WordNet
- develop into a distinctive entity; "our plans began to take shape" (同)take form, take shape, spring
- assume a form or shape; "the water formed little beads"
- the visual appearance of something or someone; "the delicate cast of his features" (同)shape, cast
- a mold for setting concrete; "they built elaborate forms for pouring the foundation"
- a particular mode in which something is manifested; "his resentment took the form of extreme hostility"
- a perceptual structure; "the composition presents problems for students of musical form"; "a visual pattern must include not only objects but the spaces between them" (同)shape, pattern
- (biology) a group of organisms within a species that differ in trivial ways from similar groups; "a new strain of microorganisms" (同)variant, strain, var.
- the phonological or orthographic sound or appearance of a word that can be used to describe or identify something; "the inflected forms of a word can be represented by a stem and a list of inflections to be attached" (同)word form, signifier, descriptor
- a printed document with spaces in which to write; "he filled out his tax form"
- an ability to perform well; "he was at the top of his form"; "the team was off form last night"
- an arrangement of the elements in a composition or discourse; "the essay was in the form of a dialogue"; "he first sketches the plot in outline form"
- to compose or represent:"This wall forms the background of the stage setting"; "The branches made a roof"; "This makes a fine introduction" (同)constitute, make
- create (as an entity); "social groups form everywhere"; "They formed a company" (同)organize, organise
- having or given a form or shape
PrepTutorEJDIC
- 〈C〉〈U〉(色・材質に対して)『形』,形状,姿 / 〈C〉『人体』,体つき / 〈C〉〈U〉『外観』,格好,人影 / 〈C〉〈U〉(ものの現れる)『形態』,形式 / 〈C〉(生物などの)『種類』,品種 / 〈U〉(芸術作品の)表現形式 / 〈U〉(特にスポーツで)(競技者の)フォーム / 〈U〉(心身の)調子,元気 / 〈C〉(印刷された)書き込み用紙,ひな形 / 〈U〉《話》(ある集団などの)やり方,仕方,方式 / 〈C〉〈U〉しきたり,伝統的な儀式 / 〈C〉(英国の学校・米国のある学校で)学年,学級 / 〈U〉〈C〉(意味に対する)形態,形;語形 / 〈C〉(通例寄りかかりのない)長い木のいす / 〈素材〉‘に'形を与える,(…に)…‘を'形作る《+『名』+『into』+『名』》 / (素材から)…‘を'形作る《+『名』+『out of』+『名』》 / …‘を'組織する,構成する / 〈考えなど〉‘を'まとめる,思い付く;〈計画など〉‘を'立てる / 〈習慣など〉‘を'身に付ける;〈交際など〉‘を'結ぶ / 〈文章など〉‘を'組み立てる;〈複数形など〉‘を'作る / (ある順序に)配列する,整列させる / 〈物が〉形を成す / 生じる,現れる / (…に)なる《+『into』+『名』》
- 《時間・距離》『…の間』 / 《利益・貢献》『…のために』 / 《適応・用途》『…向きの(に);』…用の(に);…のための(に) / 《目的・意向》『…のために,』に / 《敬意・記念》『…のために;』…を記念して / 《獲得・追求》『…を得るために』,を求めて / 《行く先・方向》『…あてに;』…[方面]行きの,に向けて / 《交換・報償など》『…に対して』;…と引き換えに;…のお返しに / 《原因・理由》『…のために』,なので / 《代理・代表》『…の代わりに;』…を代表して / 《形容詞の後に用いて》『…にとって,』には / 《比較級の後に用いて》『…の結果として,』…のために / 《対比》『…としては,』のわりには / 《関連》『…について,』の点では / 《資格・属性》『…として』 / 《賛成・支持》…『に賛成して』,を支持して / 《傾向・好み》…『に対する』,には / 《模倣》《おもに米》《英文》…の名を取って(after) / 《割合》…に対して / 《『for』+『名』〈人〉+『to』 doの形で,〈人〉が不定詞to doの意味上の主語を表して》…が(…することは,…するために) / […というのは]…だから
UpToDate Contents
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English Journal
- Targeting of pegylated liposomal mitomycin-C prodrug to the folate receptor of cancer cells: Intracellular activation and enhanced cytotoxicity.
