- 関
- organ dysfunction
WordNet
- lack of success; "he felt that his entire life had been a failure"; "that year there was a crop failure"
- loss of ability to function normally; "kidney failure"
- an act that fails; "his failure to pass the test"
- an unexpected omission; "he resented my failure to return his call"; "the mechanics failure to check the brakes"
- a person with a record of failing; someone who loses consistently (同)loser, nonstarter, unsuccessful person
- an event that does not accomplish its intended purpose; "the surprise party was a complete failure"
- wind instrument whose sound is produced by means of pipes arranged in sets supplied with air from a bellows and controlled from a large complex musical keyboard (同)pipe_organ
- a fully differentiated structural and functional unit in an animal that is specialized for some particular function
- a government agency or instrument devoted to the performance of some specific function; "The Census Bureau is an organ of the Commerce Department"
- a periodical that is published by a special interest group; "the organ of the communist party"
PrepTutorEJDIC
- 〈U〉(…における)『失敗』,不成功《+『in』+『名』(do『ing』)》 / 〈C〉失敗者,落後者;失敗した企て,不できなもの / 〈U〉〈C〉怠慢,不履行 / 〈U〉〈C〉(…の)不足,欠乏《+『of』+『名』》 / 〈U〉〈C〉(…の)破産《+『of』+『名』》 / 〈U〉(…の)『衰弱』,減退《+『in』(『of』+『名』》
- 『オルガン』,パイプオルガン(pipe organ),リードオルガン(reed organ),電子オルガン(electronic organ),手回しオルガン(barrel organ) / (動植物の)『器官』 / (政党・会社などの)機関誌,機関紙 / 《しばしば複数形で》(行動・実施などの)組織,機関
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/07/03 06:09:00」(JST)
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Organ dysfunction is a condition where an organ does not perform its expected function. Organ failure is organ dysfunction to such a degree that normal homeostasis cannot be maintained without external clinical intervention.
It is not a diagnosis. It can be classified by the cause, but when the cause is not known, it can also be classified by whether the onset is chronic or acute.
Multiple organ failure can be associated with sepsis.
References
Organ failure
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General |
- Heart failure
- Respiratory failure
- Liver failure
- Acute liver failure
- Chronic liver failure
- Renal failure
- Acute renal failure
- Chronic renal failure
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Multiple |
- Multiple organ dysfunction syndrome
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UpToDate Contents
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English Journal
- Clinical and translational aspects of hypothermia in major trauma patients: From pathophysiology to prevention, prognosis and potential preservation.
- Søreide K.Author information Department of Surgery, Stavanger University Hospital, Stavanger, Norway; Institute of Health and Medicine, University of Stavanger, Stavanger, Norway; Department of Clinical Medicine, University of Bergen, Bergen, Norway. Electronic address: ksoreide@mac.com.AbstractThe human body strives at maintaining homeostasis within fairly tight regulated mechanisms that control vital regulators such as core body temperature, mechanisms of metabolism and endocrine function. While a wide range of medical conditions can influence thermoregulation the most common source of temperature loss in trauma patients includes: exposure (environmental, as well as cavitary), the administration of i.v. fluids, and anaesthesia/loss of shivering mechanisms, and blood loss per se. Loss of temperature can be classified either according to the aetiology (i.e. accidental/spontaneous versus trauma/haemorrhage-induced temperature loss), or according to an unintended, accidental induction in contrast to a medically intended therapeutic hypothermia. Hypothermia occurs infrequently (prevalence<10% of all injured), but more often (30-50%) in the severely injured. Hypothermia usually come together with and may aggravate acidosis and coagulopathy (the "lethal triad of trauma"), which again may be associated with a high mortality. However, recent studies disagree in the independent predictive role of hypothermia and mortality. Prevention of hypothermia is imperative through all phases of trauma care and must be an interest among all team members. Hypothermia in the trauma setting has attracted focus in the past from a pathophysiological, preventive and prognostic perspective; yet recent focus has shifted towards the potential for using hypothermia for pre-emptive and cellular protective purposes. This paper gives a brief update on some of the clinically relevant aspects of hypothermia in the injured patient.
- Injury.Injury.2014 Apr;45(4):647-654. doi: 10.1016/j.injury.2012.12.027. Epub 2013 Jan 23.
- The human body strives at maintaining homeostasis within fairly tight regulated mechanisms that control vital regulators such as core body temperature, mechanisms of metabolism and endocrine function. While a wide range of medical conditions can influence thermoregulation the most common source of t
- PMID 23352151
- Controversies on the origin of proliferating epithelial cells after kidney injury.
- Kusaba T1, Humphreys BD.Author information 1Renal Division, Brigham and Women's Hospital, Boston, MA, USA.AbstractThe kidney possesses the capacity to repair after an acute insult, even one that causes complete organ failure. This regenerative response is characterized by robust proliferation of epithelial cells, principally those located in the proximal tubule. Because defining the origin of these reparative cells has important consequences for stem cell and regenerative approaches to treating kidney injury, this area has been the subject of intense investigation and debate. While progress has been made in narrowing the possible origin of these cells to an intratubular source, there has been no consensus between the possibility of a pre-existing intratubular stem or progenitor cell versus the possibility that fully differentiated epithelial cells re-enter the cell cycle after injury and generate new proximal tubule cells through self-duplication. This review will summarize the evidence on both sides of this active controversy and provide support for the notion that no pre-existing proximal tubule stem cell population exists, but rather all differentiated proximal tubule epithelia have the capacity to proliferate during repair by a mechanism of dedifferentiation and self-duplication.
- Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2014 Apr;29(4):673-9. doi: 10.1007/s00467-013-2669-3. Epub 2013 Dec 10.
- The kidney possesses the capacity to repair after an acute insult, even one that causes complete organ failure. This regenerative response is characterized by robust proliferation of epithelial cells, principally those located in the proximal tubule. Because defining the origin of these reparative c
- PMID 24322596
- Engineering kidneys from simple cell suspensions: an exercise in self-organization.
- Davies JA1, Chang CH.Author information 1University of Edinburgh, Edinburgh, Scotland, UK, jamie.davies@ed.ac.uk.AbstractIncreasing numbers of people approaching and living with end-stage renal disease and failure of the supply of transplantable kidneys to keep pace has created an urgent need for alternative sources of new organs. One possibility is tissue engineering of new organs from stem cells. Adult kidneys are arguably too large and anatomically complex for direct construction, but engineering immature kidneys, transplanting them, and allowing them to mature within the host may be more feasible. In this review, we describe a technique that begins with a suspension of renogenic stem cells and promotes these cells' self-organization into organ rudiments very similar to foetal kidneys, with a collecting duct tree, nephrons, corticomedullary zonation and extended loops of Henle. The engineered rudiments vascularize when transplanted to appropriate vessel-rich sites in bird eggs or adult animals, and show preliminary evidence for physiological function. We hope that this approach might one day be the basis of a clinically useful technique for renal replacement therapy.
- Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2014 Apr;29(4):519-24. doi: 10.1007/s00467-013-2579-4. Epub 2013 Aug 30.
- Increasing numbers of people approaching and living with end-stage renal disease and failure of the supply of transplantable kidneys to keep pace has created an urgent need for alternative sources of new organs. One possibility is tissue engineering of new organs from stem cells. Adult kidneys are a
- PMID 23989397
Japanese Journal
- Relationship between extravascular lung water and severity categories of acute respiratory distress syndrome by the Berlin definition
- Kushimoto Shigeki,Endo Tomoyuki,Yamanouchi Satoshi,Sakamoto Teruo,Ishikura Hiroyasu,Kitazawa Yasuhide,Taira Yasuhiko,Okuchi Kazuo,Tagami Takashi,Watanabe Akihiro,Yamaguchi Junko,Yoshikawa Kazuhide,Sugita Manabu,Kase Yoichi,Kanemura Takashi,Takahashi Hiroyuki,Kuroki Yuuichi,Izumino Hiroo,Rinka Hiroshi,Seo Ryutarou,Takatori Makoto,Kaneko Tadashi,Nakamura Toshiaki,Irahara Takayuki,Saito Nobuyuki
- Critical Care 17(4), R132, 2013-06-20
- … Using the Berlin definition, patients were classified into three categories: mild, moderate, and severe.Results: Compared to patients with mild ARDS, patients with moderate and severe ARDS had higher acute physiology and chronic health evaluation II and sequential organ failure assessment scores on the day of enrollment. …
- NAID 120005341847
- 受傷後短時間で著明な血小板減少を来したマムシ咬傷の1例
- 上田 晃志郎,瀬山 厚司,尼崎 陽太郎,平田 健,井口 智浩,守田 知明
- 山口医学 62(2), 105-109, 2013-05-01
- … In the clinical course, respiratory failure and acute renal failure appeared. … Her respiratory and renal failure improved after a month treatmens. … Multiple organ failure was caused without an anti-mamushi venom. …
- NAID 120005246413
- 症例 腹式子宮筋腫核出術後に腹腔内出血と血胸をきたし多臓器不全となった1症例
Related Links
- Organ Failure is the house band of Super Happy Fun Land, Houston's venue for underground jazz, experimental music, and outsider art. Expect cute, catchy and quirky rock songs about internal distress.
- Organ Failure. 120 likes. Review from The Nashville Scene - Our Critics Picks - November 2006 If you’ve ever wondered what “Folsom Prison Blues” would... ... Weirdo comedy folk rockers Organ Failure have kindly and considerately ...
Related Pictures
★リンクテーブル★
[★]
- 英
- organ failure、organ dysfunction
- 関
- 臓器障害、臓器不全症
[★]
- 英
- organ failure
- 関
- 臓器不全
[★]
多臓器不全評価スコア
[★]
- 失敗、不首尾
- 失敗して企て、不出来なもの、失敗者。(教育)落第、落第点
- 怠慢、不履行(to do)。支払い不能、破産、倒産
- 無いこと。不十分、不足
- (力などの)減退。(医)機能不全。故障。(機)破壊、破損
- 関
- abortion、fail、failing、imperfecta、incompetence、insufficiency、unsuccessful、unsuccessfully
[★]