カフェオレ斑
WordNet
- mark with a spot or spots so as to allow easy recognition; "spot the areas that one should clearly identify"
- a small piece or quantity of something; "a spot of tea"; "a bit of paper"; "a bit of lint"; "I gave him a bit of my mind" (同)bit
- a small contrasting part of something; "a bald spot"; "a leopards spots"; "a patch of clouds"; "patches of thin ice"; "a fleck of red" (同)speckle, dapple, patch, fleck, maculation
- a business establishment for entertainment; "night spot"
- a playing card with a specified number of pips on it to indicate its value; "an eight-spot"
- a mark on a die or on a playing card (shape depending on the suit) (同)pip
- a section of an entertainment that is assigned to a specific performer or performance; "they changed his spot on the program"
- a short section or illustration (as between radio or tv programs or in a magazine) that is often used for advertising
- make a spot or mark onto; "The wine spotted the tablecloth" (同)fleck, blob, blot
- detect with the senses; "The fleeing convicts were picked out of the darkness by the watchful prison guards"; "I cant make out the faces in this photograph" (同)recognize, recognise, distinguish, discern, pick out, make_out, tell apart
- become spotted; "This dress spots quickly"
- a small restaurant where drinks and snacks are sold (同)coffeehouse, coffee_shop, coffee_bar
- the syllable naming the sixth (submediant) note of a major or minor scale in solmization (同)lah
PrepTutorEJDIC
- 『斑点』(はんてん),まだら,ぶち;(太陽の)黒点 / 『しみ』,よごれ;吹出物,にきび / (…に対する)汚名,汚点《+『on』+『名』》 / 『場所』,地点;部分,箇所 / (順序・組織における)位置;立場,おかれた状況 / 《a spot》《英話》(…の)少量,ちょっぴり(の…);(…の)1杯《+『of』+『名』》 / (ラジオ・テレビ番組の)構成区分 / …‘を'『しみで汚す』,‘に'汚れをつける;…‘に'斑点(はんてん)をつける,‘を'まだら(ぶち)にする;( …で)…‘に'しみ(斑点)をつける《+『名』+『with』+『名』》 / 〈人格・名声など〉‘を'汚す,傷つける / (特定の場所に)…‘を'置く,配置する / …‘を'見つける;(…だと)…‘を'見抜く《+『名』+『as』(『for』)+『名』》 / 〈インクなどが〉『しみになる』;〈布などが〉汚れる / 即座になされる,即時払いの(引き渡しの) / 現場での,現地の / (ラジオ・テレビで)番組の間に放送される / ちょうど,ぴったり(exactly)
- 〈C〉『喫茶店』(coffeehouse),小レストラン);《英》(酒類を出さない)『軽食堂』 / 〈C〉バー,キャバレー,ナイトクラブ
- ラ(全音階の第6音)
- goldの化学記号
- circa
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/09/13 19:43:10」(JST)
[Wiki en表示]
Café au lait spot |
A café au lait spot on a patient's left cheek.
|
Classification and external resources |
Specialty |
dermatology |
ICD-10 |
L81.3 |
ICD-9-CM |
709.09 |
DiseasesDB |
16118 |
eMedicine |
ped/2754 |
MeSH |
D019080 |
See also: List of conditions associated with café au lait macules
Café au lait spots or café au lait macules are flat, pigmented birthmarks.[1] The name café au lait is French for "coffee with milk" and refers to their light-brown color. They are also called "giraffe spots" or "coast of Maine spots".[2]
They are caused by a collection of pigmented-producing melanocytes in the epidermis of the skin.[3]
These spots are typically permanent, and may grow or increase in number over time.[4]
Cafe au Lait spots are often harmless, but may be associated with syndromes such as Neurofibromatosis Type 1 and McCune-Albright syndrome.[4]
Contents
- 1 Etiology
- 2 Diagnosis
- 3 Prognosis
- 4 Treatment
- 5 See also
- 6 References
- 7 External links
Etiology
Neurofibromatosis type I café au lait spot
Café au lait spots can arise from diverse and unrelated causes:[5][6]
- Having six or more café au lait spots greater than 5 mm in diameter before puberty, or greater than 15 mm in diameter after puberty, is a diagnostic feature of neurofibromatosis type I, but other features are required to diagnose NF-1.[3]
- Familial multiple café au lait spots have been observed without NF-1 diagnosis.[7]
- They can be caused by vitiligo in the rare McCune–Albright syndrome.[8]
- Legius syndrome
- Tuberous sclerosis
- Fanconi anemia, a rare genetic disease.
- Idiopathic
- Ataxia telangiectasia
- Basal cell nevus syndrome
- Benign congenital skin lesion
- Bloom syndrome
- Chediak Higashi syndrome
- Congenital naevus
- Gaucher disease
- Hunter syndrome
- Maffucci syndrome
- Multiple mucosal neuroma syndrome
- Noonan syndrome
- Pulmonary Stenosis
- Silver–Russell syndrome
- Watson syndrome
- Wiskott–Aldrich syndrome
Diagnosis
Diagnosis is visual with measurement of spot size and count of number of spots having clinical significance for diagnosis of associated disorders such as Neurofibromatosis type I. Usually, more than 6 spots more than 3 cm in diameter indicates NF1.
