カフェオレ斑
WordNet
- mark with a spot or spots so as to allow easy recognition; "spot the areas that one should clearly identify"
- a small piece or quantity of something; "a spot of tea"; "a bit of paper"; "a bit of lint"; "I gave him a bit of my mind" (同)bit
- a small contrasting part of something; "a bald spot"; "a leopards spots"; "a patch of clouds"; "patches of thin ice"; "a fleck of red" (同)speckle, dapple, patch, fleck, maculation
- a business establishment for entertainment; "night spot"
- a playing card with a specified number of pips on it to indicate its value; "an eight-spot"
- a mark on a die or on a playing card (shape depending on the suit) (同)pip
- a section of an entertainment that is assigned to a specific performer or performance; "they changed his spot on the program"
- a short section or illustration (as between radio or tv programs or in a magazine) that is often used for advertising
- make a spot or mark onto; "The wine spotted the tablecloth" (同)fleck, blob, blot
- detect with the senses; "The fleeing convicts were picked out of the darkness by the watchful prison guards"; "I cant make out the faces in this photograph" (同)recognize, recognise, distinguish, discern, pick out, make_out, tell apart
- become spotted; "This dress spots quickly"
- a small restaurant where drinks and snacks are sold (同)coffeehouse, coffee_shop, coffee_bar
- the syllable naming the sixth (submediant) note of a major or minor scale in solmization (同)lah
PrepTutorEJDIC
- 『斑点』(はんてん),まだら,ぶち;(太陽の)黒点 / 『しみ』,よごれ;吹出物,にきび / (…に対する)汚名,汚点《+『on』+『名』》 / 『場所』,地点;部分,箇所 / (順序・組織における)位置;立場,おかれた状況 / 《a spot》《英話》(…の)少量,ちょっぴり(の…);(…の)1杯《+『of』+『名』》 / (ラジオ・テレビ番組の)構成区分 / …‘を'『しみで汚す』,‘に'汚れをつける;…‘に'斑点(はんてん)をつける,‘を'まだら(ぶち)にする;( …で)…‘に'しみ(斑点)をつける《+『名』+『with』+『名』》 / 〈人格・名声など〉‘を'汚す,傷つける / (特定の場所に)…‘を'置く,配置する / …‘を'見つける;(…だと)…‘を'見抜く《+『名』+『as』(『for』)+『名』》 / 〈インクなどが〉『しみになる』;〈布などが〉汚れる / 即座になされる,即時払いの(引き渡しの) / 現場での,現地の / (ラジオ・テレビで)番組の間に放送される / ちょうど,ぴったり(exactly)
- 〈C〉『喫茶店』(coffeehouse),小レストラン);《英》(酒類を出さない)『軽食堂』 / 〈C〉バー,キャバレー,ナイトクラブ
- ラ(全音階の第6音)
- goldの化学記号
- circa
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/09/19 02:42:40」(JST)
[Wiki en表示]
Café au lait spot |
Classification and external resources |
A café au lait spot on a patient's left cheek.
|
ICD-10 |
L81.3 |
ICD-9 |
709.09 |
DiseasesDB |
16118 |
eMedicine |
ped/2754 |
MeSH |
D019080 |
See also: List of conditions associated with café au lait macules
Café au lait spots or café au lait macules are pigmented birthmarks.[1] The name café au lait is French for "coffee with milk" and refers to their light-brown color. They are also called "giraffe spots" or "coast of Maine spots".[2]
Contents
- 1 Etiology
- 2 Diagnosis
- 3 Prognosis
- 4 Treatment
- 5 See also
- 6 References
- 7 External links
Etiology
Neurofibromatosis type I café au lait spot
Café au lait spots can arise from diverse and unrelated causes:[3][4]
- Having six or more café au lait spots greater than 5 mm in diameter before puberty, or greater than 15 mm in diameter after puberty, is a diagnostic feature of neurofibromatosis type I, but other features are required to diagnose NF-1.
- Familial multiple café au lait spots have been observed without NF-1 diagnosis.[5]
- They can be caused by vitiligo in the rare McCune–Albright syndrome.[6]
- Legius syndrome
- Tuberous sclerosis
- Fanconi anemia, a rare genetic disease.
- Idiopathic
- Ataxia telangiectasia
- Basal cell nevus syndrome
- Benign congenital skin lesion
- Bloom syndrome
- Chediak Higashi syndrome
- Congenital naevus
- Gaucher disease
- Hunter syndrome
- Maffucci syndrome
- Multiple mucosal neuroma syndrome
- Noonan syndrome
- Pulmonary Stenosis
- Silver–Russell syndrome
- Watson syndrome
- Wiskott–Aldrich syndrome
Diagnosis
Diagnosis is visual with measurement of spot size and count of number of spots having clinical significance for diagnosis of associated disorders such as Neurofibromatosis type I. Usually, more than 6 spots more than 3 cm in diameter indicates NF1.
