赤血球沈降速度
WordNet
- be worthy of or have a certain rating; "This bond rates highly"
- amount of a charge or payment relative to some basis; "a 10-minute phone call at that rate would cost $5" (同)charge per unit
- a magnitude or frequency relative to a time unit; "they traveled at a rate of 55 miles per hour"; "the rate of change was faster than expected"
- a quantity or amount or measure considered as a proportion of another quantity or amount or measure; "the literacy rate"; "the retention rate"; "the dropout rate"
- assign a rank or rating to; "how would you rank these students?"; "The restaurant is rated highly in the food guide" (同)rank, range, order, grade, place
- estimate the value of; "How would you rate his chances to become President?"; "Gold was rated highly among the Romans" (同)value
- give (hair) the appearance of being fuller by using a rat
- a pad (usually made of hair) worn as part of a womans coiffure
- any of various long-tailed rodents similar to but larger than a mouse
- catch rats, especially with dogs
- desert ones party or group of friends, for example, for ones personal advantage
- employ scabs or strike breakers in
- smear with blood, as in a hunting initiation rite, where the face of a person is smeared with the blood of the kill
- temperament or disposition; "a person of hot blood"
- people viewed as members of a group; "we need more young blood in this organization"
- the fluid (red in vertebrates) that is pumped through the body by the heart and contains plasma, blood cells, and platelets; "blood carries oxygen and nutrients to the tissues and carries away waste products"; "the ancients believed that blood was the sea
- standing or position on a scale
PrepTutorEJDIC
- 〈C〉『割合』,『率』 / 〈C〉《the~,a~》『速度』(speed),進度 / 〈C〉『値段』,『相場』;料金 / 〈U〉等級(class),(…)等 / 《複数形ぃ》《英》地方税 / (…の金額に)…‘の'『値段を決める』,見積もる《+『名』+『at』+『名』》 / …‘を'『評価する』,みなす / 《米話》…‘に'値する,‘の'価値がある / 『評価される』;みなされる
- …‘を'どなりつける
- 『ネズミ』 / ひきょう者,裏切り者 / ネズミをつかまえる / 《話》(人を)裏切る,密告する《+『on』+『名』〈人〉》
- 『血』,『血』液 / 流血(bloodshed);殺人 / 気質,気性,血気,血潮 / 『血統』,血縁(kinship);生まれ,家柄;《the~》王家の血統 / (人種・出身国の)系 / 〈人〉‘に'初めての経験をさせる / 〈猟犬〉‘に'初めて獲物を血を味わわせる
- 〈C〉〈U〉(品質・技量などによる)格づけ,評価 / 〈C〉(個人・会社の経済的な)信用度 / 〈C〉(トン・馬力による)(船舶・車)の等級 / 〈C〉(テレビ・ラジオの)視聴率
- 沈殿,堆積;沈殿(堆積)作用
UpToDate Contents
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English Journal
- Interleukin-6 is prone to be a candidate biomarker for predicting incomplete and IVIG nonresponsive Kawasaki disease rather than coronary artery aneurysm.
- Wu Y, Liu FF, Xu Y, Wang JJ, Samadli S, Wu YF, Liu HH, Chen WX, Luo HH, Zhang DD, Wei W, Hu P.
- Clinical and experimental medicine. 2019 May;19(2)173-181.
- Kawasaki disease (KD) is an acute, systemic vasculitis and occurs mainly in childhood. Interleukin-6 (IL-6) is a pleiotropic cytokine synthesized predominantly by neutrophils and monocytes/macrophages and plays an important role in systemic inflammatory disease. However, a little information is curr
- PMID 30617865
- Role of routine blood tests for predicting clinical outcomes in osteosarcoma patients.
- Jettoo P, Tan G, Gerrand CH, Rankin KS.
- Journal of orthopaedic surgery (Hong Kong). ;27(2)2309499019838293.
- This retrospective cohort study aimed to investigate whether simple routine blood tests at presentation (C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alkaline phosphatase and albumin) predict survival in patients with osteosarcoma. Between January 1998 and February 2015, 134 patie
- PMID 30909848
- Kaya HE, Kerimoğlu Ü.
- Radiology. 2019 May;291(2)539-541.
