分娩後甲状腺機能障害
WordNet
- (medicine) any disturbance in the functioning of an organ or body part or a disturbance in the functioning of a social group; "erectile dysfunction"; "sexual relationship dysfunction" (同)disfunction
- suggestive of a thyroid disorder; "thyroid personality"
- of or relating to the thyroid gland; "thyroid deficiency"; "thyroidal uptake" (同)thyroidal
PrepTutorEJDIC
- 機能障害,機能不全
- 甲状腺 / 甲状腺の
- 出産後の,分娩(ぶんべん)後の
UpToDate Contents
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English Journal
- Differentiation of Postpartum Graves' Thyrotoxicosis from Postpartum Destructive Thyrotoxicosis by Anti-TSH Receptor Antibodies and Thyroid Blood Flow.
- Ide A, Amino N, Yoshioka W, Kang S, Kudo T, Nishihara E, Ito M, Nakamura H, Miyauchi A.Author information Kuma Hospital, Kobe, Japan ; ide@kuma-h.or.jp.AbstractBackground: Postpartum thyroid dysfunction occurs in approximately 5-10% of women in the general population within one year of delivery. Differentiation of postpartum Graves' thyrotoxicosis (PPGr) from postpartum destructive thyrotoxicosis (PPDT) is essential because of the difference in treatment measures between the two. However, it is sometimes difficult because radioactive iodine uptake is contraindicated when patients are lactating. We examined the usefulness of postpartum onset time and measurement of anti-TSH receptor antibodies and thyroid blood flow. Methods: Forty-two patients who newly developed thyrotoxicosis after delivery were examined: 18 had Graves' disease and 24 had destructive thyrotoxicosis. Serum free T4 (FT4), free T3 (FT3), and TSH were measured by chemiluminescent immunoassay. Anti-TSH receptor antibodies (TRAb), anti-thyroglobulin antibodies (TgAb), and anti-TPO antibodies (TPOAb) were measured by the Elecsys electrochemiluminescence immunoassay. Thyroid volume and blood flow (TBF) were measured quantitatively by color flow Doppler ultrasonography. Results: Onset of thyrotoxicosis was distributed from 2 months to 12 months postpartum. Twelve (85.7%) of 14 patients who developed thyrotoxicosis at 3 months or earlier after delivery had PPDT. On the other hand, all 11 patients who developed thyrotoxicosis at 6.5 months or later had PPGr. All patients with PPGr had positive TRAb (14.9 ± 14.9 IU/l, mean ± SD) and all patients with PPDT had negative TRAb (0.1 ± 0.3 IU/l, p<0.0001). Fifteen (83.3%) of 18 PPGr patients had high TBF of more than 4.0% (8.9 ± 4.4, mean ± SD) and all PPDT patients had low TBF of less than 4.0% (1.6 ± 1.0, p<0.0001). FT3/FT4 ratio was higher in PPGr (64.0 ± 23.9) than in PPDT (38.9 ± 13.1, p<0.0002), but absolute values overlapped between the two. Conclusion: Postpartum early onset of thyrotoxicosis was associated mainly with PPDT and a late onset was suggestive of PPGr. Positive TRAb and high TBF of more than 4.0% are indicators of postpartum onset of Graves' disease.
- Thyroid : official journal of the American Thyroid Association.Thyroid.2014 Jan 8. [Epub ahead of print]
- Background: Postpartum thyroid dysfunction occurs in approximately 5-10% of women in the general population within one year of delivery. Differentiation of postpartum Graves' thyrotoxicosis (PPGr) from postpartum destructive thyrotoxicosis (PPDT) is essential because of the difference in treatment m
- PMID 24400892
- [The impact of thyroid function in women at the reproductive age: infertility, pregnancy and the postpartum period].