Prognosis
Café au lait spots are benign and do not cause any ailment themselves.
Treatment
They can be treated with lasers.[7]
See also
- Birthmark
- Nevus
- List of cutaneous conditions
- List of conditions associated with café au lait macules
References
- ^ Plensdorf S, Martinez J (January 2009). "Common pigmentation disorders". American Family Physician 79 (2): 109–16. PMID 19178061.
- ^ coast of Maine spots - General Practice Notebook
- ^ "Cafe Au Lait Spots", by William D James, MD
- ^ Cafe Au Lait Spots
- ^ Arnsmeier, Sheryl L.; Riccardi, Vincent M.; Paller, Amy S. (1994). "Familial Multiple Cafe au lait Spots". Arch Dermatol. 130 (11): 1425–1426. doi:10.1001/archderm.1994.01690110091015. PMID 7979446.
- ^ Whyte, M. P.; Podgornik, M. N.; Zerega, J.; Reinus, W. R. (2000). "Café-au-lait spots caused by vitiligo in McCune-Albright syndrome". J Bone Miner Res. 15 (12): 2521–2523. doi:10.1359/jbmr.2000.15.12.2521. PMID 11127218.
- ^ Scheinfeld, Noah S.; et al. (2011). "Laser Treatment of Benign Pigmented Lesions". MedScape Reference.
External links
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Wikimedia Commons has media related to Café au lait spot. |
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Look up cafe au lait or macule in Wiktionary, the free dictionary. |
Pigmentation disorders/Dyschromia (L80–L81, 709.0)
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Hypo-/
leucism |
Loss of melanocytes |
vitiligo: |
- Quadrichrome vitiligo
- Vitiligo ponctué
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syndromic |
- Alezzandrini syndrome
- Vogt–Koyanagi–Harada syndrome
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melanocyte development: |
- Piebaldism
- Waardenburg syndrome
- Tietz syndrome
|
|
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Loss of melanin/
amelanism |
albinism: |
- Oculocutaneous albinism
- Ocular albinism
|
|
melanosome transfer: |
- Hermansky–Pudlak syndrome
- Chédiak–Higashi syndrome
- Griscelli syndrome
- Elejalde syndrome
- Griscelli syndrome type 2
- Griscelli syndrome type 3
|
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other: |
- Cross syndrome
- ABCD syndrome
- Albinism–deafness syndrome
- Idiopathic guttate hypomelanosis
- Phylloid hypomelanosis
- Progressive macular hypomelanosis
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Leukoderma w/o
hypomelanosis |
- Vasospastic macule
- Woronoff's ring
- Nevus anemicus
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Ungrouped |
- Nevus depigmentosus
- Postinflammatory hypopigmentation
- Pityriasis alba
- Vagabond's leukomelanoderma
- Yemenite deaf-blind hypopigmentation syndrome
- Wende–Bauckus syndrome
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|
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Hyper- |
Melanin/
Melanosis/
Melanism |
Reticulated |
- Dermatopathia pigmentosa reticularis
- Pigmentatio reticularis faciei et colli
- Reticulate acropigmentation of Kitamura
- Reticular pigmented anomaly of the flexures
- Naegeli–Franceschetti–Jadassohn syndrome
- Dyskeratosis congenita
- X-linked reticulate pigmentary disorder
- Galli–Galli disease
- Revesz syndrome
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Diffuse/
circumscribed |
- Lentigo/Lentiginosis: Lentigo simplex
- Liver spot
- Centrofacial lentiginosis
- Generalized lentiginosis
- Inherited patterned lentiginosis in black persons
- Ink spot lentigo
- Lentigo maligna
- Mucosal lentigines
- Partial unilateral lentiginosis
- PUVA lentigines
- Melasma
- Erythema dyschromicum perstans
- Lichen planus pigmentosus
- Café au lait spot
- Poikiloderma (Poikiloderma of Civatte
- Poikiloderma vasculare atrophicans)
- Riehl melanosis
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Linear |
- Incontinentia pigmenti
- Scratch dermatitis
- Shiitake mushroom dermatitis
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Other/ungrouped |
- Acanthosis nigricans
- Freckle
- Familial progressive hyperpigmentation
- Pallister–Killian syndrome
- Periorbital hyperpigmentation
- Photoleukomelanodermatitis of Kobori
- Postinflammatory hyperpigmentation
- Transient neonatal pustular melanosis
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Other
pigments |
iron: |
- Hemochromatosis
- Iron metallic discoloration
- Pigmented purpuric dermatosis
- Schamberg disease
- Majocchi's disease
- Gougerot–Blum syndrome
- Doucas and Kapetanakis pigmented purpura/Eczematid-like purpura of Doucas and Kapetanakis
- Lichen aureus
- Angioma serpiginosum
- Hemosiderin hyperpigmentation
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other metals: |
- Argyria
- Chrysiasis
- Arsenic poisoning
- Lead poisoning
- Titanium metallic discoloration
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other: |
- Carotenosis
- Tattoo
- Tar melanosis
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Dyschromatoses |
- Dyschromatosis symmetrica hereditaria
- Dyschromatosis universalis hereditaria
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noco (i/b/d/q/u/r/p/m/k/v/f)/cong/tumr (n/e/d), sysi/epon
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proc, drug (D2/3/4/5/8/11)
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UpToDate Contents
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English Journal
- Optic pathway glioma as part of a constitutional mismatch-repair deficiency syndrome in a patient meeting the criteria for neurofibromatosis type 1.