Prognosis
Café au Lait spots are usually present at birth, permanent, and may grow in size or increase in number over time.[4]
Cafe au Lait spots are themselves benign and do not cause any illness or problems. However, they may be associated with syndromes such as Neurofibromatosis Type 1 and McCune-Albright syndrome.[4]
The size and shape of the spots do not have any meaning or implications with regards to diagnosis of associated syndromes.[3]
Treatment
Cafe au lait spots can be removed with lasers.[9] Unfortunately results are variable as the spots are often not completely removed or can come back after treatment. Often, a test spot is treated first to help predict the likelihood of treatment success.[10]
See also
- Birthmark
- Nevus
- List of cutaneous conditions
- List of conditions associated with café au lait macules
References
- ^ Plensdorf S, Martinez J (January 2009). "Common pigmentation disorders". American Family Physician 79 (2): 109–16. PMID 19178061.
- ^ coast of Maine spots - General Practice Notebook
- ^ a b c al.], editors, Lowell A. Goldsmith ... [et (2012). Fitzpatrick's dermatology in general medicine (8th ed.). New York: McGraw-Hill Medical. pp. Chapter 141. ISBN 978-0-07-166904-7.
- ^ a b c d Morelli, JG (2013). CURRENT Diagnosis & Treatment: Pediatrics, 22e. New York, NY: McGraw-Hill. pp. Chapter 15: Skin. ISBN 978-0-07-182734-8.
- ^ "Cafe Au Lait Spots", by William D James, MD
- ^ Cafe Au Lait Spots
- ^ Arnsmeier, Sheryl L.; Riccardi, Vincent M.; Paller, Amy S. (1994). "Familial Multiple Cafe au lait Spots". Arch Dermatol. 130 (11): 1425–1426. doi:10.1001/archderm.1994.01690110091015. PMID 7979446.
- ^ Whyte, M. P.; Podgornik, M. N.; Zerega, J.; Reinus, W. R. (2000). "Café-au-lait spots caused by vitiligo in McCune-Albright syndrome". J Bone Miner Res. 15 (12): 2521–2523. doi:10.1359/jbmr.2000.15.12.2521. PMID 11127218.
- ^ Scheinfeld, Noah S. et al. (2011). "Laser Treatment of Benign Pigmented Lesions". MedScape Reference.
- ^ al.], editors, Lowell A. Goldsmith ... [et (2012). Fitzpatrick's dermatology in general medicine (8th ed.). New York: McGraw-Hill Medical. pp. Chapter 239. ISBN 978-0-07-166904-7.
External links
|
Wikimedia Commons has media related to Café au lait spot. |
|
Look up cafe au lait or macule in Wiktionary, the free dictionary. |
UpToDate Contents
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English Journal
- The natural history of spinal neurofibromatosis: a critical review of clinical and genetic features.
- Ruggieri M1, Polizzi A, Spalice A, Salpietro V, Caltabiano R, D'Orazi V, Pavone P, Pirrone C, Magro G, Platania N, Cavallaro S, Muglia M, Nicita F.
- Clinical genetics.Clin Genet.2015 May;87(5):401-10. doi: 10.1111/cge.12498. Epub 2014 Nov 22.
- Spinal neurofibromatosis (SNF) is a related form of neurofibromatosis 1 (NF1), characterized by bilateral neurofibromas (histologically proven) of all spinal roots (and, eventually, of all the major peripheral nerve branches) with or without other manifestations of classical NF1. By rigorous applica
- PMID 25211147
- Unusual histological variant of malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation.
- Shete S1, Bolde S1, Pandit G1, Matkari P1, Ingle SB1.
- World journal of clinical cases.World J Clin Cases.2015 Apr 16;3(4):389-92. doi: 10.12998/wjcc.v3.i4.389.
- Malignant peripheral nerve sheath tumor (MPNST) with rhabdomyoblastic differentiation is called as malignant triton tumor (MTT). It is highly aggressive soft tissue tumor with higher local recurrence rate. MTT has poor prognosis than MPNST. MTT seems to be more aggressive in patients with neurofibro
- PMID 25879014
- Lumbar Lipomeningomyelocele Associated with Multiple Café au Lait Spots: A Case Report.
- Balasubramanian P1, Srinivas CR1, Arunachalam P2, Thirumurthy KS3, Rajkumar PR3, Manuvidhya H1.
- Pediatric dermatology.Pediatr Dermatol.2015 May;32(3):e78-e81. doi: 10.1111/pde.12557. Epub 2015 Mar 19.
- We report on a child with several café au lait spots in association with a lumbar lipomeningomyelocele as an apparently new association. Cutaneous markers, the identification of which plays a crucial role in the early diagnosis and management of spinal malformations, can accompany occult spinal dys
- PMID 25786983
Japanese Journal
- Jaffe-Campanacci syndrome に osteosarcoma を発症した1例
- 佐竹 崇志,大野 貴敏,大島 康司,永野 昭仁,清水 克時
- 中部日本整形外科災害外科学会雑誌. 中部日本整形外科災害外科学会抄録 56(2), 383-384, 2013-03-01
- NAID 10031174896
- Unknown Case : Low Back Pain in a Patient With Cafe au Lait Spots
- Unknown Case : Low Back Pain in a Patient With Cafe Au Lait Spots
Related Links
- Café au lait spots, or café au lait (CAL) macules (CALMs), are hyperpigmented lesions that may vary in color from light brown to dark brown; this is reflected by the name of the condition, which means
- Most café-au-lait spots are smooth, oval birthmarks. They range in color from light brown to chocolate brown and usually are found on the torso, buttocks, and legs. ... Cafe-au-lait spots are light tan or light brown spots that are ...
Related Pictures
★リンクテーブル★
[★]
- 英
- cafe-au-lait spot cafe-au-lait spots cafe-au-lait spot cafe-au-lait spots, cafe au lait spot
- 同
- ミルクコーヒー斑、cafe au lait斑
- 関
- 神経線維腫症
[★]
- 関
- dot、local、locoregional、mottle、point、regional、stigma、stigmata
[★]
金
- 関
- gold、golden