- Patil Y1, Amitay Y2, Ohana P2, Shmeeda H3, Gabizon A4.
- Journal of controlled release : official journal of the Controlled Release Society.J Control Release.2016 Mar 10;225:87-95. doi: 10.1016/j.jconrel.2016.01.039. Epub 2016 Jan 22.
- Mitomycin C (MMC) is a powerful anti-bacterial, anti-fungal and anti-tumor antibiotic, often active against multidrug resistant cells. Despite a broad spectrum of antitumor activity, MMC clinical use is relatively limited due to its fast clearance and dose-limiting toxicity. To exploit the potential
- PMID 26809007
- Correlation of in Situ Oxazolidine Formation with Highly Synergistic Cytotoxicity and DNA Cross-Linking in Cancer Cells from Combinations of Doxorubicin and Formaldehyde.
- Barthel BL1, Mooz EL1, Wiener LE2, Koch GG2, Koch TH1.
- Journal of medicinal chemistry.J Med Chem.2016 Mar 10;59(5):2205-21. doi: 10.1021/acs.jmedchem.5b01956. Epub 2016 Feb 26.
- Anthracyclines are a class of antitumor compounds that are successful and widely used but suffer from cardiotoxicity and acquired tumor resistance. Formaldehyde interacts with anthracyclines to enhance antitumor efficacy, bypass resistance mechanisms, improve the therapeutic profile, and change the
- PMID 26881291
- Polymeric Prodrug Grafted Hollow Mesoporous Silica Nanoparticles Encapsulating Near-Infrared Absorbing Dye for Potent Combined Photothermal-Chemotherapy.
- Zhang Y1, Ang CY1, Li M1, Tan SY1, Qu Q1, Zhao Y1,2.
- ACS applied materials & interfaces.ACS Appl Mater Interfaces.2016 Mar 9. [Epub ahead of print]
- In this study, polymeric prodrug coated hollow mesoporous silica nanoparticles (HMSNs) with encapsulated near-infrared (NIR) absorbing dye were prepared and explored for combined photothermal-chemotherapy. A copolymer integrated with tert-butoxycarbonyl protected hydrazide groups and oligoethylene g
- PMID 26937591
Japanese Journal
- (4)変異型単純ヘルペスウイルス(HSV)を用いた卵巣癌に対する治療戦略 : 新規がんウイルス療法の開発と構築を目指して(<特集>第61回学術講演会シンポジウム3「卵巣癌の新たな治療戦略-基礎から,そして臨床から-」)
- 那波 明宏
- 日本産科婦人科學會雜誌 61(11), 2054-2070, 2009-11-01
- … The virus disappeared completely by 3 days postinfection and failed to induce any significant histopathological changes on the normal skin, in contrast, KH7, which was isolated from clinical samples, caused severe zoster form on it by 7 days postinfection with the same titer of the virus. …
- NAID 110007467576
- Preparation and Prodrug Studies of Quercetin Pentabenzensulfonate
- Peng You,Deng Zeyuan,Wang Chunfeng
- 藥學雜誌 128(12), 1845-1849, 2008-12-01
- … Pentabenzensulfonate (QPBS), a potential prodrug for quercetin, was designed and synthesized in high yield. … It possesses better physical properties such as solubility, lipid/water partition coefficient, LogP, and hydrolysis kinetics than its original form. … These results indicate that QPBS can be considered as a potential prodrug for quercetin. …
- NAID 110007005968
Related Links
- prodrug /pro·drug/ (-drug) a compound that, on administration, must undergo chemical conversion by metabolic processes before becoming an active pharmacological agent; a precursor of a drug. pro·drug (pr dr g) n. A class of drugs ...
- A prodrug form of 5-fluorouracil selected from the group consisting of optionally substituted 1-alkoxycarbonyl, 3-acyl, 1-acyloxyalkyl and 3-acyloxyalkyl derivatives of 5-fluorouracil having a) a partition coefficient between octanol and ...
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- Progression rates are variable and an acute aggressive form with death in 6 months can occur.(疾患の進展速度は症例により様々で、6ヶ月で死亡する急性増悪も起こりうる)(CASES.244)
- 関
- appearance、breed、configure、cultivar、figure、formation、mode、morphology、orchestrate、pattern、race、shape、topology、type、typed