WordNet

relating to or being the keynote of a major or minor scale; "tonic harmony"
a medicine that strengthens and invigorates (同)restorative
(music) the first note of a diatonic scale (同)keynote
lime- or lemon-flavored carbonated water containing quinine (同)tonic_water, quinine water
used of syllables; "a tonic syllables carries the main stress in a word" (同)accented
employing variations in pitch to distinguish meanings of otherwise similar words; "Chinese is a tonal language" (同)tonal
of or relating to or producing normal tone or tonus in muscles or tissue; "a tonic reflex"; "tonic muscle contraction"
a sudden occurrence (or recurrence) of a disease; "he suffered an epileptic seizure" (同)ictus, raptus
the taking possession of something by legal process
causing physical or psychological pain; "worked with painful slowness"

PrepTutorEJDIC

強壮剤;養毛剤,ヘアトニック / (精神的に)元気付けるもの / =tonic water / 主音(音階の中心となる第1音) / 強壮にする,元気付ける / 音調の / (音楽で)主音の
〈U〉〈C〉つかむ(つかまれる)こと / 〈U〉〈C〉強奪;差し押さえ;逮捕 / 〈C〉(病気・恐怖などが)襲うこと,発作
(肉体的・精神的に)『痛い』,苦痛の / 人を苦しめる,やっかいな
(重量単位の)『トン』 / (容積単位の)トン(物によって異なり,木材では40立方フィート,小麦では20立方フィート) / 《話》大量(の…),多数(の…)《+of+名》

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The role of dorsomedial and ventrolateral columns of the periaqueductal gray matter and in situ 5-HT2A and 5-HT2C serotonergic receptors in post-ictal antinociception.

de Freitas RL, de Oliveira RC, de Oliveira R, Paschoalin-Maurin T, de Aguiar Corrêa FM, Coimbra NC.SourceLaboratory of Neuroanatomy and Neuropsychobiology, Department of Pharmacology, School of Medicine of Ribeirão Preto of the University of São Paulo (USP), Av. dos Bandeirantes, 3900, Ribeirão Preto (SP), 14049-900, Brazil; Institute for Neuroscience and Behavior (INeC), Av. do Café, S/N, Ribeirão Preto (SP), Brazil.
Synapse (New York, N.Y.).Synapse.2014 Jan;68(1):16-30. doi: 10.1002/syn.21697. Epub 2013 Oct 22.
The periaqueductal gray matter (PAG) consists in a brainstem structure rich in 5-hydroxytryptamine (5-HT) inputs related to the modulation of pain. The involvement of each of the serotonergic receptor subtypes found in PAG columns, such as the dorsomedial (dmPAG) and the ventrolateral (vlPAG) column
PMID 23913301

Tsuchiya Y, Hoshino J, Suwabe T, Sumida K, Hiramatsu R, Mise K, Hasegawa E, Yamanouchi M, Hayami N, Sawa N, Arizono K, Hara S, Takaichi K, Fujii T, Ubara Y.SourceNephrology Center, Toranomon Hospital , Tokyo , Japan .
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.Amyloid.2013 Dec;20(4):272-4. doi: 10.3109/13506129.2013.837390. Epub 2013 Oct 16.
Abstract We report a Japanese woman with variegate porphyria accompanied by amyloid A (AA) amyloidosis. Arthropathy involving multiple joints occurred at 35 years old and persisted. C-reactive protein was 4.0 mg/dL, but rheumatoid factor was negative. Radiographs did not reveal any loss or narrowi
PMID 24131077

Lacosamide: a review of its use as adjunctive therapy in the management of partial-onset seizures.

Hoy SM.SourceAdis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore, 0754, Auckland, New Zealand, demail@springer.com.
CNS drugs.CNS Drugs.2013 Dec;27(12):1125-42. doi: 10.1007/s40263-013-0123-5.
Lacosamide (Vimpat(®)) is a functionalized amino acid available orally (as a syrup or tablet) and as an intravenous infusion. It is believed to exert its antiepileptic effect by selectively enhancing the slow inactivation of voltage-gated sodium channels. Lacosamide is approved in several countries
PMID 24203890