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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/07/02 09:18:33」(JST)
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Cefatrizine
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Clinical data |
AHFS/Drugs.com |
International Drug Names |
Routes of
administration |
Oral |
ATC code |
|
Identifiers |
IUPAC name
- (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]
amino}-8-oxo-3-[(1H-1,2,3-triazol-4-ylsulfanyl)methyl]-
5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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CAS Number |
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PubChem CID |
|
ChemSpider |
|
UNII |
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KEGG |
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ChEBI |
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ChEMBL |
|
ECHA InfoCard |
100.052.096 |
Chemical and physical data |
Formula |
C18H18N6O5S2 |
Molar mass |
462.505 g/mol |
3D model (Jmol) |
|
SMILES
-
O=C2N1/C(=C(\CS[C@@H]1[C@@H]2NC(=O)[C@@H](c3ccc(O)cc3)N)CSc4nnnc4)C(=O)O
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InChI
-
InChI=1S/C18H18N6O5S2/c19-12(8-1-3-10(25)4-2-8)15(26)21-13-16(27)24-14(18(28)29)9(7-31-17(13)24)6-30-11-5-20-23-22-11/h1-5,12-13,17,25H,6-7,19H2,(H,21,26)(H,28,29)(H,20,22,23)/t12-,13-,17-/m1/s1 Y
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Key:UOCJDOLVGGIYIQ-PBFPGSCMSA-N Y
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NY (what is this?) (verify) |
Cefatrizine is a broad-spectrum cephalosporin antibiotic.
References
Antibiotics active on the cell wall and envelope (J01C-J01D)
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Intracellular |
- Inhibit peptidoglycan subunit synthesis and transport: NAM synthesis inhibition (Fosfomycin)
- DADAL/AR inhibitors (Cycloserine)
- bactoprenol inhibitors (Bacitracin)
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Glycopeptide |
- Inhibit PG chain elongation: Vancomycin# (Oritavancin
- Telavancin)
- Teicoplanin (Dalbavancin)
- Ramoplanin
|
β-lactams/
(inhibit PBP
cross-links) |
|
Other |
- polymyxins/detergent
- depolarizing
- Hydrolyze NAM-NAG
- Tyrothricin
- Isoniazid#
- Teixobactin
|
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
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UpToDate Contents
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English Journal
- Pathogen incidence and antibiotic resistance patterns of catheter-associated urinary tract infection in children.
- Bi XC, Zhang B, Ye YK, He HC, Han ZD, Dai QS, Liang YX, Zeng GH, Wang YS, Chen QB, Zhong WD.SourceSouthern Medical University, Guangzhou, China.
- Journal of chemotherapy (Florence, Italy).2009 Dec;21(6):661-5.
- The aim of this study was to characterize the pathogens and their antibiotic susceptibilities in children with catheter-associated urinary tract infection (CAUTI) in order to optimize empirical antibiotic therapy and prophylaxis. from 2001 to 2006, 895 children with an indwelling catheter from 3 hos
- PMID 20071290
- In vitro activity of cefadroxil, cephalexin, cefatrizine and cefpirome in presence of essential and trace elements.
- Sultana N, Arayne MS.SourceDepartment of Pharmaceutical Chemistry, Research Institute of Pharmaceutical Sciences, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.
- Pakistan journal of pharmaceutical sciences.2007 Oct;20(4):305-10.
- Evidences supporting the introduction of metallic elements in several biological processes are rapidly accumulating. Likewise, many drugs possess modified toxicological and pharmacological properties when in the form of metal complexes. In order to ascertain the role of various essential and trace e
- PMID 17604254
Japanese Journal
- セファトリジンプロピレングリコール (セフラコール <SUP>®</SUP> ドライシロツプ) によるアナフィラキシーショックの1例
- Dose Dependency in the Gastrointestinal Absorption of Cefatrizine : Correlation between in Vivo and in Situ
- ラットにおける非線形消化管吸収の生理機構論的解析 : in vitro-in vivo 相関の検討および吸収予測への応用
- 薬物動態 = Xenobiotic metabolism and disposition 12, 70-71, 1997-10-09
- NAID 10007531424
Related Links
- Cefatrizine is a medicine available in a number of countries worldwide. A list of US medications equivalent to Cefatrizine is available on the Drugs.com website. ... Scheme Prop.INN ATC (Anatomical Therapeutic Chemical ...
- Cefatrizine [CFT] セファトリジン, セフェム系 1. 商品名 後発品 後発品2件 を表示 セフラコールDS10%/セフラコールDS25% 【沢井製薬】 パラントシンドライシロップ250 【東和薬品】 2. 日本における発売年 1980(昭和55)年 3. 特長 ...
Related Pictures
★リンクテーブル★
[★]
- 英
- cefatrizine CFT、propylene glycolate cefatrizine
- ラ
- cefatrizinum
- 関
- セファトリジンプロピレングリコール
[★]
セファトリジン cefatrizine
[★]
- 関
- cefatrizine