WordNet
- of critical importance and consequence; "an acute (or critical) lack of research funds"
- having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
- extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
- having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
- of an angle; less than 90 degrees
- nephritis marked by inflammation of the glomeruli of the kidney; characterized by decreased production of urine and by the presence of blood and protein in the urine and by edema
PrepTutorEJDIC
- (先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
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- 1. 溶連菌感染後糸球体腎炎 poststreptococcal glomerulonephritis
- 2. 糸球体疾患の鑑別診断および評価 differential diagnosis and evaluation of glomerular disease
- 3. 成人におけるブドウ球菌随伴糸球体腎炎 staphylococcus associated glomerulonephritis in adults
- 4. 小児における糸球体腎炎の病因と原因の概要 overview of the pathogenesis and causes of glomerulonephritis in children
- 5. A群レンサ球菌：病原性因子および発症機序 group a streptococcus virulence factors and pathogenic mechanisms
English Journal
- Disease manifestations and pathogenic mechanisms of group a Streptococcus.
- Walker MJ1, Barnett TC, McArthur JD, Cole JN, Gillen CM, Henningham A, Sriprakash KS, Sanderson-Smith ML, Nizet V.
- Clinical microbiology reviews.Clin Microbiol Rev.2014 Apr;27(2):264-301. doi: 10.1128/CMR.00101-13.
- Streptococcus pyogenes, also known as group A Streptococcus (GAS), causes mild human infections such as pharyngitis and impetigo and serious infections such as necrotizing fasciitis and streptococcal toxic shock syndrome. Furthermore, repeated GAS infections may trigger autoimmune diseases, includin
- PMID 24696436
- Posterior reversible encephalopathy syndrome in children: report of three cases.
- Akın F1, Kılıçaslan C, Solak ES, Uzun M, Aygün S, Arslan Ş.
- Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery.Childs Nerv Syst.2014 Mar;30(3):535-40. doi: 10.1007/s00381-013-2342-y. Epub 2013 Dec 20.
- PURPOSE: Posterior reversible encephalopathy syndrome (PRES) is a condition characterized by varying degrees of headache, nausea, vomiting, visual disturbances, focal neurologic deficit, and seizures due to severe systemic hypertension. The knowledge of secondary hypertension in children is most com
- PMID 24356805
- How to use antistreptolysin O titre.
- Sen ES1, Ramanan AV.
- Archives of disease in childhood. Education and practice edition.Arch Dis Child Educ Pract Ed.2014 Jan 30. doi: 10.1136/archdischild-2013-304884. [Epub ahead of print]
- Group A streptococcus (GAS) is the cause of a wide range of acute suppurative and, following a latent period, non-suppurative diseases such as rheumatic fever and poststreptococcal glomerulonephritis. Diagnosis of the latter group requires evidence of preceding GAS infection. The bacteria produce a
- PMID 24482289
Japanese Journal
- 臨床研究・症例報告 細菌性肺炎に急性腎障害を伴い,後日溶連菌感染後急性糸球体腎炎合併と診断した1例
- 水川 花織,小林 貴子,山田 伸治 [他]
- 小児科臨床 66(11), 2251-2255, 2013-11
- NAID 40019828568
- 症例 膜性腎症に著明な半月体形成を合併した溶連菌感染後糸球体腎炎の1例
- 松田 潤,長山 郁恵,山口 嘉土 [他]
- The Japanese journal of nephrology = 日本腎臓学会誌 55(4), 567-573, 2013
- NAID 40019754148
- PFAPAを背景にもつ重症溶連菌感染後急性糸球体腎炎の1例
- 渡邊 祥二郎,千葉 奈歩,相澤 知美,敦賀 和志,伊藤 悦朗,城 謙輔,尾田 高志,田中 完
- Nihon Shoni Jinzobyo Gakkai Zasshi 26(1), 110-115, 2013
- … 溶連菌感染後急性糸球体腎炎(poststreptococcal acute glomerulonephritis; …
- NAID 130003384547
Related Links
- Acute Poststreptococcal Glomerulonephritis. Acute glomerulonephritis is a disease characterized by the sudden appearance of edema, hematuria, proteinuria, and hypertension. ... The course and prognosis for acute ...
