verrucous carcinoma

WordNet

1. any malignant tumor derived from epithelial tissue; one of the four major types of cancer

PrepTutorEJDIC

1. がん,がん腫

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2012/04/10 08:50:54」(JST)

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Verrucous carcinoma
Classification and external resources
An exophytic and hyperkeratotic mass that discharged malodorous debris through several sinus tracts
ICD-O:	M8051/3
eMedicine	derm/452
MeSH	D018289

Verrucous carcinoma (also known as Carcinoma cuniculatum, and Ackerman tumor) is an uncommon variant of squamous cell carcinoma. This form of cancer is often seen in those who chew tobacco or use snuff orally, so much so that it is sometimes referred to as "Snuff dipper's cancer."

Most patients with verrucous carcinoma have a good prognosis. Local recurrence is not uncommon, but metastasis to distant parts of the body is rare. Patients with oral verrucous carcinoma may be at greater risk of a second oral squamous cell carcinoma, for which the prognosis is worse.

Classification

Verrucous carcinoma may be divided into the following four types:

• Type I, also known as Oral florid papillomatosis
• Type II, also known as Anogential type verrucous carcinoma
• Type III, also known as Epithelioma cuniculatum
• Type IV

Definition

It’s a diffuse, papillary, non metastasizing, well differentiated, malignant neoplasm of epidermis or oral epithelium. It is also known as an Ackerman tumor.

Etiology

This form of cancer is often seen in those who chew tobacco or use snuff orally, so much so that it is sometimes referred to as "Snuff dipper's cancer."

Clinical features

• age- usually over 60 yrs
• sex- males are more prone
• site- gingiva, buccal mucosa, alveolar mucosa, hard palate, floor of the mouth, larynx, oesophagus, penis, vagina, scrotum.
• clinical presentation-
  • It’s a slow growing, diffuse, exophytic lesion usually covered by Leukoplakik patches.
  • Invasive lesions quickly invade bones
  • It is rapidly become fixed with underlying periosteum and cause gradual destruction of jaw bone.
  • Enlarged regional lymph nodes
  • Lesion shows painful multiple rugae like folds and deep clefts between them.

Treatment

Surgical excision or laser therapy

See also

• Giant condyloma acuminatum
• Squamous cell carcinoma
• List of cutaneous conditions

References

External links

• eMedicine.com article
• Maxillofacial Center for Education & Research article
• Cancer Management Handbook: Head and Neck Tumors

• verrucous carcinoma pics

UpToDate Contents

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English Journal

• Subset of patients with verrucous carcinoma of the oral cavity who benefit from treatment with methotrexate.

• Karagozoglu KH, Buter J, Leemans CR, Rietveld DH, van den Vijfeijken S, van der Waal I.SourceDepartment of Oral and Maxillofacial Surgery/Oral Pathology, VU University Medical Center/Academic Centre for Dentistry Amsterdam, The Netherlands.
• The British journal of oral & maxillofacial surgery.Br J Oral Maxillofac Surg.2011 Oct 13. [Epub ahead of print]
• Oral verrucous carcinoma (OVC) is a low-grade variant of squamous cell carcinoma (SCC) with a distinctive morphology and specific pattern of behaviour that is often diagnosed in elderly patients. Resection is the treatment of choice, with radiotherapy as a reasonable alternative. In this retrospecti
• PMID 22000636

Japanese Journal

• 症例 頸部リンパ節転移および遠隔転移したと思われる口角のVerrucous Carcinomaの1例

• 原嶋 秀明,本多 芳英
• 皮膚科の臨床 53(5), 781-784, 2011-05
• NAID 40018827758

Related Links

• Verrucous carcinoma - Wikipedia, the free encyclopedia

Verrucous carcinoma is an uncommon variant of squamous cell carcinoma. This form of cancer is often seen in those who chew tobacco or use snuff orally, so much so that it is sometimes referred to as "Snuff dipper's cancer." Most patients ...

• Dermatologic Manifestations of Verrucous Carcinoma

24 Jan 2012 ... Dermatologic Manifestations of Verrucous Carcinoma. Verrucous carcinoma (VC) refers to a clinicopathologic concept implying a locally aggressive, clinically exophytic, low-grade, slow-growing, well-differentiated squamous ...

Related Pictures

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★リンクテーブル★

リンク元	「腫瘍」「疣状癌」「いぼ状癌」「疣状がん」「いぼ状がん」
拡張検索	「verrucous carcinoma of penis」

「腫瘍」

　　[★]

英

tumor

同

新生物 neoplasm new growth NG

関

分類(EPT.65)

悪性度

• 良性腫瘍 benign tumor
• 悪性腫瘍 malignant tumor

細胞と間質の割合

• 髄様癌
• 硬性癌

発生学的由来

• 上皮性腫瘍

• 外胚葉性、中胚葉性、内胚葉性

• 非上皮性腫瘍

• 間質由来(中胚葉性)

組織学的分類

上皮性腫瘍

良性腫瘍

• 乳頭腫
• 腺腫
• 嚢胞腺腫

悪性腫瘍

• 癌腫

• 腺癌
• 扁平上皮癌
• 移行上皮癌
• 未分化癌

非上皮性腫瘍

良性腫瘍

• 線維腫

• 硬性線維腫
• 軟性線維腫:線維脂肪腫との区別が困難

• 脂肪腫

• 骨髄脂肪腫

• 平滑筋腫
• 横紋筋腫
• 血管腫
• リンパ管腫
• 神経鞘腫
• 神経線維腫
• 色素性母斑
• 中皮腫

悪性腫瘍

• 肉腫

• 線維肉腫：悪性線維性組織球腫
• 脂肪肉腫

• 脂肪腫用脂肪肉腫
• 粘液性脂肪肉腫
• 多形性脂肪肉腫
• 横紋筋肉腫

• 血管肉腫
• リンパ肉腫
• 神経原性肉腫
• 滑膜肉腫
• 悪性黒色腫
• 悪性中皮腫

臓器別分類

外陰部(女性)

• 乳房外パジェット病 extramammary Paget disease
• 悪性黒色腫
• verrucous carcinoma of vagina

子宮

• 子宮頚癌
• 子宮内膜癌

卵巣

• 卵巣腫瘍

• 表層上皮性・間質性腫瘍 Surface epithelial-stromal tumors
• 性索間質性腫瘍 Sex cord/stromal tumors
• 胚細胞腫瘍 Germ cell tumors

「疣状癌」

　　[★]

英

verrucous carcinoma

同

疣状有棘細胞癌 verrucous squamous cell carcinoma

関

疣状がん、いぼ状癌、いぼ状がん

「いぼ状癌」

　　[★]

英

verrucous carcinoma

関

疣状癌、疣状がん、いぼ状がん

「疣状がん」

　　[★]

英

verrucous carcinoma

関

疣状癌、いぼ状癌、いぼ状がん

「いぼ状がん」

　　[★]

英

verrucous carcinoma

関

疣状癌、疣状がん、いぼ状癌

「verrucous carcinoma of penis」

　　[★] ブシュケ・レーヴェンシュタイン腫瘍。陰茎疣状癌