WordNet
- in or near a center or constituting a center; the inner area; "a central position"
- a workplace that serves as a telecommunications facility where lines from telephones can be connected together to permit communication (同)telephone exchange, exchange
- use recreational drugs (同)do drugs
- administer a drug to; "They drugged the kidnapped tourist" (同)dose
- a substance that is used as a medicine or narcotic
- the performance of a part or role in a drama (同)playing, playacting, performing
- serving temporarily especially as a substitute; "the acting president"
- in or near or toward a center or according to a central role or function; "The theater is centrally located"
- one of the proteins into which actomyosin can be split; can exist in either a globular or a fibrous form
PrepTutorEJDIC
- 『中心の』,中央の,中心からの / 『主要な』,中心的な(main) / (音声が)中舌音の / 電話交換局(《英》[telephone]exchange)
- 『薬』,薬品,薬剤 / 『麻薬』,麻酔剤 / 〈人〉‘に'薬(特に麻酔剤)を与える / 〈飲食物〉‘に'(麻酔薬・毒薬などの)薬を混ぜる
- 代理の,臨時の / 演出用の / 演出,演技
- 中心に,中央に
- 純蛋白質(筋肉生成に役立つ)
UpToDate Contents
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English Journal
- Neuromodulatory role of angiotensin-(1-7) in the central nervous system.
- Gironacci MM, Longo Carbajosa NA, Goldstein J, Cerrato BD.SourceDepartamento de Química Biológica, Instituto de Química y Fisicoquímica Biológicas-CONICET, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina. mariela@qb.ffyb.uba.ar
- Clinical science (London, England : 1979).Clin Sci (Lond).2013 Jul 1;125(2):57-65. doi: 10.1042/CS20120652.
- Ang-(1-7) [angiotensin-(1-7)] constitutes an important functional end-product of the RAS (renin-angiotensin system) endogenously formed from AngI (angiotensin I) or AngII (angiotensin II) through the catalytic activity of ACE2 (angiotensin-converting enzyme 2), prolyl carboxypeptidase, neutral endop
- PMID 23530669
- Blocking central galanin receptors attenuates insulin sensitivity in myocytes of diabetic trained rats.
- Bu L, Liu Z, Zou J, Gao X, Bao Y, Qu S.SourceDepartment of Endocrinology, Shanghai 10th People's Hospital, Tongji University School of Medicine, Shanghai, China.
- Journal of neuroscience research.J Neurosci Res.2013 Jul;91(7):971-7. doi: 10.1002/jnr.23228. Epub 2013 May 7.
- Galanin (Gal), a bioactive neuropeptide, is widely distributed throughout the central nervous system and has diverse modulatory effects. To understand the central effect of this training-stimulatory peptide on insulin sensitivity, its antagonist M35 was injected into the cerebral ventricle in type 2
- PMID 23653288
- Mechanisms of resistance to anti-angiogenesis therapies.
- Giuliano S, Pagès G.SourceUniversity of Nice Sophia Antipolis, Institute for Research on Cancer and Aging of Nice (IRCAN) CNRS Unit 7284/INSERM Unit 1081, 33 Avenue de Valombrose, 06189 Nice, France.
- Biochimie.Biochimie.2013 Jun;95(6):1110-9. doi: 10.1016/j.biochi.2013.03.002. Epub 2013 Mar 16.
- Angiogenesis, the formation of new blood vessels from preexisting ones, provides oxygen and nutrients to actively proliferating tumor cells. Hence, it represents a critical aspect of tumor progression and metastasis. Because inhibition of angiogenesis represents a major approach to cancer treatment,
- PMID 23507428
Japanese Journal
- Tipepidine enhances the antinociceptive-like action of carbamazepine in the acetic acid writhing test
- Kazuaki Kawaura,Risa Miki,Yuri Urashima,Sokichi Honda,Ahmed M. Shehata,Fumio Soeda,Tetsuya Shirasaki,Kazuo Takahama,カワウラ カズアキ,ミキ リサ,ウラシマ ユリ,ホンダ ソウキチ,ソエダ フミオ,シラサキ テツヤ,タカハマ カズオ,川浦 一晃,三木 理沙,浦嶋 優里,本田 宗吉,副田 二三夫,白崎 哲哉,高濱 和夫
- European Journal of Pharmacology 651(1-3), 106-108, 2011-01-25
- … Recently, wereported that the centrally acting non-narcotic antitussive (cough suppressant drug),tipepidine produces an antidepressant-like effect in the forced swimming test, althoughthe mechanism of action appears to be quite different from that of knownantidepressants. …
- NAID 120003020802
- GIRKチャネルは新規排尿障害治療薬の標的になり得るか?
- 山本 巌,副田 二三夫,白 哲哉 [他],高濱 和夫
- YAKUGAKU ZASSHI 131(4), 523-532, 2011
- … On the other hand, little or no therapeutic drug is available for dysuria after CI. … We previously reported that dextromethorphan (DM) and cloperastine (CP), centrally acting antitussives, reduce the frequency of micturition reflex and increase the threshold pressure in anesthetized rats. …
- NAID 130000678832
- Antidepressant-like effect of centrally acting non-narcotic antitussive caramiphen in a forced swimming test
- Kazuaki Kawaura,Risa Miki,Eriko Shima,Sokichi Honda,Fumio Soeda,Tetsuya Shirasaki,Kazuo Takahama,カワウラ カズアキ,ミキ リサ,シマ エリコ,ホンダ ソウキチ,ソエダ フミオ,シラサキ テツヤ,タカハマ カズオ,川浦 一晃,三木 理沙,島 絵里子,本田 宗吉,副田 二三夫,白崎 哲哉,高濱 和夫
- Neuroscience Letters 481(3), 188-190, 2010-09
- … Recently, we reported that a centrally acting non-narcotic antitussive (cough suppressant drug),tipepidine produces an antidepressant-like effect in the forced swimming test in rats. … Becausepharmacological properties of tipepidine apparently differ from those of typical antidepressantsdeveloped to date, we speculated that caramiphen, another centrally acting antitussive, has anantidepressant-like effect. …
- NAID 120003020800
Related Links
- Central-acting agents, also called central adrenergic inhibitors, treat several conditions, including high blood pressure, drug and alcohol withdrawal, and hot flashes. Find out more about these medications. By Mayo Clinic staff. Central- acting ...
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