inbred CFTR mice

近交系CFTRマウス、純系CFTRマウス

WordNet

1. produced by inbreeding
2. the syllable naming the third (mediant) note of any major scale in solmization

PrepTutorEJDIC

1. 生まれつきの(inborn) / 近親交配による
2. ミ(全音階の第3音)
3. mouseの複数形

UpToDate Contents

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• 1. 嚢胞性線維症：遺伝学と病因 cystic fibrosis genetics and pathogenesis
• 2. 嚢胞性線維症：肺疾患治療の概要 cystic fibrosis overview of the treatment of lung disease
• 3. 嚢胞性線維症：実験的治療 cystic fibrosis investigational therapies
• 4. 嚢胞性線維症：臨床症状および診断 cystic fibrosis clinical manifestations and diagnosis
• 5. 嚢胞性線維症：出生前の遺伝学的スクリーニング cystic fibrosis prenatal genetic screening

English Journal

• TGF-β-induced IL-6 prevents development of acute lung injury in influenza A virus-infected F508del CFTR-heterozygous mice.

• Woods PS1, Tazi MF2, Chesarino NM2, Amer AO2, Davis IC3.
• American journal of physiology. Lung cellular and molecular physiology.Am J Physiol Lung Cell Mol Physiol.2015 Jun 1;308(11):L1136-44. doi: 10.1152/ajplung.00078.2015. Epub 2015 Apr 3.
• As the eighth leading cause of annual mortality in the USA, influenza A viruses are a major public health concern. In 20% of patients, severe influenza progresses to acute lung injury (ALI). However, pathophysiological mechanisms underlying ALI development are poorly defined. We reported that, unlik
• PMID 25840995

• CFTR and sphingolipids mediate hypoxic pulmonary vasoconstriction.

• Tabeling C1, Yu H2, Wang L2, Ranke H2, Goldenberg NM3, Zabini D4, Noe E1, Krauszman A2, Gutbier B1, Yin J2, Schaefer M5, Arenz C6, Hocke AC1, Suttorp N1, Proia RL7, Witzenrath M1, Kuebler WM8.
• Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2015 Mar 31;112(13):E1614-23. doi: 10.1073/pnas.1421190112. Epub 2015 Mar 17.
• Hypoxic pulmonary vasoconstriction (HPV) optimizes pulmonary ventilation-perfusion matching in regional hypoxia, but promotes pulmonary hypertension in global hypoxia. Ventilation-perfusion mismatch is a major cause of hypoxemia in cystic fibrosis. We hypothesized that cystic fibrosis transmembrane
• PMID 25829545

• Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology.

• Olivier AK1, Gibson-Corley KN1, Meyerholz DK2.
• American journal of physiology. Gastrointestinal and liver physiology.Am J Physiol Gastrointest Liver Physiol.2015 Mar 15;308(6):G459-71. doi: 10.1152/ajpgi.00146.2014. Epub 2015 Jan 15.
• Multiple organ systems, including the gastrointestinal tract, pancreas, and hepatobiliary systems, are affected by cystic fibrosis (CF). Many of these changes begin early in life and are difficult to study in young CF patients. Recent development of novel CF animal models has expanded opportunities
• PMID 25591863

Related Links

• Mice, inbred cftr - MEDICAL DIAGNOSIS AND MEDICINAL ...

Mice, inbred cftr. On-line free medical diagnosis assistant. Ranked list of possible diseases from either several symptoms or a full patient history. A similarity measure between symptoms and diseases is provided.

• inbred cftr mice - Research -- an open-access journal

Species, Scientific Experts, Publications, Research Grants, Research Topics, Genomes and Genes about inbred cftr mice ... Summary: A strain of mice widely studied as a model for cystic fibrosis. These mice are generated from ...

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★リンクテーブル★

リンク元	「純系CFTRマウス」「近交系CFTRマウス」
関連記事	「CF」「inbred」「mi」「CFTR」「CFT」

「純系CFTRマウス」

　　[★]

英

inbred CFTR mice

関

近交系CFTRマウス

「近交系CFTRマウス」

　　[★]

英

inbred CFTR mice

関

純系CFTRマウス

「CF」

　　[★]

• 冠状動脈血流 冠動脈血流 coronary flow
• 補体結合反応試験 complement fixation test
• 嚢胞性線維症 cystic fibrosis
• ロイコボリン leucovorin calcium
• 登上線維 climbing fiber climbing fibre
• 楔状束 cuneate fasciculus
• 冠血流 coronary flow
• 大腸ファイバースコープ colon fiberscope、大腸内視鏡、下部消化管内視鏡

「inbred」

　　[★]

• 近交系の、純系の、同系繁殖の、同系交配の

関

clone、inbred line、inbred strain、inbreed、inbreeding、pure line

　 　

「mi」

　　[★]

mi-, mio-

• conb form

• より小さい、より少ない。劣った

• ex.

• miosis 縮瞳

？

MI

　 　

「CFTR」

　　[★] 嚢胞性線維症膜貫通調節蛋白質 cystic fibrosis transmembrane regulator

「CFT」

　　[★] セファトリジン cefatrizine