… metabolic changes leading to abnormal biliary lipid secretion . Cirrhosis is a risk factor for pigment gallstones. Only a small proportion of patients with cirrhosis have cholesterol stones. The increased …
…spherocytes on the blood smear , or the individual may be symptomatic from anemia, splenomegaly, pigment gallstones, or jaundice. Jaundice due to severe hemolysis is less common after the newborn period. In …
…bilirubin excretion can lead to brown or black pigment stones consisting of precipitated monoconjugated and unconjugated bile pigments. Black pigment stones generally form in the gallbladder and may contain …
…hepatitis, iron overload, and (combined with the effects of chronic hemolysis) the development of pigment gallstones, all of which may contribute to the development of liver disease. The term "sickle cell …