UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 心血管疾患の明確な危険因子の概要overview of established risk factors for cardiovascular disease [show details]
… Elevated levels of white blood cells, erythrocyte sedimentation rates, IL-18, tumor necrosis factor alpha,… 54 percent of all patients and 70 percent of those with a lipid abnormality in one reported series had a familial lipid disorder .…
2. 腎細胞癌の疫学、病理、および病因epidemiology pathology and pathogenesis of renal cell carcinoma [show details]
…sarcomatoid RCC tumors are enriched in CD274 (programmed cell death ligand 1 [PD-L1] gene) amplifications , have higher PD-L1 protein expression on tumor cells , greater tumor infiltration by CD8+ T cells ,… of sheets of cells that are darker than clear cell carcinoma. They lack the abundant lipid and glycogen that is characteristic of most RCCs, and originate from the intercalated cells of the collecting…
3. 肺の炎症性筋線維芽細胞性腫瘍（形質細胞肉芽腫）inflammatory myofibroblastic tumor plasma cell granuloma of the lung [show details]
… histogenesis of these uncommon tumors or tumor-like masses Much of the confusion has been caused by the varying degrees of inflammatory cell infiltration noted on pathologic… frequently contain finely vacuolated cytoplasmic lipid droplets. Plasma cells may contain cytoplasmic Russell bodies (globular…
4. 虚血性脳卒中の二次予防の概要overview of secondary prevention of ischemic stroke [show details]
… with a higher risk for monozygotic twins and those with genetic disorders such as sickle cell disease or cerebral autosomal dominant arteriopathy with… efficacy for reducing the risk of recurrent ischemic stroke. The available evidence suggests that lipid lowering by other means (eg, fibrates, bile acid sequestrants, niacin, diet) has no significant impact …
5. 非アルコール性脂肪性肝疾患の病因pathogenesis of nonalcoholic fatty liver disease [show details]
…family of lipid molecules, are involved in inflammation and cell toxicity via interaction with tumor necrosis factor alpha. Inhibition of ceramide synthesis has been shown to diminish steatosis, cell injury …