pathologic

• adj.

• 病的な、病理的な、病態的な、病理の、病態の

関

morbid、morbidly、pathologically、pathology、pathosis

WordNet

1. any deviation from a healthy or normal condition
2. the branch of medical science that studies the causes and nature and effects of diseases
3. suggesting an unhealthy mental state; "morbid interest in death"; "morbid curiosity"
4. with respect to pathology; "pathologically interesting results"
5. in a morbid manner or to a morbid degree; "he was morbidly fascinated by dead bodies"
6. a physical condition that is caused by disease

PrepTutorEJDIC

1. 〈U〉病理学 / 〈C〉〈U〉病理,病状
2. (精神が)病的な,不健全な / 病気の,病気に関する・気味の悪い,陰気な・憂鬱な・ゾッとする

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/04/09 16:47:10」(JST)

wiki en

[Wiki en表示]

For other uses, see Pathology (disambiguation).

Pathologic
Developer(s)	Ice-Pick Lodge General Arcade (Classic HD)
Publisher(s)	CIS Buka Entertainment EU G2 Games WW Gambitious Digital Entertainment (Classic HD) WW Devolver Digital (Classic HD) WW Ice-Pick Lodge (remake)
Engine	Unity (remake)
Platform(s)	Microsoft Windows, OS X, Linux, PlayStation 4, Xbox One
Release date(s)	Microsoft Windows CIS 9 June 2005 EU 18 August 2006 WW 29 October 2015 (Classic HD) Remake: Microsoft Windows, OS X, Linux, PlayStation 4, Xbox One WW Fall 2016
Genre(s)	Adventure, survival, role-playing
Mode(s)	Single-player

Pathologic (Russian: Мор. Утопия, tr. Mor. Utopiya; IPA: [mˈor. ʊtˈopʲɪjə]; En. Pestilence. Utopia) is a 2005 psychological horror adventure survival role-playing video game developed by Russian game studio Ice-Pick Lodge. It was published in Russia, and other CIS countries, by Buka Entertainment. The game was published in Europe on 18 August 2006 by G2 Games. An updated version of the original game titled Pathologic Classic HD, featuring a new English translation, updated graphics, and enhanced compatibility, was developed by General Arcade for Microsoft Windows, and was released on 29 October 2015, being published by Gambitious Digital Entertainment and Devolver Digital. A full remake of the game in Unity is also currently being developed for Microsoft Windows, OS X, Linux, PlayStation 4 and Xbox One, and is scheduled for release in fall 2016, being developed and to be published again by Ice-Pick Lodge.

Gameplay

The game is about three characters who are mostly known by their nicknames: two men, Bachelor (Бакалавр) and Haruspex (Гаруспик), and a girl nicknamed Devotress (re-translated to "Changeling" in the "Classic HD" version) (Самозванка). Each of them tries to uncover the source of a strange lethal sickness known as the "sand plague" that has befallen a small town. Although players can play as each of them, there is only one storyline, which is seen from different points of view depending upon the chosen character. The ability to uncover some secrets depend on which character is being played and the characters also interact with the other two unchosen characters and discuss their progress over the course of the game.

The game takes place in a perpetual world over a time frame of 12 in-game days. Throughout each day, the player receives quests from non-player characters (NPCs), however, the game continues regardless of whether they are completed or not. At exactly midnight of each day, the incomplete quests are erased from the player's notebook. Quests are divided into main missions, (one per day) which decide if a major character will die, and side quests, which earn money and items. Completing main quests is essential to discovering the secrets of the town, as characters can fall ill from the plague early in the game who would otherwise reveal information later in the game.

While trying to discover the secrets of the town, the player's other goal is simply to survive to the end of the 12 days by balancing various resources within the game's fluctuating economy, which represents the harsh "supply and demand" nature of a shut-off disease ridden town.

On the edge of town, there is a great building named Polyhedron (Многогранник), a geometrically impossible structure used as a fortress by children. On the opposite side lies an ominous cattle-slaughtering Abattoir, with the Apiary (re-translated to Termitary in the "Classic HD" version), an insane asylum, next to it. All districts and major buildings of the town are named after body parts and biology.

Reception

Pathologic was critically well received, winning five major Russian awards. However, its reception in English-speaking countries has been varied, being both praised for its remarkable atmosphere and concept while equally panned for its poor translation, outdated graphics and slow gameplay.

Since release, the game has become a cult classic, with Rock, Paper, Shotgun notably writing a 3-part article on the game describing it as "the single best and most important game you've never played."

Remake

Ice-Pick Lodge expressed interest in creating a crowd-funded remake of the game, and on 4 September 2014, a Kickstarter campaign for the remake was launched. The campaign was successful, gathering $333,127 of its funding goal of $250,000. The remake version will feature new quests and content, improved visuals from the Unity engine, more balanced gameplay, smarter AI for the NPCs, realistic behavior patterns for the Sand Plague disease, and improved English localization.

A remaster of the original titled Pathologic Classic HD was released on 29 October 2015. It's a separate release from the remake. It features improved graphics, cloud saves and a new translation.

References

External links

• Official website
• Pathologic at MobyGames
• "Butchering Pathologic", Rock, Paper, Shotgun article

UpToDate Contents

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English Journal

• Two-photon microscopy of the mouse cochlea in situ for cellular diagnosis.

