- 英
- C3b inactivator deficiency
- 関
- I因子欠損症
WordNet
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
PrepTutorEJDIC
- carbonの化学記号
UpToDate Contents
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- 1. 補体経路complement pathways [show details]
… As the convertase cleaves more C3 to C3b, an amplification loop is set in motion, resulting in the deposition of large amounts of C3b on the target. C3b,… substitute for an antibody and an antigen, and MASP replaces the C1 complex proteases. An inherited deficiency of MASP-2 has been described . The alternative pathway is an ancient pathway of innate immunity …
- 2. 補体系の概要および臨床的評価overview and clinical assessment of the complement system [show details]
… million C3b fragments may be deposited on a single bacterium. Once a target is coated with C3b, it can then be recognized by host cells bearing complement receptors. The process of C3b on a target… homozygous deficiency of a classical pathway component. C1q, C4, C2, or C3 deficiency could present this way. If the infecting organism is a Neisserial species, then C5, C6, C7, C8, or C9 deficiency should…
- 3. リウマチ性血管炎の病因と発症機序etiology and pathogenesis of rheumatoid vasculitis [show details]
…part, to decreased expression of complement receptors and a decreased ability to degrade activated C3b . More significantly, patients with RV have a high incidence of antibodies against C1q . These antibodies…
- 4. 自然免疫系の概要an overview of the innate immune system [show details]
…complement cascade upon binding to antibody that is fixed to a microbe. The resulting attachment of C3b promotes phagocytosis of (ie, opsonizes) the microbe. Antimicrobial peptides (AMPs) are a group … traumatic injury of epithelium elicits inflammatory cytokines that induce beta-defensin production . Deficiency of HBD1 in sperm is associated with male infertility . Cathelicidins are a family of AMPs widely …
- 5. 補体系の制御因子および受容体regulators and receptors of the complement system [show details]
… Factor H regulates C3b, C3b-containing alternative pathway convertases, and C5 convertases that contain either one C3b (from the complement pathway/lectin pathway) or two C3bs (alternative… A deficiency of CD59 is a common finding in adult patients with paroxysmal nocturnal hemoglobinuria (PNH). The deficiency is caused by a mutation…
★リンクテーブル★
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- 英
- factor I deficiency
- 同
- C3b不活性化因子欠損症 C3b inactivator deficiency
- 関
- I因子、C3b不活性化因子
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C3b不活性化因子欠損症
[★]
- 英
-
- 同
- 欠損症
- 関
- 異常、遺伝子欠失、欠く、欠失、欠損症、欠点、欠乏、欠乏症、欠乏性、欠落、削除、除去、ディリーション、発育不全、非形成、不完全、不十分、不足、無形成、欠くこと、欠陥、失う、ミス
概念
- 本来存在するはずのものが、まったく失われている状態。
[★]
- 関
- 補体
- 古典的経路:C3からC4b2aのもつC3 convatase活性により生成し、C4b2a3bはC5 convertase活性を持つ (2008前期免疫学プリント 68)
- 別経路:C3からC3bBbPのもつC3 convertase活性により生成し、n(C3bBb)はC5 convertase活性を持つ (2008前期免疫学プリント 68)
- 別経路では細菌の表面でC3bが安定的に存在→オプソニン作用を有する
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- 同
- 補体第三成分 third component of complement
- 関
- 補体、C3a, C3b
- 補体の一つ
- C3は血清中に最も多く存在する
- C3 convertaseによってC3aとC3bを生じる
- C3 convertase活性を持つのは2つ
- 1. C4bC2a (古典的経路)
- 2. C3bBbP (別経路)
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[★]
- 英
- defect、deficiency、absence、morphological defect
- 関
- 異常、欠失、欠神、欠損、欠点、欠乏、欠乏症、欠乏性、非存在、ないこと、欠くこと、欠如、欠陥、形態異常