- Yeung JT, Pollack IF, Shah S, Jaffe R, Nikiforova M, Jakacki RI.SourceDoris Duke Clinical Research Fellowship, Department of Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
- Pediatric blood & cancer.Pediatr Blood Cancer.2013 Jan;60(1):137-9. doi: 10.1002/pbc.24254. Epub 2012 Jul 27.
- Patients with constitutional mismatch repair-deficiency (CMMR-D) caused by the biallelic deletions of mismatch repair (MMR) genes have a high likelihood of developing malignancies of the bone marrow, bowel, and brain. Affected individuals often have phenotypic features of neurofibromatosis type 1 (N
- PMID 22848017
- Anuric Acute Kidney Injury in Neurofibromatosis 1.
- Khan U, Razdan R, Perazella MA.SourceDepartment of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, CT; Program of Applied Translational Research, Department of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, CT. Electronic address: usman.khan@yale.edu.
- American journal of kidney diseases : the official journal of the National Kidney Foundation.Am J Kidney Dis.2012 Nov 20. pii: S0272-6386(12)01322-4. doi: 10.1053/j.ajkd.2012.08.044. [Epub ahead of print]
- Neurofibromatosis is one of several genetic disorders characterized by hyperpigmented skin spots (café au lait spots) and multiple neurofibromas. It was first reported by Friedrich Daniel von Recklinghausen in 1882. There are 2 types of neurofibromatosis described in the literature: von Recklinghau
- PMID 23177704
Japanese Journal
- 皮膚にカフェオレ斑を有し, 小児期に線維性骨異形成症と診断され, 先端肥大症の疑いで紹介された19歳の男性
- 18トリソミーの患者に生じカフェオレ斑を伴ったXantholeukemiaの1例
- 緊急手術を要した巨大な胸部solitary fibrous tumor合併von Recklinghausen病患者の一例
- 四方 裕夫,橋本 泰司,石井 修,渡 正伸,渡橋 和政,渡邊 洋宇,松原 純一,末田 泰二郎,松浦 雄一郎
- 日本呼吸器外科学会雑誌 14(7), 854-859, 2000-11-15
- … 大径10×8×6cm大の比較的軟らかな球状結節を十数個認めた.CD34, Desmin, Vimentin, NSE, S-100, AE1/AE3, α-smooth muscle actinなどの免疫組織化学的染色でSolitary Fibrous Tumorと診断された.皮膚のcafe-au-lait spot部と皮下結節の病理組織的検索を行い術前に疑われたvon Recklinghausen病と合致した.術後経過は良好で術後24病日に転院となった.転院後1ヵ月で退院したが, 1年後脳梗塞発生時に …
- NAID 110001271324
Related Links
- photo by Janelle Aby, MD Cafe au lait spots are lighter in color than melanocytic nevi, but they also may be congenital macules. They are caused by an increased amount of melanin in both melanocytes and epidermal cells, and may ...
- Neurofibromatosis type 1: the cognitive phenotype. J Pediatr. Apr 1994;124(4):S1-8. [Medline]. Johnson BL, Charneco DR. Café au lait spot in neurofibromatosis and in normal individuals. Arch Dermatol. Oct 1970;102(4):442-6. [Medline]. Listernick R, Darling C, Greenwald M, Strauss L, Charrow J.
Related Pictures
★リンクテーブル★
[★]
[★]
- 英
- cafe-au-lait spot cafe-au-lait spots cafe-au-lait spot cafe-au-lait spots, cafe au lait spot
- 同
- ミルクコーヒー斑、cafe au lait斑
- 関
- 神経線維腫症
[★]
- 関
- dot、local、locoregional、mottle、point、regional、stigma、stigmata
[★]
金
- 関
- gold、golden