- History A 20-year old woman living in Turkey presented with a 3-month history of lower back pain. She had no medical history of note and was taking no medications. Complete blood count, C-reactive protein level, sedimentation rate, and creatinine, alanine aminotransferase, and aspartate aminotransfe
- PMID 30998447
Japanese Journal
- Sonoyama Hiroki,Oshima Naoki,Moriyama Ichiro,Yuki Takafumi,Onishi Koji,Kinoshita Yoshikazu,Kawashima Kousaku,Ishihara Shunji,Kotani Satoshi,Fukuba Nobuhiko,Oka Akihiko,Kusunoki Ryusaku,Tada Yasumasa,Mishima Yoshiyuki
- Journal of Clinical Biochemistry and Nutrition 64(3), 265-270, 2019
- … In the present study, we investigated the correlation of fecal calprotectin level with endoscopic findings as compared to blood biomarkers according to ulcerative colitis disease type. … Fecal calprotectin as well as the blood biomarkers: C-reactive protein (CRP), white blood count (WBC), erythrocyte sedimentation rate (ESR), hemoglobin, platelet count (PLT), and serum albumin (Alb) were measured in patients who underwent a complete colonoscopy. …
- NAID 130007641427
- Rare Simultaneous Left and Right-Sided Native Valve Infective Endocarditis Caused by Rare Bacterium
- Pan Jian-Hong
- International Heart Journal 60(2), 474-476, 2019
- … Laboratory evaluation revealed an elevated erythrocyte sedimentation rate and C-reactive protein level, and high fasting blood glucose. … Blood culture was positive for S. …
- NAID 130007617005
- Study of correlation of level of expression of Wnt signaling pathway inhibitors sclerostin and dickkopf-1 with disease activity and severity in rheumatoid arthritis patients
- Singh Anup,Gupta Manish Kumar,Mishra Surendra Pratap
- Drug Discoveries & Therapeutics 13(1), 22-27, 2019
- … Patients were evaluated clinically and investigated with routine blood tests along with rheumatoid factor (RF), anti-citrullinated protein antibody (anti-CCP<sub>2</sub>), radiographs and bone mineral density (BMD). … Serum sclerostin showed significant correlation with disease activity scores (DAS score and MHAQ score), erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) level. …
- NAID 130007615040
Related Links
- Erythrocyte Sedimentation Rate Definition The erythrocyte sedimentation rate (ESR), or sedimentation rate (sed rate), is a measure of the settling of red blood cells in a tube of blood during one hour. The rate is an indication of ...
- Hi. The SED rate or Sedimentation rate measures the speed at which red blood cells settle at the bottom of a test tube. It is a test which is not specific for diagnosing lymphoma. A high sedimentation rate can be found in any ...
Related Pictures
★リンクテーブル★
[★]
- sedimentation
- 英
- erythrocyte sedimentation rate, ESR
- 同
- 赤沈, 血沈 blood sedimentation rate, BSR
- 関
- [[]]
概念
- 抗凝固剤を加えた全血中の赤血球が自然凝集により沈降する速度。
- 自然凝集は正電荷または負電荷をもつ血漿蛋白質のバランスを反映する。
- 炎症により正電荷をもつ蛋白質が増加し、負電荷をもつ蛋白質が減少するので、炎症のマーカーとして用いられている。
- 大きいほど赤血球同士が凝集して沈降する速度が高まっていることを示す
基準値
- 一時間値で評価
- 全血+クエン酸(臨床検査法提要第32版 p.1790)
- M:2-10 mm
- F:3-15 mm
- 男性で10mm/h以上、女性で15mm/h以上で赤沈促進と判定
赤沈の起こるメカニズム (OLM.138)
- 負に帯電:赤血球、アルブミン → 増加により赤沈↓
- 正に帯電:αグロブリン(α1-グロブリン)、γグロブリン、フィブリノゲン → 増加により赤沈↑
- 赤血球は負に帯電しており、電気的反発力により凝集塊の形成が妨げられている。赤血球数が増加すると、赤血球同士が反発しあうことで赤沈が遅れ、赤沈が減少する。
- アルブミンは負に帯電しており、赤血球同士を反発させることで凝集を妨げる。これにより赤沈が遅れ、赤沈が減少する。
- 正に帯電した物質の存在により赤血球の電荷が打ち消され、赤血球の凝集が促進される。これにより赤沈が増加する。
測定方法 (OLM.137)
- Westergren法
- 3.28%(109mmol/l)クエン酸ナトリウム(Na3C6H5O7・H2O)液と血液を1:4の割合に混合し、内径2.55±0.15mm、前腸300±1.5mmのWestergren肝に吸い上げ、これを正確に垂直に立てて18-25℃に整地し、1時間後に赤沈地を記録する。
赤沈値の解釈 (OLM.138)
赤沈の亢進
- 1. 技術的間違い:ピペットを傾斜させた場合
- 2. 赤血球数の減少
- 血液希釈状態
- 循環血漿量の増加:妊娠
- 貧血
- 3. フィブリノゲン・αグロブリンの増加
- 妊娠
- 炎症性疾患:感染症、膠原病活動期、悪性腫瘍など
- ストレス:大手術、外傷など
赤沈亢進とCRP陰性
- 急性炎症回復期
- 貧血
- ネフローゼ症候群
- 妊娠
- 多発性骨髄腫 → CRPが陰性かどうかは疑わしい。典型例や軽症例、病初期では陰性ということか。成書にはCRPについての記載はない(HIM WCH)。進行期にはCRP陽性となる(参考1,2)。
- 慢性甲状腺炎 → 自己抗体の増加
- 原発性マクログロブリン血症
- 高フィブリノゲン血症
赤沈の遅延
参考
- http://ganjoho.jp/public/cancer/data/myeloma_diagnosis.html
- http://www.med.osaka-cu.ac.jp/labmed/page086.html
[★]
- (全体に対する部分などの割合を示す)率 ⇔ (率を率で除すような比 ratioとは区別するでしょう)
- 格付けされる、等級に分けられる
- 影響力がある、重要な地位にある
- ~を値踏みする、~の価格を査定する
- (~の重要性や価値を)評価する
- (性能などによって)~を格付けする(等級に分ける)
- (金融)(不動産の)課税額を決める
- ~に値する、~の価値がある
[★]
- (げっ歯類)ラット、(マウスも含めての総称)ネズミ、ラットの
- 関
- laboratory rat、mouse、Norway rat、Rattus、Rattus norvegicus
[★]
- 関
- centrifugation、precipitate、precipitation、sediment
[★]
- 関
- erythrocyte sedimentation rate
[★]
- 関
- sedimentation velocity