スイート病
WordNet
- pleasing to the senses; "the sweet song of the lark"; "the sweet face of a child"
- a food rich in sugar (同)confection
- the taste experience when sugar dissolves in the mouth (同)sweetness, sugariness
- (used of wines) having a high residual sugar content; "sweet dessert wines"
- having or denoting the characteristic taste of sugar
- an impairment of health or a condition of abnormal functioning
- caused by or altered by or manifesting disease or pathology; "diseased tonsils"; "a morbid growth"; "pathologic tissue"; "pathological bodily processes" (同)morbid, pathologic, pathological
- English phonetician; one of the founders of modern phonetics (1845-1912) (同)Henry Sweet
PrepTutorEJDIC
- (砂糖のように)『甘い』;砂糖の入った / 心地よい,香りのよい,美しい,おいしい / 新鮮な,腐っていない / (性質などが)『人好きのする』,気だてのよい,優しい,親切な / (酒が)甘口の / 〈C〉《英》甘い料理,(特に)デザート / 《複数形で》《英》(ケーキ・キャンデーなどの)『砂糖菓子』(《米》candy) / 〈U〉《呼びかけで》あなた,おまえ / 《複数形で》《the ~》《文》(…の)喜び,楽しみ《+of+名》
- (体の)『病気』,疾患 / (精神・道徳などの)病気,病弊
- 女性の話術芸人 =diseur
- 病気にかかった / 病的な,不健全な(morbid)
UpToDate Contents
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English Journal
- Implication of the Bacterial Endosymbiont Rickettsia spp. in Interactions of the Whitefly Bemisia tabaci with Tomato yellow leaf curl virus.
- Kliot A1, Cilia M, Czosnek H, Ghanim M.Author information 1Department of Entomology, The Volcani Center, Bet Dagan, Israel.AbstractNumerous animal and plant viruses are transmitted by arthropod vectors in a persistent, circulative manner. Tomato yellow leaf curl virus (TYLCV) is transmitted by the sweet potato whitefly Bemisia tabaci. We report here that infection with Rickettsia spp., a facultative endosymbiont of whiteflies, altered TYLCV-B. tabaci interactions. A B. tabaci strain infected with Rickettsia acquired more TYLCV from infected plants, retained the virus longer, and exhibited nearly double the transmission efficiency compared to an uninfected B. tabaci strain with the same genetic background. Temporal and spatial antagonistic relationships were discovered between Rickettsia and TYLCV within the whitefly. In different time course experiments, the levels of virus and Rickettsia within the insect were inversely correlated. Fluorescence in situ hybridization analysis of Rickettsia-infected midguts provided evidence for niche exclusion between Rickettsia and TYLCV. In particular, high levels of the bacterium in the midgut resulted in higher virus concentrations in the filter chamber, a favored site for virus translocation along the transmission pathway, whereas low levels of Rickettsia in the midgut resulted in an even distribution of the virus. Taken together, these results indicate that Rickettsia, by infecting the midgut, increases TYLCV transmission efficacy, adding further insights into the complex association between persistent plant viruses, their insect vectors, and microorganism tenants that reside within these insects.
- Journal of virology.J Virol.2014 May;88(10):5652-60. doi: 10.1128/JVI.00071-14. Epub 2014 Mar 5.
- Numerous animal and plant viruses are transmitted by arthropod vectors in a persistent, circulative manner. Tomato yellow leaf curl virus (TYLCV) is transmitted by the sweet potato whitefly Bemisia tabaci. We report here that infection with Rickettsia spp., a facultative endosymbiont of whiteflies,
- PMID 24600010
- Transplastomic Nicotiana benthamiana plants expressing multiple defence genes encoding protease inhibitors and chitinase display broad-spectrum resistance against insects, pathogens and abiotic stresses.
