有棘細胞癌、棘細胞癌
WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- any malignant tumor derived from epithelial tissue; one of the four major types of cancer
- having spines; "the dorsal fin is spinous" (同)spiny
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- がん,がん腫
UpToDate Contents
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English Journal
- Aberrant epidermal differentiation and disrupted ΔNp63/Notch regulatory axis in Ets1 transgenic mice.
- Chin SS1, Romano RA, Nagarajan P, Sinha S, Garrett-Sinha LA.
- Biology open.Biol Open.2013 Dec 15;2(12):1336-45. doi: 10.1242/bio.20135397.
- The transcription factor Ets1 is expressed at low levels in epidermal keratinocytes under physiological conditions, but is over-expressed in cutaneous squamous cell carcinoma (SCC). We previously showed that over-expression of Ets1 in differentiated keratinocytes of the skin leads to significant pro
- PMID 24337118
- USP9X expression correlates with tumor progression and poor prognosis in esophageal squamous cell carcinoma.
- Peng J, Hu Q, Liu W, He X, Cui L, Chen X, Yang M, Liu H, Wei W, Liu S1, Wang H.
- Diagnostic pathology.Diagn Pathol.2013 Oct 23;8:177. doi: 10.1186/1746-1596-8-177.
- BACKGROUND: Ubiquitination is a reversible process of posttranslational protein modification through the action of the family of deubiquitylating enzymes which contain ubiquitin-specific protease 9x (USP9X). Recent evidence indicates that USP9X is involved in the progression of various human cancers
- PMID 24152793
- Altered expression of dermokine in skin disorders.
- Hasegawa M1, Higashi K, Yokoyama C, Yamamoto F, Tachibana T, Matsushita T, Hamaguchi Y, Saito K, Fujimoto M, Takehara K.
- Journal of the European Academy of Dermatology and Venereology : JEADV.J Eur Acad Dermatol Venereol.2013 Jul;27(7):867-75. doi: 10.1111/j.1468-3083.2012.04598.x. Epub 2012 May 31.
- BACKGROUND: Although dermokine-β, a glycoprotein expressed in epithelial cells, does not have significant homology to other proteins, its carboxyl-terminal domain shares a high pI value with many cytokines, suggesting similar functions.OBJECTIVE: To better understand the biology of dermokine, we he
- PMID 22646803
Japanese Journal
- Changes in Elk-1 in the mouse tongue during 4-nitroquinoline 1-oxide-induced carcinogenesis
- Ohnishi Yuichi,Yamasaki Yukinobu,Taguchi Chihiro,Akane Mitsunori,Furukawa Masayuki,Nakajima Masahiro,Kakudo Kenji
- Journal of Osaka Dental University 39(2), 129-132, 2005-10
- … We used immunohistochemical methods and Northern blotting to examine changes in Elk-1 expression in the tissue during carcinogenic transformation in a 4-nitroquinohne 1-oxide (4-NQO)-induced carcinoma model. … In the normal epithelium, Elk-1 was observed in the basal cell layer. … In dysplastic epithelium, it was observed in the basal and spinous cell layers. …
- NAID 110001876537
- Aberrant Expression Patterns of Histone H3 mRNA, p53, Cyclin D1, and Cyclin B1 in Oral Neoplastic Epithelial Lesions
- Nishikawa Tetsunari,Hara Ryohko,Ito Yuichi,Masuno Kazuya,Tominaga Kazuya,Wato Masahiro,Watanabe Yuya,Mori Masahiko,Tanaka Akio
- Acta histochemica et cytochemica = Official Journal of the Japan Society of Histochemistry and Cytochemistry 38(1), 53-59, 2005
- … In verrucous carcinoma (VC, n=22), squamous papilloma (SP, n=18), and hyperkeratotic lesion (HK, n=12), cellular proliferative potentials were evaluated and compared. … However, in 17 cases (77.2%) of VC, co-expression of histone H3 mRNA and p53 protein was found extensively from basal to spinous layers. … While in 20 cases (90.9%) of VC, cyclin D1 was detected from basal to spinous layers, and positive (2+ and 3+) cases (45.4%) increased. …
- NAID 110003161229
Related Links
- Labial Biopsy-Spinous cell carcinoma Philippe ABIMELEC Subscribe Subscribed Unsubscribe 10 Subscription preferences Loading... Loading... Working... Add to Want to watch this again later? Sign in to Like this video? Sign in ...
- spinous cell carcinoma - also known as or related to squamous cell carcinoma of skin, squamous carcinoma, cutaneous squamous cell carcinoma, scc - squamous cell ... Patient.co.uk is one of the most trusted medical resources ...
★リンクテーブル★
[★]
- 英
- squamous cell carcinoma, SCC, prickle cell carcinoma
- 同
- 棘細胞癌 spinous cell carcinoma spinalioma
- ラ
- carcinoma spinocellulare
- 関
- 皮膚癌、扁平上皮癌、有棘細胞
概念
- 先行病変の上に小丘疹~結節を生じる。
- 表皮基底膜を破壊し、浸潤性に肥厚した表皮の内部に異常ケラノサイトを認める。
- 光線角化症(紫外線刺激によって、特に基底層にケラノサイトが悪性化し表皮内で増殖)が悪化してなる。
- 中年以降の男性に好発し、皮膚悪性腫瘍の50%。
リスクファクター
- 紫外線照射
- イオン化放射線
- 免疫抑制
- 慢性炎症
- ヒ素の接触/暴露
- 遺伝子変異:例えば、腫瘍抑制遺伝子のp53の変異など
- 家族歴
- 遺伝性疾患
前癌病変
- 参考1 NDE.392
病理
- 顔面
[show details]
徴候
- 熱傷瘢痕からの発生
[show details]
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参考
- 1. [charged] Epidemiology and risk factors for cutaneous squamous cell carcinoma (SCC) - uptodate [1]
国試
[★]
有棘細胞
- 関
- prickle cell、spinocellular
[★]
細胞