アルツハイマー病
WordNet
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- mental deterioration of organic or functional origin (同)dementedness
- writing done with a typewriter (同)typewriting
PrepTutorEJDIC
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- (医学的な)痴呆(ちほう)
UpToDate Contents
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English Journal
- Prodromal posterior cortical atrophy: clinical, neuropsychological, and radiological correlation.
- Chan LT1, Lynch W, De May M, Horton JC, Miller BL, Rabinovici GD.
- Neurocase.Neurocase.2015 Feb;21(1):44-55. doi: 10.1080/13554794.2013.860176. Epub 2013 Dec 5.
- We present longitudinal clinical, cognitive, and neuroimaging data from a 63-year-old woman who enrolled in research as a normal control and evolved posterior cortical atrophy (PCA) over 5 year follow-up. At baseline she reported only subtle difficulty driving and performed normally on cognitive te
- PMID 24308559
- Learning sung lyrics aids retention in normal ageing and Alzheimer's disease.
- Moussard A1, Bigand E, Belleville S, Peretz I.
- Neuropsychological rehabilitation.Neuropsychol Rehabil.2014 Dec;24(6):894-917. doi: 10.1080/09602011.2014.917982. Epub 2014 Jun 2.
- Previous studies have suggested that presenting to-be-memorised lyrics in a singing mode, instead of a speaking mode, may facilitate learning and retention in normal adults. In this study, seven healthy older adults and eight participants with mild Alzheimer's disease (AD) learned and memorised lyri
- PMID 24881953
- Developing a new apathy measurement scale: Dimensional Apathy Scale.
- Radakovic R1, Abrahams S2.
- Psychiatry research.Psychiatry Res.2014 Nov 30;219(3):658-63. doi: 10.1016/j.psychres.2014.06.010. Epub 2014 Jun 19.
- Apathy is both a symptom and syndrome prevalent in neurodegenerative disease, including motor system disorders, that affects motivation to display goal directed functions. Levy and Dubois (2006) suggested three apathetic subtypes, Cognitive, Emotional-affective and Auto-activation, all with discrete
- PMID 24972546
Japanese Journal
- アルツハイマー型認知症の臨床的改善に対するリバスチグミンの効果 (特集 新しいアルツハイマー型認知症治療薬の使用経験) -- (リバスチグミンの使用経験)
- 血管性認知症,アルツハイマー型認知症の認知機能と発達に基づいたADL能力の関連
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Related Pictures
★リンクテーブル★
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- 英
- Alzheimer disease, Alzheimer's disease
- 同
- (国試)Alzheimer病、(以下、厳密には同義ではない)→アルツハイマー型認知症、アルツハイマー型痴呆 dementia of the Alzheimer type DAT, Alzheimer-type dementia Alzheimer type dementia ATD
- Alzheimer型痴呆、Alzheimer型認知症
- 関
- ドネペジル、認知症
概念
進行性痴呆のなかで脳血管障害による痴呆に次いで多い (EPT.257)
- 大脳皮質のびまん性萎縮が見られる (EPT.257)
- 前脳基底野コリン作動性ニューロンの選択的な変性が見られ、アセチルコリンの産生が低下
- 病理学的には、老人斑とアルツハイマー神経線維変化が見られる (EPT.257)
疫学
- 有病率:65歳以上5-10%。65~69歳:1.5%、85歳~:27.3%。
- 認知症の半数がアルツハイマー病
- アルツハイマー病の5-10%が家族性
アルツハイマーのリスクファクター
- 高コレステロール
- 血圧
- ホモシステイン
- 糖尿病。内臓脂肪(メタボリックシンドローム)
- 喫煙
病理
- 老人斑:細胞外にβアミロイドが沈着。
- 神経原線維変化:細胞内にリン酸化されたタウ蛋白が凝集し、らせん構造をとる
症状
1. 中核症状
- 1. 健忘(記銘力、記憶力)
- 2. 見当識障害
- 3. 思考力障害
- 4. 計算力障害
2. 周辺症状
- 不安、抑うつ、徘徊、不眠、妄想、せん妄、幻覚、暴行、焦燥感
他疾患との比較
未分類
- 空間視の障害:例えば立方体の模写ができない。頭頂葉の障害とされる。
- 着衣失行
検査
./t_image/103/103D003.jpg
国試
[★]
- (windows)ファイル内容表示(linux -> cat])
- ex. type report_20111118.jp.htm | php a.php > report_20111118.jp.jp.jp.html
- 関
- form、mode、pattern、type specimen、typed
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- 関
- dementia、dementing、deterioration
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- 関
- form、mode、pattern、type
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