- 日
- アスペルギルス・テレウス
- 関
- アスペルギルス属
WordNet
- genus of common molds causing food spoilage and some pathogenic to plants and animals (同)genus Aspergillus
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/08/20 17:20:39」(JST)
[Wiki en表示]
Aspergillus parasiticus |
Scientific classification |
Kingdom: |
Fungi |
Division: |
Ascomycota |
Class: |
Eurotiomycetes |
Order: |
Eurotiales |
Family: |
Trichocomaceae |
Genus: |
Aspergillus |
Species: |
A. terreus |
Binomial name |
Aspergillus terreus
Thom (1918)[1] |
Aspergillus terreus is a fungus (mold) commonly used in industry to produce important organic acids, such as itaconic acid and cis-aconitic acid. It was also the initial source for the drug mevinolin (lovastatin), a drug for lowering serum cholesterol. A. terreus may cause opportunistic infection in people with deficient immune systems. It is refractory to amphotericin B therapy.[2]
A. terreus also produces aspterric acid and 6-hydroxymellein, inhibitors of pollen development in Arabidopsis thaliana.[3]
References[edit source | edit]
- ^ Thom C, Church MB. (1918). "Aspergillus fumigatus, A. nidulans, A. terreus n. sp. and their allies". American Journal of Botany 5 (2): 84–104. doi:10.2307/2435130.
- ^ http://www.doctorfungus.org/thefungi/Aspergillus_terreus.php
- ^ Shimada, A.; Kusano, M.; Takeuchi, S.; Fujioka, S.; Inokuchi, T.; Kimura, Y. (2002). "Aspterric acid and 6-hydroxymellein, inhibitors of pollen development in Arabidopsis thaliana, produced by Aspergillus terreus". Zeitschrift fur Naturforschung. C, Journal of biosciences 57 (5–6): 459–464. PMID 12132685.
UpToDate Contents
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English Journal
- Production of cellulases by solid state fermentation with Aspergillus terreus and enzymatic hydrolysis of mild alkali-treated rice straw.
- Narra M, Dixit G, Divecha J, Madamwar D, Shah AR.SourceSardar Patel Renewable Energy Research Institute, P.O. Box 2, Vallabh Vidyanagar 388 120, Gujarat, India.
- Bioresource technology.Bioresour Technol.2012 Oct;121:355-61. Epub 2012 Jul 16.
- Rice straw was used as substrate for cellulase production by solid state fermentation with Aspergillus terreus. Substrate concentration, moisture ratio, inoculum size and initial pH were optimized using response surface methodology involving Box-Behnken design. The predicted filter paper activity un
- PMID 22864171
- Animal Bone Char Solubilization with Itaconic Acid Produced by Free and Immobilized Aspergillus terreus Grown on Glycerol-Based Medium.
- Vassilev N, Medina A, Eichler-Löbermann B, Flor-Peregrín E, Vassileva M.SourceDepartment of Chemical Engineering, Faculty of Sciences, University of Granada, c/Fuentenueva s/n, Granada, 18071, Spain, nbvass@yahoo.com.
- Applied biochemistry and biotechnology.Appl Biochem Biotechnol.2012 Sep 6. [Epub ahead of print]
- Cells of Aspergillus terreus, free and immobilized in polyurethane foam, were employed in itaconic acid fermentation processes on glycerol-based media. The purpose was to assess their suitability for animal bone char solubilization and the development of a biotechnological alternative to P fertilize
- PMID 22956279
Japanese Journal
- Synthetic studies toward antitumor sesquiterpenoid quadrone
- Ishihata Akihiro,Saeki Megumi,Watanabe Masaru [他]
- Heterocycles 80(2), 903-907, 2010-03-01
- NAID 40016991465
- Butyrolactones from the Fungus Aspergillus terreus BCC 4651
- Haritakun Rachada,Rachtawee Pranee,Chanthaket Rungtiwa,Boonyuen Nattawut,Isaka Masahiko
- CHEMICAL & PHARMACEUTICAL BULLETIN 58(11), 1545-1548, 2010
- … Two new butenolides, butyrolactones VI (1) and VII (2), were isolated together with six known compounds, butyrolactones I (3), II (4), IV (5), and V (6), aspernolide B (7), and bisdethiodi(methylthio)acetylaranotin (8) from the fungus Aspergillus terreus BCC 4651. …
- NAID 130000405675
- Butenolide and Furandione from an Endophytic Aspergillus terreus
- Nuclear Paulwatt,Sommit Damrong,Boonyuen Nattawut,Pudhom Khanitha
- CHEMICAL & PHARMACEUTICAL BULLETIN 58(9), 1221-1223, 2010
- … A new butenolide, aspernolide D (1), and furandione, asperterone (2), together with four known butenolides, butyrolactones I—IV and aspernolide B, were obtained from cultures of the endophytic fungus Aspergillus terreus, isolated from the flowering plant Mammea siamensis. …
- NAID 130000324598
Related Links
- Aspergillus terreus, also known as Aspergillus terrestrius, is a fungus (mold) found worldwide in soil. Although thought to be strictly asexual until recently, A. terreus is now known to be capable of sexual reproduction. [2] This saprotrophic ...
- Aspergillus species A. terreus (Thom). View more images Colony characteristics. Colonies (CzA) yellowish-brown to cinnamon-brown, consisting of a dense felt of conidiophores. Microscopy. Conidiophore stipes smooth walled ...
Related Pictures
★リンクテーブル★
[★]
- ラ
- Aspergillus
- 同
- Aspergillus属
- 同
- コウジカビ
- 関
- アスペルギルス症
- ラクトフェノール・コトン青による染色で
生物的特徴
- 真菌
- 腐生性の不完全菌に属する糸状菌
- 有隔性菌糸を持つ(branching septate hyphae)
- 土壌や朽ちた植物に存在。空気中に浮遊胞子として存在。アスペルギルスの分生子は暖かく湿った場所で多く作られる → 空調器のエアフィルターや加湿器などで増殖
- 日和見病原体。基礎疾患(好中球減少や免疫不全症)を有する患者に感染
感染経路
- A. fumigatusの胞子は2-3.5umで、気管支に達し肺を冒す
アスペルギルス属
感染症
- 肺アスペルギローマ:結核・気管支拡張症などで生じた空洞・嚢胞で分生子が生長・増殖し、大きな菌糸塊を形成 菌球形成
- 侵襲性アスペルギルス症:好中球機能不全などの患者に発生し、より急性でより重症やしやすい。肺・消化管障害、心内膜炎、脳・骨膿瘍、全身播種
- アレルギー性気管支肺アスペルギルス症:喘息様発作、末梢血好中球増加、中枢性気管支拡張
[★]
- 英
- micafungin, MCFG
- 化
- ミカファンギンナトリウム micafungin sodium
- 商
- ファンガード
- 関
- 抗真菌薬
作用機序
薬理作用
用量
スペクトラム
無効
相互作用
副作用
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アスペルギルス属