置換システイン到達性評価
- 関
- SCAM
WordNet
- be a substitute; "The young teacher had to substitute for the sick colleague"; "The skim milk substitutes for cream--we are on a strict diet" (同)sub, stand in, fill_in
- a person or thing that takes or can take the place of another (同)replacement
- an athlete who plays only when a starter on the team is replaced (同)reserve, second-stringer
- act as a substitute; "She stood in for the soprano who suffered from a cold" (同)deputize, deputise, step in
- put in the place of another; switch seemingly equivalent items; "the con artist replaced the original with a fake Rembrandt"; "substitute regular milk with fat-free milk"; "synonyms can be interchanged without a changing the contexts meaning" (同)replace, interchange, exchange
- a way of doing something, especially a systematic way; implies an orderly logical arrangement (usually in steps)
- an amino acid containing sulfur that is found in most proteins; oxidizes on exposure to air to form cystine
PrepTutorEJDIC
- (…の)『代りをする人(物)』,補欠(選手など),代用品《+for+名》 / …‘を'(…の)『代りに用いる』《+名+for+名》 / (…の)『代りをする』《+for+名》
- 〈C〉(特に秩序だった)(…の)『方法』,方式《+『of』+『名』(do『ing』)》 / 〈C〉〈U〉(思考行・行為・行動の)きちょうめんさ;秩序,筋道
- 近づきやすいこと,手に入りやすいこと / 影響されやすいこと
UpToDate Contents
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English Journal
- Topography of the TH5 Segment in the Diphtheria Toxin T-Domain Channel.
- Kienker PK1, Wu Z2,3, Finkelstein A2,4.
- The Journal of membrane biology.J Membr Biol.2015 Dec 8. [Epub ahead of print]
- The translocation domain (T-domain) of diphtheria toxin contains 10 α helices in the aqueous crystal structure. Upon exposure to a planar lipid bilayer under acidic conditions, it inserts to form a channel and transport the attached amino-terminal catalytic domain across the membrane. The TH5, TH8,
- PMID 26645703
- The active site of yeast phosphatidylinositol synthase Pis1 is facing the cytosol.
- Bochud A1, Conzelmann A2.
- Biochimica et biophysica acta.Biochim Biophys Acta.2015 May;1851(5):629-40. doi: 10.1016/j.bbalip.2015.02.006. Epub 2015 Feb 14.
- Five yeast enzymes synthesizing various glycerophospholipids belong to the CDP-alcohol phosphatidyltransferase (CAPT) superfamily. They only share the so-called CAPT motif, which forms the active site of all these enzymes. Bioinformatic tools predict the CAPT motif of phosphatidylinositol synthase P
- PMID 25687304
- A dualistic conformational response to substrate binding in the human serotonin transporter reveals a high affinity state for serotonin.
- Bjerregaard H1, Severinsen K1, Said S1, Wiborg O1, Sinning S2.
- The Journal of biological chemistry.J Biol Chem.2015 Mar 20;290(12):7747-55. doi: 10.1074/jbc.M114.573477. Epub 2015 Jan 22.
- Serotonergic neurotransmission is modulated by the membrane-embedded serotonin transporter (SERT). SERT mediates the reuptake of serotonin into the presynaptic neurons. Conformational changes in SERT occur upon binding of ions and substrate and are crucial for translocation of serotonin across the m
- PMID 25614630
Japanese Journal
- Identification of the Carboxyl-Terminal Membrane-Anchoring Region of HPC-1/Syntaxin 1A with the Substituted-Cysteine-Accessibility Method and Monoclonal Antibodies
- Identification of the Carboxyl-Terminal Membrane-Anchoring Region of HPC-1/Syntaxin 1A with the Substituted-Cysteine-Accessibility Method and Monoclonal Antibodies
Related Links
- 1. Methods. 2005 Jun;36(2):148-71. Transmembrane protein topology mapping by the substituted cysteine accessibility method (SCAM(TM)): application to lipid-specific membrane protein topogenesis. Bogdanov M(1), Zhang W, Xie ...
- 1. Curr Protoc Neurosci. 2001 May;Chapter 4:Unit 4.15. doi: 10.1002/0471142301.ns0415s08. The substituted-cysteine accessibility method (SCAM) to elucidate membrane protein structure. Liapakis G(1), Simpson MM, Javitch JA. ...
★リンクテーブル★
[★]
- 英
- substituted cysteine accessibility method、SCAM
- 外部露出しているアミノ酸残基をシステイン置換と修飾試薬を用いて決定する方法
[★]
置換システイン到達性評価
- 関
- substituted cysteine accessibility method
[★]
- 関
- alternatively、displace、displacement、in place of、instead、proxy、replace、replacement、substitution、substitutional、surrogate
[★]
- 関
- assay、fashion、law、manner、means、method for measurement、-metry、mode、procedure、process、system、technique、way
[★]
- 関
- convenience、handiness