depolarizing neuromuscular blocker

脱分極性筋弛緩薬

WordNet

1. a three-dimensional shape with six square or rectangular sides (同)cube
2. (computer science) a sector or group of sectors that function as the smallest data unit permitted; "since blocks are often defined as a single sector, the terms `block and `sector are sometimes used interchangeably"
3. support, secure, or raise with a block; "block a plate for printing"; "block the wheels of a car"
4. a solid piece of something (usually having flat rectangular sides); "the pyramids were built with large stone blocks"
5. housing in a large building that is divided into separate units; "there is a block of classrooms in the west wing"
6. a rectangular area in a city surrounded by streets and usually containing several buildings; "he lives in the next block" (同)city block
7. an inability to remember or think of something you normally can do; often caused by emotional tension; "I knew his name perfectly well but I had a temporary block" (同)mental_block
8. a number or quantity of related things dealt with as a unit; "he reserved a large block of seats"; "he held a large block of the companys stock"
9. interrupt the normal function of by means of anesthesia; "block a nerve"; "block a muscle"
10. run on a block system; "block trains"
11. shape by using a block; "Block a hat"; "block a garment"
12. shape into a block or blocks; "block the graphs so one can see the results clearly"
13. stamp or emboss a title or design on a book with a block; "block the book cover"
14. a class of drugs that inhibit (block) some biological process (同)blocking_agent
15. a football player whose responsibility is to block players attempting to stop an offensive play
16. affecting or characteristic of both neural and muscular tissue

PrepTutorEJDIC

1. (木・石などの,通例平らな面のある)『かたまり』 / 《米》(四団を街路に囲まれた)『区画』,街区 / 街区の1辺の距離(一般に40メートル前後) / 《英》ブロック(アパート・事務所・商店などに区切られている大きな建物) / 『妨害物』,障害物(obstacle);(障害によって生じた)停滞,渋滞 / 台木,台(まないた・肉切り台・まき割り台・せり売り台・帽子の木型など);《the~》炭頭台 / (特にアメリカンフットボールで)ブロック(相手の選手の突進を阻止する) / 滑車(pulley) / (座席券・株券などの)一組《+『of』+『名』》 / 〈通路など〉'を'『ふさぐ』,〈通行・進行など〉'を'妨げる / 〈帽子など〉の型取りをする / (特にアメリカンフットボールで)〈相手選手の突進〉'を'ブロックする;(ボクシングで)〈相手のパンチ〉'を'ブロックする

UpToDate Contents

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• 1. 重症患者における神経筋遮断剤の使用 use of neuromuscular blocking medications in critically ill patients
• 2. 手術室外で成人に迅速導入気管挿管を行う際に用いる神経筋遮断薬（NMBA） neuromuscular blocking agents nmba for rapid sequence intubation in adults outside the operating room
• 3. 全身麻酔：導入 general anesthesia induction
• 4. 重症筋無力症患者に対する麻酔 anesthesia for the patient with myasthenia gravis
• 5. Rapid sequence intubation (RSI) outside of the operating room in children: Medications for sedation and paralysis

English Journal

• Efficacy and safety of sugammadex versus neostigmine in reversing neuromuscular blockade in adults.

• Hristovska AM1, Duch P, Allingstrup M, Afshari A.
• The Cochrane database of systematic reviews.Cochrane Database Syst Rev.2017 Aug 14;8:CD012763. doi: 10.1002/14651858.CD012763.
• PMID 28806470

• Avoidance versus use of neuromuscular blocking agents for improving conditions during tracheal intubation or direct laryngoscopy in adults and adolescents.

• Lundstrøm LH1, Duez CH2, Nørskov AK1, Rosenstock CV1, Thomsen JL3, Møller AM4, Strande S5, Wetterslev J6.
• The Cochrane database of systematic reviews.Cochrane Database Syst Rev.2017 May 17;5:CD009237. doi: 10.1002/14651858.CD009237.pub2.
• PMID 28513831

• Succinylcholine for Emergency Airway Rescue in Class B Ambulatory Facilities: The Society for Ambulatory Anesthesia Position Statement.

• Joshi GP1, Desai MS, Gayer S, Vila H Jr; Society for Ambulatory Anesthesia (SAMBA).
• Anesthesia and analgesia.Anesth Analg.2017 May;124(5):1447-1449. doi: 10.1213/ANE.0000000000001682.
• PMID 27984222

Japanese Journal

• Latent myasthenia gravis revealed by protracted postoperative effect of non-depolarizing neuromuscular blockade

• Journal of anesthesia 26(6), 953-954, 2012-12-20
• NAID 10031147442

• 種々の病態での神経筋接合部の変化と筋弛緩モニタリングの留意点

• 日本臨床麻酔学会誌 = The Journal of Japan Society for Clinical Anesthesia 29(1), 23-34, 2009-01-15
• NAID 10023975352

• 種々の病態での神経筋接合部の変化と筋弛緩モニタリングの留意点

• 日本臨床麻酔学会誌 29(1), 23-34, 2009
• NAID 130004449815

Related Links

• Depolarizing Neuromuscular Blocker - Welcome || Getting started

... Depolarizing Neuromuscular Blocker Mechanism of Action: In the motor endplate it combines with nicotinic receptors to produce depolarization which can be observed as uncontrolled focal muscle contractions ...

• Suxamethonium -Depolarizing Neuromuscular Blocker | howMed

Suxamethonium is the only drug used in the category of depolarizing neuromuscular blockers and is synthetic, consisting of 2 molecules of acetyl choline joined together. Mechanism of Action It binds to post-synaptic nicotinic ...

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★リンクテーブル★

リンク元	「脱分極性筋弛緩薬」「脱分極性神経筋遮断薬」
拡張検索	「non-depolarizing neuromuscular blocker」
関連記事	「block」「blocker」「neuromuscular blocker」

「脱分極性筋弛緩薬」

　　[★]

英

depolarizing muscle relaxant

同

脱分極性神経筋遮断薬 depolarizing neuromuscular blocker、脱分極性神経筋接合部遮断薬 depolarizing neuromuscular junction blockingagent

非競合的筋弛緩薬、非競合的神経筋遮断薬、脱分極性神経筋遮断薬　←この使われ方は一般的ではない

関

競合的筋弛緩薬

• スキサメトニウム suxamethonium
• デカメトニウム decamethonium

「脱分極性神経筋遮断薬」

　　[★]

英

neuromuscular depolarizing agent, depolarizing neuromuscular blocker

関

脱分極性筋弛緩薬

「non-depolarizing neuromuscular blocker」

　　[★] 非脱分極性筋弛緩薬

「block」

　　[★]

• n.

• 遮断、塊、ブロック

• v.

• 遮断する、ブロックする、封鎖する、阻止する

関

blockade、blockage、deter、inhibit、inhibition、lump、prevent、prevention、repress、repression、seal、turn off

　 　 　 　 　 　 　 　 　 　 　 　 　 　

「blocker」

　　[★]

• n.

• 遮断薬、ブロッカー、遮断剤、阻害薬

関

antagonist、blocking agent、inhibitor

　 　

「neuromuscular blocker」

　　[★]

• 神経筋遮断薬

関

neuromuscular blocking agent、neuromuscular blocking drug