organ dysfunction

WordNet

1. wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
2. a fully differentiated structural and functional unit in an animal that is specialized for some particular function
3. a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
4. a periodical that is published by a special interest group; "the organ of the communist party"
5. (medicine) any disturbance in the functioning of an organ or body part or a disturbance in the functioning of a social group; "erectile dysfunction"; "sexual relationship dysfunction" (同)disfunction

PrepTutorEJDIC

1. 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
2. 機能障害,機能不全

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/10/23 12:42:16」(JST)

wiki en

[Wiki en表示]

Organ dysfunction is a condition where an organ does not perform its expected function. Organ failure is organ dysfunction to such a degree that normal homeostasis cannot be maintained without external clinical intervention.

It is not a diagnosis. It can be classified by the cause, but when the cause is not known, it can also be classified by whether the onset is chronic or acute.

Multiple organ failure can be associated with sepsis and is often fatal. Countries such as Spain, have shown a rise in mortality risk, due to a large elderly population there.

However, there are tools physicians use when diagnosing multiple organ failure and when prognosing the outcome. The Sequential Organ Failure Assessment (SOFA) score uses early lab values in a patient's hospitalization (within 24 hours) to predict fatal outcomes for a patient.

References

External Links

• Sequential Organ Failure Assessment (SOFA) Score

UpToDate Contents

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• 1. 成人における敗血症症候群：疫学、定義、臨床症状、診断および予後 sepsis syndromes in adults epidemiology definitions clinical presentation diagnosis and prognosis
• 2. 敗血症の病態生理 pathophysiology of sepsis
• 3. 成人における確定診断を得られていない低血圧やショックの評価および初期アプローチ evaluation of and initial approach to the adult patient with undifferentiated hypotension and shock
• 4. 成人におけるショックの定義、症状、病因、および病態生理 definition classification etiology and pathophysiology of shock in adults
• 5. 小児における全身性炎症反応症候群（SIRS）および敗血症：定義、疫学、臨床症状、および診断 systemic inflammatory response syndrome sirs and sepsis in children definitions epidemiology clinical manifestations and diagnosis

English Journal

• Low cardiac index and stroke volume on admission are associated with poor outcome in critically ill burn patients: a retrospective cohort study.

• Soussi S1, Deniau B1, Ferry A1, Levé C1, Benyamina M1, Maurel V1, Chaussard M1, Le Cam B1, Blet A1,2,3, Mimoun M4, Lambert J5, Chaouat M4, Mebazaa A1,2,3, Legrand M6,7,8; PRONOBURN group.
• Annals of intensive care.Ann Intensive Care.2016 Dec;6(1):87. doi: 10.1186/s13613-016-0192-y. Epub 2016 Sep 13.
• BACKGROUND: Impact of early systemic hemodynamic alterations and fluid resuscitation on outcome in the modern burn care remains controversial. We investigate the association between acute-phase systemic hemodynamics, timing of fluid resuscitation and outcome in critically ill burn patients.METHODS:
• PMID 27620877

• Multiple organ dysfunction syndrome in critically ill children: clinical value of two lists of diagnostic criteria.

• Villeneuve A1, Joyal JS1, Proulx F1, Ducruet T1, Poitras N1, Lacroix J2.
• Annals of intensive care.Ann Intensive Care.2016 Dec;6(1):40. doi: 10.1186/s13613-016-0144-6. Epub 2016 Apr 29.
• BACKGROUND: Two sets of diagnostic criteria of paediatric multiple organ dysfunction syndrome (MODS) were published by Proulx in 1996 and by Goldstein in 2005. We hypothesized that this changes the epidemiology of MODS. Thus, we determined the epidemiology of MODS, according to these two sets of dia
• PMID 27130424

Japanese Journal

• 敗血症性ショックに対するPMX治療の臨床評価方法(<特集>アフェレシス療法における臨床評価方法について)

• 清水 智治,遠藤 善裕,谷 徹
• 日本アフェレシス学会雑誌 33(2), 103-109, 2014-05-31
• … We found the improvements in following parameters, such as hemodynamic function indicators (mean arterial pressure, dose of vasopressor, parameter of cardiac function), pulmonary function indicator (PaO_2/FiO_2 ratio, period of ventilator use), renal function indicator (urinary volume, use of renal replacement therapy) and organ dysfunction indicators (SOFA score, APACHE II score). …
• NAID 110009823172

• 急性腎障害と臓器関連 (特集 急性腎障害 : 診断と治療の進歩) -- (特殊な病態と治療法)

• 實吉 拓,北村 健一郎
• 日本内科学会雑誌 103(5), 1123-1129, 2014-05-10
• NAID 40020099471

Related Links

• Non-neurological organ dysfunction in neurocritical care - ISPUB

Purpose: To determine the incidence of non-neurological organ dysfunction in patients with severe neurological injury. Materials and Methods: Modified daily SOFA (mSOFA) scores were retrospectively calculated for 55 consecutive ...

• Organ dysfunction - definition of Organ dysfunction in the ...

sepsis syndrome A constellation of signs, Sx, and systemic responses caused by a wide range of microorganisms that may eventuate into septic shock; SS is a systemic response to infection Sepsis syndrome, defining ...

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★リンクテーブル★

リンク元	「臓器不全」「organ failure」「臓器障害」
拡張検索	「multiple organ dysfunctional syndrome」「multiple organ dysfunction syndrome」「multiorgan dysfunction syndrome」
関連記事	「dysfunction」「organ」

「臓器不全」

　　[★]

英

organ failure、organ dysfunction

関

臓器障害、臓器不全症

「organ failure」

　　[★]

• 臓器不全、臓器不全症

関

organ dysfunction

「臓器障害」

　　[★]

英

organ dysfunction

関

臓器不全

「multiple organ dysfunctional syndrome」

　　[★] 多臓器機能障害症候群

同

MODS

「multiple organ dysfunction syndrome」

　　[★] 多臓器機能障害症候群 MODS

「multiorgan dysfunction syndrome」

　　[★] 多臓器機能障害症候群

「dysfunction」

　　[★]

• n.

• 機能不全、機能障害、機能異常

• vi

• 機能不全に陥る

関

barrier、damage、difficulty、disorder、disturbance、foe、functional disorder、functional impairment、hindrance、hypofunction、impair、impairment、impediment、incompetence、insufficiency、lesion、malfunction、obstacle、stun

　 　

「organ」

　　[★]

• n.

• 臓器、器官