剥脱性皮膚炎
WordNet
- inflammation of the skin; skin becomes itchy and may develop blisters
PrepTutorEJDIC
- 皮膚炎
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/02/07 06:15:04」(JST)
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| Erythroderma |
| Classification and external resources |
| Specialty |
dermatology |
| ICD-10 |
L26, L53.9 |
| ICD-9-CM |
695.9 |
| DiseasesDB |
29735 |
| MedlinePlus |
001610 |
| eMedicine |
derm/142 |
| MeSH |
D003873 |
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[edit on Wikidata]
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Erythroderma (also known as "Exfoliative dermatitis," "Dermatitis exfoliativa) is an inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface.[1][2]
In ICD-10, a distinction is made between "exfoliative dermatitis" at L26, and "erythroderma" at L53.9.
Contents
- 1 Causes
- 2 Treatment
- 3 History
- 4 References
Causes
Erythroderma is generalized exfoliative dermatitis, which involves 90% or more of the patient's skin.[3] The most common cause of erythroderma is exacerbation of an underlying skin disease, such as psoriasis, contact dermatitis, seborrheic dermatitis, lichen planus, pityriasis rubra pilaris or a drug reaction. Primary erythroderma is less frequent and is usually seen in cases of cutaneous T-cell lymphoma, in particular in Sézary's disease.[4]
The most common causes of exfoliative dermatitis are best remembered by the mnemonic device ID-SCALP.[3] The causes and their frequencies are as follows:
- Idiopathic - 30%
- Drug allergy - 28%
- Seborrheic dermatitis - 2%
- Contact dermatitis - 3%
- Atopic dermatitis - 10%
- Lymphoma and leukemia - 14%
- Psoriasis - 8%
Differential diagnosis in patients with erythroderma may be difficult.[citation needed]
Treatment
The treatment is dependent on the cause.[citation needed] Topical steroids are the primary category of medications used to treat exfoliative dermatitis (ED). A sedative antihistamine may be a useful adjunct for pruritic patients, since it helps patients to sleep at night, thus limiting nocturnal scratching and excoriations. Antimicrobial agents often are used if an infection is suspected to be precipitating or complicating exfoliative dermatitis. Other drugs specifically indicated for management of underlying etiology of exfoliative dermatitis may be necessary.[citation needed]
History
The classification of exfoliative dermatitis into Wilson-Brocq (chronic relapsing), Hebra or pityriasis rubra (progressive), and Savill (self-limited) types may have had historical value, but it currently lacks pathophysiologic or clinical utility.[1]
References
- ^ a b Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. p. 436. ISBN 0-07-138076-0.
- ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. p. 125. ISBN 0-7216-2921-0.
- ^ a b Erythroderma (Generalized Exfoliative Dermatitis) at eMedicine
- ^ http://books.google.com/books?id=WgkZH4Hse6gC&pg=PA40&dq=erythroderma[full citation needed]
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Urticaria and erythema (L50–L54, 695, 708)
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Urticaria
(acute/chronic) |
| Allergic urticaria |
- Urticarial allergic eruption
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| Physical urticaria |
- Cold urticaria
- Primary cold contact urticaria
- Secondary cold contact urticaria
- Reflex cold urticaria
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- Heat urticaria
- Localized heat contact urticaria
- Solar urticaria
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- Dermatographic urticaria
- Vibratory angioedema
- Pressure urticaria
- Cholinergic urticaria
- Aquagenic urticaria
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| Other urticaria |
- Acquired C1 esterase inhibitor deficiency
- Adrenergic urticaria
- Exercise urticaria
- Galvanic urticaria
- Schnitzler syndrome
- Urticaria-like follicular mucinosis
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| Angioedema |
- Episodic angioedema with eosinophilia
- Hereditary angioedema
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| Erythema |
Erythema multiforme/
drug eruption |
- Erythema multiforme minor
- Erythema multiforme major (Stevens–Johnson syndrome, Toxic epidermal necrolysis)
- panniculitis (Erythema nodosum)
- Acute generalized exanthematous pustulosis
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| Figurate erythema |
- Erythema annulare centrifugum
- Erythema marginatum
- Erythema migrans
- Erythema gyratum repens
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| Other erythema |
- Necrolytic migratory erythema
- Erythema toxicum
- Erythroderma
- Palmar erythema
- Generalized erythema
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Index of skin
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| Description |
- Anatomy
- Physiology
- Development
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| Disease |
- Infections
- Vesiculobullous
- Dermatitis and eczema
- Papulosquamous
- Urticaria and erythema
- Radiation-related
- Pigmentation
- Mucinoses
- Keratosis, ulcer, atrophy, and necrobiosis
- Vasculitis
- Fat
- Neutrophilic and eosinophilic
- Congenital
- Neoplasms and cancer
- nevi and melanomas
- epidermis
- dermis
- Symptoms and signs
- Terminology
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| Treatment |
- Procedures
- Drugs
- antibiotics
- disinfectants
- emollients and protectives
- itch
- psoriasis
- other
- Wound and ulcer
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Papulosquamous disorders (L40–L45, 696–697)
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| Psoriasis |
| Pustular |
