaders" (同)echo
to say, state, or perform again; "She kept reiterating her request" (同)reiterate, ingeminate, iterate, restate, retell
place at intervals in or among; "intersperse exclamation marks in the text"
introduce ones writing or speech with certain expressions (同)interlard
prolonged unfulfilled desire or need (同)yearning, hungriness

PrepTutorEJDIC

(距離・物の長さが)『長い』 / (時間が)『長い』,長く続く / 《時間・距離などを表離などを表す語を伴って》長さが…の / 『長々しい』,あきあきする / (数量が標準よりも)『多い』,長い / (人が)やせてひょろ長い / 長く,長い間,久しく / …じゅう / ずっと(前に,後に) / 長い間
『熱望する』
〈U〉〈C〉(時間の上の,また因果関係のつながりによる)『連続』,続き / 〈C〉《a~》(…の)一連のもの《+『of』+『名』》 / 〈U〉(起こる)『順序』(order),筋道 / 〈C〉(…に対する)結果《+『to』+『名』》
〈自分がすでに一度言ったこと)‘を'『繰り返して言う』 / 〈他人の言ったこと〉‘を'おうむ返しに言う;…‘を'他の人に繰り返して言う / …‘を'『暗記して言う』,暗唱する / …‘を'繰り返して行う(do again) / (食べたあとで)〈食物の〉味が残る / 〈小数が〉循環する / 繰り返すこと,反復すること / 繰り返されるもの,(公演の)再演;(番組の)再放送 / 反復楽節;反復記号(∥: :∥)
(…の間に)…‘を'散らばせる,まき散らす《+『名』+『among』(『between』)+『名』》 / 《通例受動態で》(他のものを散りばめて)…‘に'変化を与える;(他のものを)…‘に'散りばめる《+『名』+『with』+『名』》
『あこがれ』,熱望 / (目の表情などが)あこがれの,熱望している

UpToDate Contents

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1. 先天性および後天性ＱＴ延長症候群の遺伝学 genetics of congenital and acquired long qt syndrome
2. 帝王切開の再施行 repeat cesarean delivery
3. 脊髄小脳変性症 the spinocerebellar ataxias
4. 前立腺生検 prostate biopsy
5. 先天性ＱＴ延長症候群の診断 diagnosis of congenital long qt syndrome

English Journal

LINE-1-Derived Poly(A) Microsatellites Undergo Rapid Shortening and Create Somatic and Germline Mosaicism in Mice.

Grandi FC, Rosser JM, An W.SourceSchool of Molecular Biosciences and Center for Reproductive Biology, Washington State University.
Molecular biology and evolution.Mol Biol Evol.2013 Mar;30(3):503-12. doi: 10.1093/molbev/mss251. Epub 2012 Nov 2.
Interspersed and tandem repeat sequences comprise the bulk of mammalian genomes. Interspersed repeats result from successive replication by transposable elements, such as Alu and long interspersed element type 1 (L1). Microsatellites are tandem repeats of 1-6 base pairs, among which poly(A) microsat
PMID 23125228

Analysis of circulating DNA distribution in pregnant and nonpregnant dairy cows.

Mayer J, Beck J, Soller JT, Wemheuer W, Schütz E, Brenig B.SourceInstitute of Veterinary Medicine, University of Göttingen, Göttingen, Germany.
Biology of reproduction.Biol Reprod.2013 Feb 7;88(2):29. doi: 10.1095/biolreprod.112.103168. Print 2013.
Circulating nucleic acids (CNAs) are free-floating, cell-free DNA and RNA molecules in the circulation of healthy and diseased humans and animals. The aim of this study was to identify differences in CNA distribution in serum samples from multiparous pregnant (n = 24) and nonpregnant (n = 16) dairy
PMID 23255334

Molecular reconstruction of extinct LINE-1 elements and their interaction with nonautonomous elements.

Wagstaff BJ, Kroutter EN, Derbes RS, Belancio VP, Roy-Engel AM.SourceDepartment of Epidemiology and Tulane Cancer Center, Tulane University, New Orleans, LA, USA.
Molecular biology and evolution.Mol Biol Evol.2013 Jan;30(1):88-99. doi: 10.1093/molbev/mss202. Epub 2012 Aug 23.
Non-long terminal repeat retroelements continue to impact the human genome through cis-activity of long interspersed element-1 (LINE-1 or L1) and trans-mobilization of Alu. Current activity is dominated by modern subfamilies of these elements, leaving behind an evolutionary graveyard of extinct Alu
PMID 22918960

「LINE」

　　[★]

日: 長い散在反復配列、長散在型反復配列、長い散在性反復配列、ライン、広範囲散在反復配列
英: long interspersed nuclear element, long interspersed nucleotide element, long interspersed element, long interspersed repetitive elements, LINEs, long interspersed repeat sequences
関: レトロトランスポゾン

quoted from http://en.wikipedia.org/wiki/Long_interspersed_nucleotide_elements#LINEs

Long interspersed nuclear elements[8] are a group of genetic elements that are found in large numbers in eukaryotic genomes. They are transcribed (or are the evolutionary remains of what was once transcribed) to an RNA using an RNA polymerase II promoter that resides inside the LINE. LINEs code for the enzyme reverse transcriptase, and many LINEs also code for an endonuclease (e.g. RNase H). The reverse transcriptase has a higher specificity for the LINE RNA than other RNA, and makes a DNA copy of the RNA that can be integrated into the genome at a new site.

The 5' UTR contains the promoter sequence, while the 3' UTR contains a polyadenylation signal (AATAAA) and a poly-A tail.[10] Because LINEs move by copying themselves (instead of moving, like transposons do), they enlarge the genome. The human genome, for example, contains about 20,000-40,000 LINEs, which is roughly 21% of the genome.