- Chen PJ1, Senthilkumar R, Jane WN, He Y, Tian Z, Yeh KW.Author information 1Institute of Plant Biology, College of Life Science, National Taiwan University, Taipei, Taiwan.AbstractPlastid engineering provides several advantages for the next generation of transgenic technology, including the convenient use of transgene stacking and the generation of high expression levels of foreign proteins. With the goal of generating transplastomic plants with multiresistance against both phytopathogens and insects, a construct containing a monocistronic patterned gene stack was transformed into Nicotiana benthamiana plastids harbouring sweet potato sporamin, taro cystatin and chitinase from Paecilomyces javanicus. Transplastomic lines were screened and characterized by Southern/Northern/Western blot analysis for the confirmation of transgene integration and respective expression level. Immunogold localization analyses confirmed the high level of accumulation proteins that were specifically expressed in leaf and root plastids. Subsequent functional bioassays confirmed that the gene stacks conferred a high level of resistance against both insects and phytopathogens. Specifically, larva of Spodoptera litura and Spodoptera exigua either died or exhibited growth retardation after ingesting transplastomic plant leaves. In addition, the inhibitory effects on both leaf spot diseases caused by Alternaria alternata and soft rot disease caused by Pectobacterium carotovorum subsp. carotovorum were markedly observed. Moreover, tolerance to abiotic stresses such as salt/osmotic stress was highly enhanced. The results confirmed that the simultaneous expression of sporamin, cystatin and chitinase conferred a broad spectrum of resistance. Conversely, the expression of single transgenes was not capable of conferring such resistance. To the best of our knowledge, this is the first study to demonstrate an efficacious stacked combination of plastid-expressed defence genes which resulted in an engineered tolerance to various abiotic and biotic stresses.
- Plant biotechnology journal.Plant Biotechnol J.2014 May;12(4):503-15. doi: 10.1111/pbi.12157. Epub 2014 Jan 30.
- Plastid engineering provides several advantages for the next generation of transgenic technology, including the convenient use of transgene stacking and the generation of high expression levels of foreign proteins. With the goal of generating transplastomic plants with multiresistance against both p
- PMID 24479648
- Decreased physical activity predicts cognitive dysfunction and reduced cerebral blood flow in heart failure.
- Alosco ML1, Spitznagel MB1, Cohen R2, Raz N3, Sweet LH4, Josephson R5, Hughes J6, Rosneck J7, Gunstad J8.Author information 1Department of Psychology, Kent State University, Kent, OH, USA.2Department of Neurology, University of Florida, USA; Department of Psychiatry, University of Florida, USA; The Institute on Aging, Center for Cognitive Aging and Memory, University of Florida, USA.3Institute of Gerontology, Wayne State University, Detroit, MI, USA.4Department of Psychology, University of Georgia, Athens, USA.5University Hospitals Case Medical Center and Department of Medicine, Cleveland, OH, USA; Harrington Heart & Vascular Institute, Cleveland, OH, USA; Case Western Reserve University School of Medicine, Cleveland, OH, USA.6Department of Psychology, Kent State University, Kent, OH, USA; Cardiac Rehabilitation, Summa Health System, Akron City Hospital, Akron, OH, USA.7Cardiac Rehabilitation, Summa Health System, Akron City Hospital, Akron, OH, USA.8Department of Psychology, Kent State University, Kent, OH, USA. Electronic address: jgunstad@kent.edu.AbstractOBJECTIVE: Cognitive impairment in heart failure (HF) is believed to result from brain hypoperfusion subsequent to cardiac dysfunction. Physical inactivity is prevalent in HF and correlated with reduced cardiac and cognitive function. Yet, no longitudinal studies have examined the neurocognitive effects of physical inactivity in HF. The current study examined whether reduced physical activity increases risk for cognitive impairment and brain hypoperfusion over time in HF.
- Journal of the neurological sciences.J Neurol Sci.2014 Apr 15;339(1-2):169-75. doi: 10.1016/j.jns.2014.02.008. Epub 2014 Feb 18.