- Generalized pustular psoriasis (Impetigo herpetiformis)
- Acropustulosis/Pustulosis palmaris et plantaris (Pustular bacterid)
- Annular pustular psoriasis
- Localized pustular psoriasis
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| Other |
- Guttate psoriasis
- Psoriatic arthritis
- Psoriatic erythroderma
- Drug-induced psoriasis
- Inverse psoriasis
- Napkin psoriasis
- Seborrheic-like psoriasis
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| Parapsoriasis |
- Pityriasis lichenoides (Pityriasis lichenoides et varioliformis acuta, Pityriasis lichenoides chronica)
- Lymphomatoid papulosis
- Small plaque parapsoriasis (Digitate dermatosis, Xanthoerythrodermia perstans)
- Large plaque parapsoriasis (Retiform parapsoriasis)
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| Other pityriasis |
- Pityriasis rosea
- Pityriasis rubra pilaris
- Pityriasis rotunda
- Pityriasis amiantacea
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| Other lichenoid |
| Lichen planus |
- configuration
- morphology
- Hypertrophic
- Atrophic
- Bullous
- Ulcerative
- Actinic
- Pigmented
- site
- Mucosal
- Nails
- Peno-ginival
- Vulvovaginal
- overlap synromes
- with lichen sclerosus
- with lupus erythematosis
- other:
- Hepatitis-associated lichen planus
- Lichen planus pemphigoides
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| Other |
- Lichen nitidus
- Lichen striatus
- Lichen ruber moniliformis
- Gianotti–Crosti syndrome
- Erythema dyschromicum perstans
- Idiopathic eruptive macular pigmentation
- Keratosis lichenoides chronica
- Kraurosis vulvae
- Lichen sclerosus
- Lichenoid dermatitis
- Lichenoid reaction of graft-versus-host disease
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Index of skin
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| Description |
- Anatomy
- Physiology
- Development
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| Disease |
- Infections
- Vesiculobullous
- Dermatitis and eczema
- Papulosquamous
- Urticaria and erythema
- Radiation-related
- Pigmentation
- Mucinoses
- Keratosis, ulcer, atrophy, and necrobiosis
- Vasculitis
- Fat
- Neutrophilic and eosinophilic
- Congenital
- Neoplasms and cancer
- nevi and melanomas
- epidermis
- dermis
- Symptoms and signs
- Terminology
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| Treatment |
- Procedures
- Drugs
- antibiotics
- disinfectants
- emollients and protectives
- itch
- psoriasis
- other
- Wound and ulcer
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UpToDate Contents
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English Journal
- Discovery in genetic skin disease: the impact of high throughput genetic technologies.
- Maruthappu T1, Scott CA2, Kelsell DP3.
- Genes.Genes (Basel).2014 Aug 4;5(3):615-34. doi: 10.3390/genes5030615.
- The last decade has seen considerable advances in our understanding of the genetic basis of skin disease, as a consequence of high throughput sequencing technologies including next generation sequencing and whole exome sequencing. We have now determined the genes underlying several monogenic disease
- PMID 25093584
- Delayed Onset of the Jarisch-Herxheimer Reaction in Doxycycline-Treated Disease: A Case Report and Review of its Histopathology and Implications for Pathogenesis.
- Kadam P1, Gregory NA, Zelger B, Carlson JA.
- The American Journal of dermatopathology.Am J Dermatopathol.2014 Jul 15. [Epub ahead of print]
- : The Jarisch-Herxheimer reaction (JHR) is a transient inflammatory syndrome triggered hours after the start of antibiotic treatment of spirochete infections, namely syphilis. Clinically, JHR manifests as an abrupt onset of constitutional symptoms and exacerbation of cutaneous lesions that resolve w
- PMID 25033009
- Lichenoid drug reaction to isoniazid presenting as exfoliative dermatitis in a patient with acquired immunodeficiency syndrome.
- Thakur B1, Verma S2, Mishra J3.
- International journal of STD & AIDS.Int J STD AIDS.2014 Jul 10. pii: 0956462414543123. [Epub ahead of print]
- Human immunodeficiency virus-infected patients are at increased risk of drug reaction because of immune dysregulation and multiple drug intake. Lichenoid drug reactions to isoniazid have been reported previously in the literature. However, for lichenoid drug reaction to isoniazid to be so extensive
- PMID 25013221
Japanese Journal
- Human Herpesvirus 6 Reactivation in Trichloroethylene-exposed Workers Suffering from Generalized Skin Disorders Accompanied by Hepatic Dysfunction
- HUANG Hanlin,KAMIJIMA Michihiro,WANG Hailan,LI Senhua,YOSHIKAWA Tetsushi,LAI Guanchao,HUANG Zhenlie,LIU Huifang,CHEN Jiabin,TAKEUCHI Yasuhiro,NAKAJIMA Tamie,LI Laiyu
- Journal of occupational health 48(6), 417-423, 2006-11
- … Thirty-six cases (59%) showed exfoliative dermatitis, 17 (28%) erythema multiforme, 4 (7%) Stevens-Johnson syndrome, and 4 (7%) toxic epidermal necrolysis. …
- NAID 110004863655
- Erythroderma/exfoliative dermatitis : a synopsis
Related Links
- Exfoliative dermatitis is widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss. Causes This condition may occur in severe cases of many common skin conditions, such as eczema ...
- Exfoliative dermatitis, or erythroderma, is an erythematous, scaly dermatitis involving most, if not all, of the skin. See the image below. ... The pathophysiologic processes resulting in exfoliative dermatitis vary with the ...
Related Pictures
★リンクテーブル★
[★]
- 英
- erythroderma
- 同
- 剥脱性皮膚炎 exfoliative dermatitis
定義
- (1)全身(体表の80%以上)の持続性の炎症性発赤(潮紅)し、健常部皮膚を殆ど残さず、(2)粃糠様・落葉状の落屑が持続する病態
原因
起こしやすい疾患 (2009 CBT QB2 p.116)
- (%)は紅皮症に占める割合
起こしうる疾患 (NDE.122)
[★]
- 英
- exfoliative dermatitis
- 同
- 剥離性皮膚炎
- 関
- 紅皮症、
[show details]
[★]
- 関
- excoriating