- 関
- clone、inbred、inbred line、pure line
WordNet
- make multiple identical copies of; "people can clone a sheep nowadays"
- a group of genetically identical cells or organisms derived from a single cell or individual by some kind of asexual reproduction (同)clon
- become stretched or tense or taut; "the bodybuilders neck muscles tensed;" "the rope strained when the weight was attached" (同)tense
- (psychology) nervousness resulting from mental stress; "his responsibilities were a constant strain"; "the mental strain of staying alert hour after hour was too much for him" (同)mental strain, nervous strain
- (physics) deformation of a physical body under the action of applied forces
- injury to a muscle (often caused by overuse); results in swelling and pain
- an intense or violent exertion (同)straining
- use to the utmost; exert vigorously or to full capacity; "He really extended himself when he climbed Kilimanjaro"; "Dont strain your mind too much" (同)extend
- produced by inbreeding
- showing signs of mental and emotional tension; "her voice was strained as she asked the question"
PrepTutorEJDIC
- クロン(一個体から無性生殖で増殖した有機体群);(植物の)栄養系,(動物の)分技系
- …‘を'『引っ張る』 / (使い過ぎて)〈体など〉‘を'『痛める』,弱める / …‘を'『最大限に働かせる』,精一杯使う / 〈意味・規則など〉‘を'曲げる,こじつける,拡大解釈する / 〈液体〉‘を'『こす』;(液体から)〈固形分〉‘を'こして取る《+『out(off)』+『名』+『from』+『名』》 / 全力を尽くす,懸命に努力する / ぱんと張る / 〈C〉〈U〉『張りつめること』,張る力 / 〈C〉『筋違い』,ねんざ,くじき / 〈U〉(精神的に,極度に)緊張,重荷,過労 / 〈C〉骨のおれる仕事,激務
- 〈C〉家系,血統,種族 / 〈C〉品種 / 〈U〉《しばしばa ~》(遺伝的な)性質,体質 / 〈C〉《しばしば複数形で》《単数扱い》(音楽の)曲,一節 / 〈C〉口調,言い回し,文体
- 生まれつきの(inborn) / 近親交配による
- 緊張した;疲れた / 不自然な,わざとらしい;こじつけの
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2012/10/25 15:19:36」(JST)
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Inbred strains (also called inbred lines, or for animals linear animals) are individuals of a particular species which are nearly identical to each other in genotype due to long inbreeding. Inbred strains of animals are frequently used in laboratories for experiments where for reproducibility of conclusions all the test animals should be as similar as possible. However, for some experiments, genetic diversity in the test population may be desired. Thus outbred strains of most laboratory animals are also available.
Certain plants including the genetic model organism Arabidopsis thaliana naturally self pollinates, which makes it quite easy to create inbred strains in the laboratory (other plants, including important genetic models such as Maize require transfer of pollen from one flower to another). For most animals, the usual procedure is mating of brother-sister pairs for 20 generations which will result in lines that are roughly 98% genetically identical. For most purposes this is sufficient to be considered an inbred strain (compare to identical twins or clones which are 100% genetically identical).
See also:
- Backcrossing
- Linebreeding
- Recombinant inbred strain
The most well-known lines of laboratory animals are:
Rats
- Wistar as a generic name for inbred strains such as Wistar-Kyoto, developed from the Wistar outbred strains
- Sprague-Dawley
- Long-Evans
Mice
- C57BL/6
- DBA/2
- BALB/c
- A/J
- C3H
Guinea pig
UpToDate Contents
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English Journal
- Prenatal stress and adult drug-seeking behavior: interactions with genes and relation to nondrug-related behavior.
- Kippin TE1, Campbell JC, Ploense K, Knight CP, Bagley J.
- Advances in neurobiology.Adv Neurobiol.2015;10:75-100. doi: 10.1007/978-1-4939-1372-5_5.
- Addiction inflicts large personal, social, and economic burdens, yet its etiology is poorly defined and effective treatments are lacking. As with other neuropsychiatric disorders, addiction is characterized by a core set of symptoms and behaviors that are believed to be influenced by complex gene-en
- PMID 25287537
- Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects.
- Yoo HS1, Bradford BU, Kosyk O, Uehara T, Shymonyak S, Collins LB, Bodnar WM, Ball LM, Gold A, Rusyn I.
- Journal of toxicology and environmental health. Part A.J Toxicol Environ Health A.2015;78(1):32-49. doi: 10.1080/15287394.2015.958418.
- Trichloroethylene (TCE) is a well-known environmental and occupational toxicant that is classified as carcinogenic to humans based on the epidemiological evidence of an association with higher risk of renal-cell carcinoma. A number of scientific issues critical for assessing human health risks from
- PMID 25424545
- Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: liver effects.
- Yoo HS1, Bradford BU, Kosyk O, Shymonyak S, Uehara T, Collins LB, Bodnar WM, Ball LM, Gold A, Rusyn I.
- Journal of toxicology and environmental health. Part A.J Toxicol Environ Health A.2015;78(1):15-31. doi: 10.1080/15287394.2015.958417.
- Trichloroethylene (TCE) is a widely used organic solvent. Although TCE is classified as carcinogenic to humans, substantial gaps remain in our understanding of interindividual variability in TCE metabolism and toxicity, especially in the liver. A hypothesis was tested that amounts of oxidative metab
- PMID 25424544
Japanese Journal
- Factors underlying natural variation in body pigmentation of Drosophila melanogaster
- Stress-reactive rats (high-avoidance female rats) have a shorter lifespan than stress-nonreactive rats (low-avoidance female rats)
- Response, use and habituation to a mouse house in C57BL/6J and BALB/c mice
Related Links
- A recombinant inbred strain (or recombinant inbred line) is an organism with chromosomes that incorporate an essentially permanent set of recombination events between chromosomes inherited from two or more inbred strains. F1 ...
- Value of inbred strains and strain panels Inbred strains These well-characterized, genetically uniform mouse strains can be used for a wide variety research. The large number of inbred mouse strains mimics the genetic variability ...
Related Pictures
★リンクテーブル★
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- 英
- clone、inbred strain、inbred line、pure line、inbred
- 関
- 近交系、クローニング、クローン、クローン化、同系交配、同系繁殖、栄養系、純株
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- 英
- inbred line、inbred strain、inbred
- 同
- 近交動物
- 関
- 純系、同系交配、同系繁殖
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- 関
- clone、inbred、inbred strain、pure line
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- 関
- clone、inbred、inbred line、inbred strain
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- 関
- inbred mouse strain、inbred strain of mouse
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- 強く引っ張られること、張りつめ。極度の緊張、重圧、重荷。酷使。過労
- 懸命の努力、奮闘。
- ひずみ、変形。ひずみ度。筋違い、捻挫。損傷
- 引っ張る(at)。(緊張する、(便所で)力む。(~に抗して)力を込める(against)。(歌手が)声を振り絞る
- Treatment with bed rest, head elevation, and avoidance of straining is the first step.(外リンパ瘻)(治療の第一歩はベットでの安静、頭部挙上、および力むことを回避することである)
- 懸命につとめる、非常に骨を折る(after, todo)。逡巡する(at)
- She is straining to take a breath but can only mouth the phrase: "I can't br-" brefore collapsing.
- ねじれる、狂いを生ずる
- 漉される、しみ通る/出る、したたる
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- 関
- clone、inbred line、inbred strain、inbreed、inbreeding、pure line
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