Ly-1B細胞。CD5B細胞
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
- the 2nd letter of the Roman alphabet (同)b
- the blood group whose red cells carry the B antigen (同)type_B, group B
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- carbonの化学記号
- certificate of deposit / (また『C.D.』)Civil Defense民間防衛
UpToDate Contents
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English Journal
- Utility of Quantitative Flow Cytometry Immunophenotypic Analysis of CD5 Expression in Small B-Cell Neoplasms.
- Challagundla P1, Jorgensen JL, Kanagal-Shamanna R, Gurevich I, Pierson DM, Ferrajoli A, Reyes SR, Medeiros LJ, Miranda RN.
- Archives of pathology & laboratory medicine.Arch Pathol Lab Med.2014 Jul;138(7):903-9. doi: 10.5858/arpa.2013-0367-OA.
- Context.-The value of assessing CD5 expression in the differential diagnosis of small B-cell neoplasms is well established. Assessment is usually done qualitatively. Objectives.-To assess CD5 expression levels by quantitative flow cytometry immunophenotyping and to determine possible differences amo
- PMID 24978916
- Follicular Lymphoma With Progression to Diffuse Large B-Cell Lymphoma and Concurrent CD5-Negative Mantle Cell Lymphoma-3 Entities in a Lymph Node.
- Trimaldi JA, Bowers JW, Bello C, Sagatys EM.
- Cancer control : journal of the Moffitt Cancer Center.Cancer Control.2014 Jul;21(3):251-4.
- PMID 24955711
- Interaction of CD5 and CD72 is involved in regulatory T and B cell homeostasis.
- Zheng M1, Xing C, Xiao H, Ma N, Wang X, Han G, Chen G, Hou C, Shen B, Li Y, Wang R.
- Immunological investigations.Immunol Invest.2014 Jun 20:1-12. [Epub ahead of print]
- Regulatory IL-10-producing CD1dhighCD5+CD19+ B cells and CD4+CD25+Foxp3+ T cells have been found to modulate immune responses in autoimmunity, infection, and cancer, but the interaction between these two cell subsets remains unclear. Through cell culture and flow cytometry (FACS), we analyzed the in
- PMID 24950378
Japanese Journal
- CD5陽性腫瘍細胞の小血管内浸潤を認めたびまん性大細胞型B細胞リンパ腫
- Down-regulation of CD5 expression on activated CD8+ T cells in familial hemophagocytic lymphohistiocytosis with perforin gene mutations
- Wada Taizo,Sakakibara Yasuhisa,Nishimura Ryosei,Toma Tomoko,Ueno Yasuhisa,Horita Seiki,Tanaka Taihei,Nishi Masanori,Kato Keisuke,Yasumi Takahiro,Ohara Osamu,Yachie Akihiro
- Human Immunology 74(12), 1579-1585, 2013-12
- … We have recently described a significant increase in the subpopulation of CD8+ T cells with clonal expansion and CD5 down-regulation in Epstein-Barr virus associated-HLH, which represented a valuable tool for its diagnosis. … All patients showed significantly increased subpopulations of activated CD8+ T cells with down-regulation of CD5, which were negligible among normal controls. … Analysis of T-cell receptor Vβ repertoire suggested the reactive and oligoclonal expansion of these cells. …
- NAID 120005349176
- CD5陽性びまん性大細胞型B細胞リンパ腫 : 疾患単位に関する現状認識と今後の課題 (特集 びまん性大細胞型B細胞リンパ腫の診断と治療 : Update in 2013)
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- CD5抗原は,分子量67kDaの単鎖膜糖タンパクで,成熟T細胞,胸腺細胞,一部のB細胞に存在します。CD5陽性B細胞(B-1細胞)は通常のB細胞とは異なり,脾臓等,異所由来(骨髄非依存性)のB細胞として区別しています。また,B細胞性白血病 ...
★リンクテーブル★
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- 英
- Ly-1 B cell
- 同
- CD5B細胞 CD5 B cell、B1細胞 B1 cell
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- 同
- B-1 B cell, CD5 B cell, CD5 B cells
- 同
- CD5 B cells
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- 同
- Leucine-1
発現細胞
- 胸腺細胞、T細胞、B細胞のサブセット (IMM)
- 胸腺細胞、T細胞、NK細胞、B1(B細胞のsubpopulation) (WCH.31)
- 成熟T細胞、胸腺細胞、一部のB細胞(CD5陽性B細胞(B-1細胞)。脾臓等、異所由来(骨髄非依存性)のB細胞) (資料1)
- B細胞性白血病・リンパ腫(資料1)
分子量
別名
機能
- CD5に対するモノクローナル抗体を作用させると、細胞内のチロシンのリン酸化が起こり、T細胞が活性化する。ただし、抑制的に作用する経路にも作用するかもしれない(WCH.31)
- CD5+ B細胞は自己抗体を産生する(WCH.31)
- CD72はCD5にたいするcounter-receptorである(WCH.31)
臨床関連
参考
- http://www.srl.info/srlinfo/kensa_ref_CD/KENSA/SRL5039.htm
- http://www.bc-cytometry.com/Data/db_search/CD005.htm
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- Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する
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細胞