- Speer G.Author information Betegápoló Irgalmasrendi Kórház Budapest Frankel Leó út 54. 1023.Abstractin
English, HungarianA szerző a terhesség alatt és post partum észlelt pajzsmirigy-megbetegedések kezelésére és diagnózisára vonatkozó lehetőségeket ismerteti, több szakmai társaság által készült és 2012-ben publikált ajánláson keresztül. Bemutatja ezen ajánlás alapjait és meg nem oldott kérdéseit is, különösen a TSH-szűréssel kapcsolatos álláspontokban. Terhességben a hyperthyreosis okai a kezelendő Basedow-kór, az ettől gyakran nehezen megkülönböztethető terhességi, átmeneti thyreotoxicosis, amely nem kezelendő. A post partum thyreoiditis jóval gyakrabban fordul elő pajzsmirigy-peroxidáz-ellenes antitestpozitív nőkben, akik esetén ezért a TSH-szintet a terhesség 6. és 12. hete között, illetve a szülés utáni 3. és 6. hónapban ellenőrizni kell. A hypothyreosis autoimmun eredetű, és nem kizárólag a manifeszt formája, hanem a szubklinikai megjelenése is kezelendő. Minden pajzsmirigybetegség szerepet játszik a meddőség patomechanizmusában is. Orv. Hetil., 2013, 154(51), 2017–2023.
- Orvosi hetilap.Orv Hetil.2013 Dec 1;154(51):2017-23. doi: 10.1556/OH.2013.29774.
- in
English, HungarianA szerző a terhesség alatt és post partum észlelt pajzsmirigy-megbetegedések kezelésére és diagnózisára vonatkozó lehetőségeket ismerteti, több szakmai társaság által készült és 2012-ben publikált ajánláson keresztül. Bemutatja ezen ajánlás alapjait
- Increased thyroid autoimmunity among women with multiple sclerosis in the postpartum setting.
- Jalkanen A, Saraste M, Gfeller A, Surcel H, Airas L.Author information Department of Neurology, Turku University Hospital, Finland.AbstractBACKGROUND: Multiple sclerosis (MS) patients are predisposed to thyroid abnormalities, but the risk for pregnancy-related thyroid pathology among MS patients has not been evaluated.
- Multiple sclerosis (Houndmills, Basingstoke, England).Mult Scler.2013 Nov;19(13):1734-42. doi: 10.1177/1352458513485148. Epub 2013 Apr 29.
- BACKGROUND: Multiple sclerosis (MS) patients are predisposed to thyroid abnormalities, but the risk for pregnancy-related thyroid pathology among MS patients has not been evaluated.OBJECTIVES: The objectives of this research are to prospectively evaluate the prevalence of thyroid autoimmunity among
- PMID 23629943
Japanese Journal
- 出産後甲状腺機能異常症の概念と対策 (特集 甲状腺疾患 : 診断・治療の最新動向) -- (妊娠と甲状腺疾患)
- Low concordance between positive antibodies to thyroperoxidase and thyroid ultrasound autoimmune pattern in pregnant women
- JISKRA Jan,BARTAKOVA Jana,HOLINKA Stepan,LIMANOVA Zdenka,SPRINGER Drahomira,FAIT Tomas,ANTOSOVA Marie,TELICKA Zdenek,POTLUKOVA Eliska
- Endocrine journal 58(10), 849-859, 2011-10-01
- … The diagnostic and prognostic role of thyroid ultrasound (TUS) in pregnant women positive for antibodies to thyroperoxidase (TPOAb) is unclear. … The aim of our study was to compare the relation of ultrasound thyroid texture to the thyroid laboratory tests in pregnant women and controls. …
- NAID 10029863052
- 産後の甲状腺機能異常症 (特集 甲状腺疾患と妊娠)
Related Links
- 1. Clin Lab. 2011;57(9-10):731-9. Postpartum thyroid dysfunction: a state of immunological dysregulation. Swelam Eel S, Bakr HG, Mansour MA. Clinical Pathology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
- History of Non-Hodgkins Lymphoma. Thyroid dysfunction. Why hair is graying? My husband is 47 yo with history of Non- Hodgkins Lymphoma . He has been in remission for 12 years but a few years ago they started treating him with ...
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