関節破壊

WordNet

come into the company of; "She joined him for a drink"
cause to become joined or linked; "join these two parts so that they fit together" (同)bring together
make contact or come together; "The two roads join here" (同)conjoin
become part of; become a member of a group or organization; "He joined the Communist Party as a young man" (同)fall_in, get together
united or combined; "a joint session of Congress"; "joint owners"
marijuana leaves rolled into a cigarette for smoking (同)marijuana cigarette, reefer, stick, spliff
a disreputable place of entertainment
junction by which parts or objects are joined together
(anatomy) the point of connection between two bones or elements of a skeleton (especially if it allows motion) (同)articulation, articulatio
provide with a joint; "the carpenter jointed two pieces of wood" (同)articulate
affecting or involving two or more; "joint income-tax return"; "joint ownership"
fasten with a joint
fit as if by joints; "The boards fit neatly"
involving both houses of a legislature; "a joint session of Congress"
separate (meat) at the joint
the termination of something by causing so much damage to it that it cannot be repaired or no longer exists (同)devastation
an event (or the result of an event) that completely destroys something (同)demolition, wipeout
the act of bringing two things into contact (especially for communication); "the joining of hands around the table"; "there was a connection via the internet" (同)connection, connexion
having joints or jointed segments;

PrepTutorEJDIC

〈二つ以上のもの〉‘を'『つなぐ』,結合する《+『名』+『together』(『up』)》;(…に)…‘を'つなぐ《+『名』+『to』(『onto』)+『名』》 / (線などで)〈二つ以上のもの〉‘の'間を結ぶ(つなぐ)《+『名』+『by』(『with』)+『名』》 / (友情・結婚などで)〈人〉‘を'結びつける《+『名』+『in』+『名』》 / 〈川・道などが〉…‘と'いっしょになる,合流する / 〈会など〉‘に'『加入する』 / (…で)〈人〉‘の'『仲間に入る』,‘と'いっしょになる《+『名』〈人〉+『in』(『for』)+『名』,+『名』〈人〉+『in』do『ing』》 / (…に)『加わる』《+『in』+『名』〈事〉/+『in』『with』+『名』〈人〉》 / (人と…を)『ともにする』《+『with』+『名』〈人〉+『in』+『名』(doing)》 / 〈川・道などが〉『いっしょになる』,合流する / 接合箇所(点,面,線);継ぎ目
『関節』 / 『継ぎ目』,接合箇所,合わせ目 / 継ぎ目と継ぎ目の間の部分,節 / (二つの部分を継いだり支えたりするのに用いる)継ぎ手,ジョイント / (枝や葉の)つけ根,節 / (骨付きの)肉の大切り身 / 《俗》安酒場,とばく宿,アヘン窟(くつ) / 『共同の』,共有の;連帯の,連合の / 両院合同の;二院制議会の両院の / …‘を'継ぎ合わせる;…‘を'継ぎ目(関節)でつなぐ / …‘を'継ぎ目で分ける;〈鳥・肉など〉‘を'関節で切り分ける
『破壊』[行為] / 破壊された状態,破滅,絶滅 / 破壊手段,破壊をもたらすもの
継ぎ目のある;関節のある

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1. 重度の関節リウマチに対する全関節置換術 total joint replacement for severe rheumatoid arthritis
2. 上肢の関節保護プログラム joint protection program for the upper limb
3. 関節の疼痛または腫脹を有する小児の評価 evaluation of the child with joint pain or swelling
4. 母指痛患者の評価 evaluation of the patient with thumb pain
5. 関節血腫 hemarthrosis

English Journal

miR-370 and miR-373 regulate the pathogenesis of osteoarthritis by modulating one-carbon metabolism via SHMT-2 and MECP-2, respectively.

Song J1, Kim D1, Chun CH2, Jin EJ1.
Aging cell.Aging Cell.2015 Oct;14(5):826-37. doi: 10.1111/acel.12363. Epub 2015 Jun 24.
The aim of this study was to determine the mechanism underlying the association between one-carbon metabolism and DNA methylation during chronic degenerative joint disorder, osteoarthritis (OA). Articular chondrocytes were isolated from human OA cartilage and normal cartilage biopsied, and the degre
PMID 26103880

Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) mediates periarticular bone loss, but not joint destruction, in murine antigen-induced arthritis.

Shimizu T1, Takahata M2, Kameda Y1, Endo T1, Hamano H1, Hiratsuka S1, Ota M1, Iwasaki N1.
Bone.Bone.2015 Oct;79:65-70. doi: 10.1016/j.bone.2015.05.029. Epub 2015 May 28.
Osteoclastogenesis requires immunoreceptor tyrosine-based activation motif signaling. Multiple immunoreceptors associated with immunoreceptor tyrosine-based activation motif adaptor proteins, including DNAX-activating protein 12kDa (DAP12) and Fc receptor common γ (FcRγ), have been identified in o
PMID 26027508

Intraarticular Matrix Metalloproteinases and Aggrecan Degradation Are Elevated After Articular Fracture.

Haller JM1, Swearingen CA, Partridge D, McFadden M, Thirunavukkarasu K, Higgins TF.
Clinical orthopaedics and related research.Clin Orthop Relat Res.2015 Oct;473(10):3280-8. doi: 10.1007/s11999-015-4441-4. Epub 2015 Jul 11.
BACKGROUND: Posttraumatic osteoarthritis (OA) is a variant of OA that can develop after articular injury. Although the mechanism(s) of posttraumatic OA are uncertain, the presence and impact of postinjury proteolytic enzymes on articular cartilage remain unknown. To our knowledge, there are no studi
PMID 26162411

Japanese Journal

Pedicle versus free frozen autograft for reconstruction in malignant bone and soft tissue tumors of the lower extremities

Shimozaki Shingo,Yamamoto Norio,Shirai Toshiharu,Nishida Hideji,Hayashi Katsuhiro,Tanzawa Yoshikazu,Kimura Hiroaki,Takeuchi Akihiko,Igarashi Kentaro,Inatani Hiroyuki,Kato Takashi,Tsuchiya Hiroyuki
Journal of Orthopaedic Science 19(1), 156-163, 2014-01
… Postoperative complications occurred in 8 cases: infection in 3 cases, fracture in 3 cases, and joint destruction in 2 cases. …
NAID 120005349170

症例報告脛骨内側顆に関節破壊を伴う化膿性膝関節炎に対し,部分セメントスペーサーで感染を鎮静化させた後,人工膝関節に置換した1例

瓜牛拓也,樋口富士男,吉川英一郎 [他]
臨床整形外科 48(8), 813-817, 2013-08
NAID 40019762755

The long-term immunosuppressive effects of disulfide-linked HLA-G dimer in mice with collagen-induced arthritis

Kuroki Kimiko,Hirose Kaoru,Okabe Yuki,Fukunaga Yuko,Takahashi Ami,Shiroishi Mitsunori,Kajikawa Mizuho,Tabata Shigekazu,Nakamura Seiko,Takai Toshiyuki,Koyanagi Satoru,Ohdo Shigehiro,Maenaka Katsumi
HUMAN IMMUNOLOGY 74(4), 433-438, 2013-04
… HLA-G, a natural immunosuppressant present in the human placenta during pregnancy, prevents fetal destruction by the maternal immune system. … Mice were treated with the HLA-G monomer or dimer intracutaneously at the left foot joint, once or for 5 days, and the clinical severity was evaluated daily in a double-blind study. …
NAID 120005297913