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1. 思春期早発症の定義、原因、および評価definition etiology and evaluation of precocious puberty [show details]
… approach to treatment for peripheral precocity depends on the cause. GnRH agonist therapy is ineffective, in contrast to patients with central precocious puberty (CPP). In the following discussion, the causes …
2. 緊急時のオピオイド離脱opioid withdrawal in the emergency setting [show details]
… patients with normal or elevated blood pressure, an alpha-2 adrenergic agonist may be administered. Clonidine binds to a central alpha-2 adrenergic receptor that shares potassium channels with opioids …
3. クロニジンおよびイミダゾリンによる中毒clonidine and related imidazoline poisoning [show details]
…of indications. Guanfacine, and the antispasticity agent tizanidine, are also oral central alpha-2 adrenergic agonist medications that are being more commonly prescribed. Related imidazolines are found …
4. 小児や青年の不眠症への薬物療法：エビデンスに基づいた治療法pharmacotherapy for insomnia in children and adolescents a rational approach [show details]
…of using this class of drugs for sleep are summarized in the table Clonidine is a central alpha-2-adrenergic agonist that decreases adrenergic tone. It is one of the most widely used medications for insomnia …
5. 薬物熱drug fever [show details]
…is a distinct entity . Serotonin syndrome is a predictable consequence of excess agonist activity of serotonin on central and peripheral 5-HT1A and 5-HT2A receptors . Features include agitation, confusion …