- 関
- XIAP
- 抗アポトーシス因子
WordNet
- the means of connection between things linked in series (同)nexus
- a unit of length equal to 1/100 of a chain
- an interconnecting circuit between two or more locations for the purpose of transmitting and receiving data (同)data link
- a fastener that serves to join or connect; "the walls are held together with metal links placed in the wet mortar during construction" (同)linkup, tie, tie-in
- (computing) an instruction that connects one part of a program or an element on a list to another program or list
- limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
- control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
- limit the range or extent of; "Contact between the young was inhibited by strict social customs"
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a substance that retards or stops an activity
PrepTutorEJDIC
- (鎖の)『輪』,環 / 鎖のようにつながったソーセージの一節 / (…と)つなぐ物(人),(…との)きずな,つながり《+『with』(『to』)+『名』》 / 《複数形で》=cuff links / …‘を'『つなぎ合わせる』,連結する;(…と)…‘を'つなぐ《+『名』+『with』(『to』)+『名』》 / (…と)結合する,つながる《+[『up』(『together』)]『with』+『名』》
- たいまつ
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
- 〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
- 蛋白(たんばく)質
- 抑制する人(物) / 化学反応抑制剤
UpToDate Contents
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- 1. 原発性免疫不全症の診断のためのフローサイトメトリー flow cytometry for the diagnosis of primary immunodeficiencies
- 2. アポトーシスと自己免疫疾患 apoptosis and autoimmune disease
- 3. ペリツェウス・メルツバッハー病 pelizaeus merzbacher disease
- 4. Reperfusion injury of the heart
- 5. 慢性骨髄性白血病の細胞生物学および分子生物学 cellular and molecular biology of chronic myeloid leukemia
English Journal
- Ginsenoside compound K sensitizes human colon cancer cells to TRAIL-induced apoptosis via autophagy-dependent and -independent DR5 upregulation.
- Chen L1, Meng Y1, Sun Q1, Zhang Z1, Guo X1, Sheng X1, Tai G1, Cheng H1, Zhou Y1.
- Cell death & disease.Cell Death Dis.2016 Aug 11;7(8):e2334. doi: 10.1038/cddis.2016.234.
- Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a potent cancer cell-specific apoptosis-inducing cytokine with little toxicity to most normal cells. However, acquired resistance of cancer cells to TRAIL is a roadblock. Agents that can either potentiate the effect of TRAIL or
- PMID 27512955
- USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma.
- Engel K1, Rudelius M2, Slawska J1, Jacobs L1, Ahangarian Abhari B3, Altmann B4, Kurutz J1, Rathakrishnan A1, Fernández-Sáiz V5, Brunner A1, Targosz BS1, Loewecke F1, Gloeckner CJ6, Ueffing M7, Fulda S8, Pfreundschuh M9, Trümper L10, Klapper W11, Keller U5, Jost PJ1, Rosenwald A2, Peschel C5, Bassermann F12.
- EMBO molecular medicine.EMBO Mol Med.2016 Aug 1;8(8):851-62. doi: 10.15252/emmm.201506047.
- The mitotic spindle assembly checkpoint (SAC) maintains genome stability and marks an important target for antineoplastic therapies. However, it has remained unclear how cells execute cell fate decisions under conditions of SAC-induced mitotic arrest. Here, we identify USP9X as the mitotic deubiquit
- PMID 27317434
- XIAP inhibits mature Smac-induced apoptosis by degrading it through ubiquitination in NSCLC.
- Qin S1, Yang C2, Zhang B1, Li X1, Sun X1, Li G1, Zhang J1, Xiao G1, Gao X1, Huang G1, Wang P1, Ren H1.
- International journal of oncology.Int J Oncol.2016 Jul 27. doi: 10.3892/ijo.2016.3634. [Epub ahead of print]
- X-linked inhibitor of apoptosis protein (XIAP) and second mitochondrial-derived activator of caspase (Smac) are two important prognostic biomarkers for cancer. They are negatively correlated in many types of cancer. However, their relationship is still unknown in lung cancer. In the present study, w
- PMID 27498621
Japanese Journal
- X連鎖リンパ増殖症候群--SAP欠損症とXIAP欠損症 (AYUMI 血球貪食症候群の発症機構に迫る)
- 金兼 弘和
- 医学のあゆみ 238(11), 1058-1064, 2011-09-10
- NAID 40018973514
- Heme Oxygenase-1 Inhibition Prevents Intimal Hyperplasia Enhancing Nitric Oxide-Dependent Apoptosis of Vascular Smooth Muscle Cells
- Cerrito Maria Grazia,Scagliarini Alessandra,Froio Alberto,Liloia Angela,Busnelli Marco,Giovannoni Roberto,Otterbein Leo Edmond,Mainetti Lara,Villa Matteo,Bach Fritz Heintz,Leone Biagio Eugenio,Biasi Giorgio Maria,Lavitrano Marialuisa
- Biological & Pharmaceutical Bulletin 34(8), 1204-1214, 2011
- … however the role of these genes remains unclear. … We show, in a model of balloon injury in rats, that the suppression of vascular smooth muscle cells (VSMC) proliferation by NO required HO-1, while induction of apoptosis of the VSMC by NO does not involve HO-1. …
- NAID 130000936588
Related Links
- Successful amelioration of cardiac dysfunction and heart failure through gene therapy approaches will require a transgene effective at attenuating myocardial injury, and subsequent remodeling, using an efficient and safe delivery ...
- X-linked Inhibitor of apoptosis protein (XIAP) has been classically identified as a cell death regulator. Here, we demonstrate a novel function of XIAP as a regulator of neurite outgrowth in neuronal cells. In PC12 cells, XIAP ...
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★リンクテーブル★
| リンク元 | 「XIAP」「X連鎖アポトーシス抑制タンパク質」 |
| 関連記事 | 「link」「inhibit」「inhibitor」「linked」「X」 |
「XIAP」
- X連鎖ア・トーシス抑制タンパク質
「X連鎖アポトーシス抑制タンパク質」
「link」
- n.
- v.
- 関連づける、連結する、連接する
- 関
- associate、association、attach、bearing、bind、catenate、catenation、concatenation、connect、connection、correlate、correlation、implicate、implication、join、juncture、ligate、ligation、linkage、linked、pertinent、reference、relate、relation、relationship、relative、relevance、relevant
「inhibit」
- v.
- 抑制する、阻害する、阻止する
- 関
- abrogate、block、depress、depression、deter、inhibition、interdict、prevent、prevention、repress、repression、restrain、restraint、suppress、suppression
「inhibitor」
- n.
「linked」
- adj.
- 連鎖の、連鎖的な、連鎖性の