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1. 選択的IgE欠損症 selective ige deficiency
2. 選択的IgA欠損症：管理および予後 selective iga deficiency management and prognosis
3. 稀な（劣性遺伝性）凝固異常 rare recessively inherited coagulation disorders
4. アンチトロンビン（ATIII）欠乏症 antithrombin atiii deficiency
5. ビタミンB12および葉酸欠乏症の病因および臨床症状 etiology and clinical manifestations of vitamin b12 and folate deficiency

Deletion of the Wolfram syndrome-related gene Wfs1 results in increased sensitivity to ethanol in female mice.

Raud S1, Reimets R2, Loomets M2, Sütt S2, Altpere A2, Visnapuu T2, Innos J2, Luuk H2, Plaas M2, Volke V2, Vasar E2.
Neuropharmacology.Neuropharmacology.2015 Aug;95:59-67. doi: 10.1016/j.neuropharm.2015.02.019. Epub 2015 Feb 25.
Wolfram syndrome, induced by mutation in WFS1 gene, increases risk of developing mood disorders in humans. In mice, Wfs1 deficiency cause higher anxiety-like behaviour and increased response to anxiolytic-like effect of diazepam, a GABAA receptor agonist. As GABAergic system is also target for ethan
PMID 25725334

AMPK deficiency in cardiac muscle results in dilated cardiomyopathy in the absence of changes in energy metabolism.

Sung MM1, Zordoky BN1, Bujak AL2, Lally JS2, Fung D1, Young ME3, Horman S4, Miller EJ5, Light PE6, Kemp BE7, Steinberg GR2, Dyck JR8.
Cardiovascular research.Cardiovasc Res.2015 Jul 15;107(2):235-45. doi: 10.1093/cvr/cvv166. Epub 2015 May 28.
AIMS: AMP-activated protein kinase (AMPK) is thought to be a central player in regulating myocardial metabolism and its activation has been shown to inhibit cardiac hypertrophy. Recently, mice with muscle-specific deletion of AMPK β1/β2 subunits (AMPKβ1β2-deficient mice, β1β2M-KO) have been ge
PMID 26023060

Coenzyme Q10 and Fish Oil Synergistically Alleviate Aluminum Chloride-induced Suppression of Testicular Steroidogenesis and Antioxidant Defense.

Mohammad NS, Arafa MH, Atteia HH.
Free radical research.Free Radic Res.2015 Jul 3:1-63. [Epub ahead of print]
Aluminum (Al) is an environmental xenobiotic that stimulates free radical generation and hence reproductive toxicity. Coenzyme Q10 (CoQ10) shows effectiveness in counteracting free radicals-induced tissue damage. Omega-3 polyunsaturated fatty acids present in fish oil (FO) exert beneficial effects o
PMID 26140385