- OBJECTIVE: Cognitive impairment in heart failure (HF) is believed to result from brain hypoperfusion subsequent to cardiac dysfunction. Physical inactivity is prevalent in HF and correlated with reduced cardiac and cognitive function. Yet, no longitudinal studies have examined the neurocognitive eff
- PMID 24581672
Japanese Journal
- Possible Neuro-Sweet Disease Mimicking Brain Tumor in the Medulla Oblongata : Case Report
- AKIBA Chihiro,ESAKI Takanori,ANDO Maya,FURUYA Tsuyoshi,NODA Kazuyuki,NAKAO Yasuaki,YAMAMOTO Takuji,OKUMA Yasuyuki,MORI Kentaro
- Neurologia medico-chirurgica = 神経外科 51(2), 140-143, 2011-02-15
- … A 62-year-old male presented with a rare case of possible neuro-Sweet Disease (NSD) mimicking brain tumor in the medulla oblongata, manifesting as numbness in the bilateral upper and lower extremities, gait disturbance, dysarthria, and swallowing disturbance which gradually deteriorated over 3 months. … The preoperative diagnosis was brain tumor, such as glioma, or inflammatory disease. …
- NAID 10028105016
- 5ヵ月にわたって自発性低下, 髄膜脳炎, 高度の全身炎症所見が持続し, 脳生検にて確定診断された神経好中球病の1例
- 大江 康子,中里 良彦,石澤 圭介,出口 一郎,田村 直俊,荒木 信夫
- 臨床神経学 51(1), 21-26, 2011-01-01
- NAID 10027870420
Related Links
- 急性好中球皮膚症 Sweet disease 「概念」 真皮の好中球浸潤を特徴とする炎症性疾患。 「検査」 好中球増多、血沈促進、CRP 陽性 「症状」 三主徴(発熱、好中球増多、好中球浸潤性紅斑) 「合併症」 急性骨髄性白血病、骨髄異 ...
- Sweet syndrome (acute neutrophilic dermatosis, Sweet syndrome). Authoritative facts about the skin from the New Zealand Dermatological Society. ... Subcutaneous Sweet syndrome In subcutaneous Sweet syndrome, deeper ...
★リンクテーブル★
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- 英
- Sweet's disease, Sweet disease
- 同
- スウィート病、(国試)Sweet病、急性熱性好中球性皮膚病 acute febrile neutrophilic dermatosis、スイート症候群 Sweet syndrome Sweet's syndrome
- 関
- 好中球性皮膚症, neutrophilic dermatosis
概念
- 好中球皮膚症の原型がスイート病である。急性に発熱、好中球増多、及び好中球の浸潤による紅斑を特徴とする新しい疾患概念として1964年に記載された。(参考2)
病因
- 不明
- 特定の疾患の経過に合併しやすい:好中球の活性化が見られる疾患?
疫学
- 中年の女子に好発
- 稀な疾患。男女比=1:4 (参考2)
病理
症状
- 発熱、好中球増加、好中球湿潤性紅斑
- 上気道感染などを前駆症状とし、その数日-4週間後に発熱と共に10-25mmの境界明瞭・有痛性・暗紅色浮腫性紅斑を多発。
- 皮膚症状
- 局在:顔面、項頚部、前腕、手背
- 所見:圧痛を伴う辺縁隆起性の浮腫性紅斑。紅斑の表面は粗大顆粒状、中央・辺縁に小水疱・膿疱を伴う。
治療
- NSAIDs、ヨードカリ、コルヒチンの内服。ステロイドは重症例のみ(原疾患を隠蔽してしまうため)
- 抗菌薬無効
参考
- http://dermnetnz.org/reactions/sweets.html
- http://www.sciencephoto.com/media/262589/enlarge
- http://www.visualphotos.com/image/1x9082848/sweets_disease
- 2. [charged] 好中球性皮膚症 - uptodate [1]
- 3.
- http://www.oguradaiclinic.jp/page1845.html
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- 疾患:illnessより厳密な概念。「ある臓器に明確な障害が確認され、それによって症状が出ているとはっきり説明できる場合」 (PSY.9)
- 特定の原因、病態生理、症状、経過、予後、病理組織所見が全てそろった場合 (PSY.9)
- something that is very wrong with people's attitudes, way of life or with society.
- 関
- ail、ailment、disease entity、disorder、ill、illness、malady、sick、sickness
- disease ≠ illness ≠ disorder
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