• Yang X, Pu Y, Hsieh CL, Ong CA, Psaltis D, Stankovic KM.SourceÉcole Polytechnique Fédérale de Lausanne, School of Engineering, Optics Laboratory, BM 4.107, Station 17, CH-1015 Lausanne, Switzerland.
• Journal of biomedical optics.J Biomed Opt.2013 Mar 1;18(3):31104. doi: 10.1117/1.JBO.18.3.031104.
• ABSTRACT. Sensorineural hearing loss is the most common type of hearing loss worldwide, yet the underlying cause is typically unknown because the inner ear cannot be biopsied today without destroying hearing, and intracochlear cells have not been imaged with resolution sufficient to establish diagno
• PMID 23165736

• MAPT H1 haplotype is associated with enhanced α-synuclein deposition in dementia with Lewy bodies.

• Colom-Cadena M, Gelpi E, Martí MJ, Charif S, Dols-Icardo O, Blesa R, Clarimón J, Lleó A.SourceNeurology Department, Institut d'Investigacions Biomediques Sant Pau, Hospital de Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.
• Neurobiology of aging.Neurobiol Aging.2013 Mar;34(3):936-42. doi: 10.1016/j.neurobiolaging.2012.06.015. Epub 2012 Jul 21.
• The microtubule-associated protein tau (MAPT) H1 haplotype has been identified as a genetic risk factor for synucleinopathies. However, whether it modulates tau or α-synuclein pathology remains unknown. Our aim was to investigate the relationship between MAPT haplotypes and pathologic aggregates of
• PMID 22819391

Japanese Journal

• Needlescopic video-assisted wedge resection combined with the subcostal trans-diaphragmatic approach for undetermined peripheral pulmonary nodules

• Oda Makoto,Matsumoto Isao,Takizawa Masaya,Waseda Ryuichi,Suzuki Mitsutaka,Ishiyama Yasuhiro,Abe Takatoshi,Ishikawa Norihiko,Watanabe Go
• Surgical Endoscopy 27(10), 3671-3677, 2013-10-00
• … The pathologic diagnosis of the nodules was malignant for 28 patients and benign for 8 patients. …
• NAID 120005254088

• Erythromycin treatment suppresses myocardial injury in autoimmune myocarditis in rats via suppression of superoxide production.

• Hirano Emi,Shimada Kana,Komiyama Taeka,Fujita Masatoshi,Kishimoto Chiharu
• International journal of cardiology 167(5), 2228-2233, 2013-09-01
• … [Results]EM treatment reduced the severity of myocarditis compared with the untreated group in a dose-dependent manner by comparing the heart weight/body weight ratio, pathologic scores, and myocardial macrophage, CD4+, and CD8+ infiltrations. …
• NAID 120005324907

• Mitochondrial DNA with a Large-Scale Deletion Causes Two Distinct Mitochondrial Disease Phenotypes in Mice

• Katada Shun,Mito Takayuki,Ogasawara Emi,Hayashi Jun-Ichi,Nakada Kazuto,林 純一,中田 和人
• G3: Genes, Genomes, Genetics 3(9), 1545-1552, 2013-09-00
• … To determine whether ∆mtDNA has the pathologic potential to induce multiple mitochondrial disease phenotypes, we used trans-mitochondrial mice with a heteroplasmic state of wild-type mtDNA and ∆mtDNA (mito-mice∆). …
• NAID 120005342668

Related Links

• Pathologic | Define Pathologic at Dictionary.com

As a result of this pathologic picture the authors are of the opinion that they may have been dealing with a mild infection. Scurvy Past and Present Alfred Fabian Hess An agent which causes the dispersal of a tumor or of a ...

• Pathologic

What Pathologic Feels Like It’s a game that always makes you feel in a pinch—but being in a pinch also feels worth it. Whichever of the three playable characters you choose, your goal will always be to determine the origins of Sand ...

Related Pictures

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★リンクテーブル★

リンク元	「morbid」「病的」「病理」「pathologically」「病態的」
拡張検索	「psychopathological」「pathological process」「histopathological finding」「psychopathologic」

「morbid」

　　[★]

• adj.

• (精神など)病的な。病的に陰気な。(医)疾患性の。気味の悪い、ぞっとするような。(まれ)病気を起こすような

関

morbidity、morbidly、pathologic、pathologically

　 　

「病的」

　　[★]

英

pathologic、morbid、pathologically、morbidly

関

病態、病態的、病理、罹患、病理学的、病理的

「病理」

　　[★]

英

pathology、pathologic

関

症状、病態、病態学、病態的、病的、病理学、病理的

「pathologically」

　　[★]

• adv.

• 病理学的に、病態的に、病的に

関

morbid、morbidly、pathologic、pathological

　

「病態的」

　　[★]

英

pathologic、pathologically

関

病態、病的、病理、病理学的、病理的

「psychopathological」

　　[★]

• 精神病理学的な、精神病理学の

関

psychopathology

「pathological process」

　　[★]

• 病理過程、病的過程

関

pathologic process

「histopathological finding」

　　[★]

• 病理組織所見、病理組織学的所見

「psychopathologic」

　　[★]

• 精神病理の

関

psychopathology