WordNet

suffer or be susceptible to damage; "These fine china cups damage easily"
inflict damage upon; "The snow damaged the roof"; "She damaged the car when she hit the tree"
the act of damaging something or someone (同)harm, hurt, scathe
loss of military equipment (同)equipment casualty
the occurrence of a change for the worse (同)harm, impairment
designed or tending to discredit, especially without positive or helpful suggestions; "negative criticism" (同)negative
(sometimes followed by `to' (同)detrimental, prejudicial, prejudicious
harmed or injured or spoiled; "I wont buy damaged goods"; "the storm left a wake of badly damaged buildings"
a sum of money paid in compensation for loss or injury (同)amends, indemnity, indemnification, restitution, redress

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1. 心臓の虚血性再潅流障害 ischemic reperfusion injury of the heart
2. 急性心筋梗塞中の心室頻拍および心室細動の病因 pathogenesis of ventricular tachycardia and ventricular fibrillation during acute myocardial infarction
3. ST上昇型心筋梗塞における血栓溶解療法：効果の指標 fibrinolytic thrombolytic agents in acute st elevation myocardial infarction markers of efficacy
4. 急性ST上昇型心筋梗塞におけるプライマリ経皮的冠動脈インターベンション後の適正
でない再灌流 suboptimal reperfusion after primary percutaneous coronary intervention in acute st elevation myocardial infarction
5. 初期肺移植片機能不全 primary lung graft dysfunction

Guevara T1.
Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1336:111-21. doi: 10.1007/978-1-4939-2926-9_10.
CDK inhibitors have been used to induce protection in various experimental models. Kidney ischemia-reperfusion (I/R) is a form of acute kidney injury resulting in a cascade of cellular events prompting rapid cellular damage and suppression of kidney function. I/R injury, an inevitable impairment dur
PMID 26231712

Scavenging reactive oxygen species using tempol in the acute phase of renal ischemia/reperfusion and its effects on kidney oxygenation and nitric oxide levels.

Aksu U1, Ergin B, Bezemer R, Kandil A, Milstein DM, Demirci-Tansel C, Ince C.
Intensive care medicine experimental.Intensive Care Med Exp.2015 Dec;3(1):57. doi: 10.1186/s40635-015-0057-y. Epub 2015 Jul 4.
BACKGROUND: Renal ischemia/reperfusion (I/R) injury is commonly seen in kidney transplantation and affects the allograft survival rates. We aimed to test our hypothesis that scavenging reactive oxygen species (ROS) with tempol would protect renal oxygenation and nitric oxide (NO) levels in the acute
PMID 26215821

A randomized clinical trial of ascorbic acid in open abdominal aortic aneurysm repair.

Duffy MJ1, O'Kane CM, Stevenson M, Young IS, Harkin DW, Mullan BA, McAuley DF.
Intensive care medicine experimental.Intensive Care Med Exp.2015 Dec;3(1):50. doi: 10.1186/s40635-015-0050-5. Epub 2015 Jul 1.
BACKGROUND: Open AAA repair is associated with ischaemia-reperfusion injury where systemic inflammation and endothelial dysfunction can lead to multiple organ injury including acute lung injury. Oxidative stress plays a role that may be inhibited by ascorbic acid.METHODS: A double blind, allocation
PMID 26215814

The Effect of Circadian Melatonin Levels on Inflammation and Neurocognitive Functions Following Coronary Bypass Surgery

, , , , , ,
Annals of Thoracic and Cardiovascular Surgery advpub(0), 2015
… Purpose: In this study, the relationship between the plasma levels of melatonin and intercellular adhesion molecule-1 (ICAM-1), which plays role in several intercellular interactions including inflammatory and immune responses, and early neurocognitive functions associated with ischaemia-reperfusion injury during open heart surgery is examined.Methods: Forty patients who were to undergo elective coronary artery bypass grafting (CABG) were divided into two groups, those who underwent their operations at 8 AM (group I; …
NAID 130005072776

Losartan and Sodium Nitroprusside Effectively Protect against Renal Impairments after Ischemia and Reperfusion in Rats

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Biological and Pharmaceutical Bulletin 38(5), 753-762, 2015
… Ischemia and subsequent reperfusion are known to impair renal function. … We examined several agents that might prevent renal impairment or enhance the recovery of renal function after ischemia/reperfusion injury in rats. … Our post-treatment data suggest that losartan and SNP have the greatest potential for therapeutic use to mitigate post-ischemic renal damage and functional impairment. …
NAID 130005068102

Evaluation of Neuronal Protective Effects of Xanthine Oxidoreductase Inhibitors on Severe Whole-brain Ischemia in Mouse Model and Analysis of Xanthine Oxidoreductase Activity in the Mouse Brain

, , , , ,
Neurologia medico-chirurgica 55(1), 77-85, 2015
… Global cerebral ischemia and reperfusion (I/R) often result in high mortality. … Xanthine oxidoreductase (XOR) inhibitors, such as allopurinol, have been reported to protect tissues from damage caused by reactive oxygen species (ROS) by inhibiting its production through XOR inhibition. … Here, we analyzed the effects of allopurinol and febuxostat in decreasing global severe cerebral I/R damage in mice. …
NAID 130004922260