- [2, 3] In a study of leukocytes and glomeruli obtained from 22 pediatric patients with acute poststreptococcal glomerulonephritis (APSGN), Wu et al found evidence that in cases of nephritis, the 15-lipoxygenase derivatives lipoxin A 4 (LXA 4 ) and 15-S-hyroxyeicosatetraenoic acid (15-S-HETE) have anti ...
Related Pictures
★リンクテーブル★
| リンク元 | 「溶連菌感染後急性糸球体腎炎」「急性溶連菌感染後性糸球体腎炎」 |
| 関連記事 | 「acute」「poststreptococcal glomerulonephritis」「poststreptococcal」「glomerulonephritis」 |
「溶連菌感染後急性糸球体腎炎」
- 英
- poststreptococcal acute glomerulonephritis PSAGN
- 同
- 急性溶連菌性糸球体腎炎 acute poststreptococcal glomerulonephritis
- 連鎖球菌感染後糸球体腎炎 poststreptococcal glomerulonephritis poststrepococcal GN, post-streptococcal glomerulonephritis
- 猩紅熱腎炎 scarlatinal nephritis
- 関
- 非溶連菌性感染後急性糸球体腎炎、急性糸球体腎炎、糸球体腎炎。IgA腎症
- first aid step1 2006 p.385(Glomerular pathology)
概念
- A群β溶血性連鎖球菌感染症後に1-2週間して発症するnephritic syndrome
疫学
- 学童期(5-8歳)に後発
病因
- A群β溶血性連鎖球菌感染後(上気道炎、皮膚膿痂疹)に続発
- 潜伏期：1-2週間 ← IgA腎症との鑑別点
病態
- 溶連菌成分を抗原とする抗体が産生されて免疫複合体が形成され、この免疫複合体が糸球体基底膜に沈着し(上皮側)、III型アレルギーの機序により補体活性化、多形白血球浸潤、ケミカルメディエーターの放出が起こる。
病理
- 光顕：管内性増殖性糸球体腎炎
- 糸球体の腫大、富核、白血球の浸潤 ← 白血球の浸潤と糸球体内の細胞の増殖による
- 蛍光抗体法：係蹄壁へのC3の顆粒状沈着
- 電顕：上皮細胞下沈着物(ハンプ) → subepithelial humps on EM
症状
- 血尿、浮腫、高血圧、蛋白尿、乏尿
検査
- 抗ストレプトリジンO抗体(ASO)上昇
- 補体価低下：C3低下, CH50低下
- 腎機能低下：クレアチニン上昇、カリウム上昇、尿素窒素上昇
- 腎生検：
- 糸球体係蹄壁への顆粒状C3の沈着、IgGの沈着は50-60%の例に認められる。
合併症
- うっ血性心不全、高血圧性脳症、急性腎不全
治療
- 対症療法
- 急性期：安静、食事療法(水分制限、塩分制限、蛋白制限)
- 薬物療法：必要に応じて
- 利尿薬：フロセミド
- 降圧薬：カルシウム拮抗薬
予後
- 良好。90%以上が1-3ヶ月で治癒。一部急性期に死亡/慢性腎不全への移行(SPE.596)
USMLE
- Q book p.244 30
参考
- 1. [charged] poststreptococcal-glomerulonephritis - uptodate [1]
国試
「急性溶連菌感染後性糸球体腎炎」
「acute」
- adj.
- (疾患)急性の、急性型の、急性的な。(形状が)鋭い、鋭角の。(感覚、才知などが)鋭い。明敏な、鋭い眼識のある。
「poststreptococcal glomerulonephritis」
「poststreptococcal」
- adj.
- 連鎖球菌感染後の
「glomerulonephritis」