- 関
- clinical research、clinical study、clinical test、clinical trial、examine、exploration、explore、inquire、inquiry、investigate、investigation、investigative、laboratory research、probing、research、scan、study、surveillance、survey、trial、work
WordNet
- provoke or excite; "The rock musician worked the crowd of young girls into a frenzy"
- (physics) a manifestation of energy; the transfer of energy from one physical system to another expressed as the product of a force and the distance through which it moves a body in the direction of that force; "work equals force times distance"
- arrive at a certain condition through repeated motion; "The stitches of the hem worked loose after she wore the skirt many times"
- a product produced or accomplished through the effort or activity or agency of a person or thing; "it is not regarded as one of his more memorable works"; "the symphony was hailed as an ingenious work"; "he was indebted to the pioneering work of John Dewey"; "the work of an active imagination"; "erosion is the work of wind or water over time" (同)piece of work
- activity directed toward making or doing something; "she checked several points needing further work"
- have an effect or outcome; often the one desired or expected; "The voting process doesnt work as well as people thought"; "How does your idea work in practice?"; "This method doesnt work"; "The breaks of my new car act quickly"; "The medicine works only if you take it with a lot of water" (同)act
- be employed; "Is your husband working again?"; "My wife never worked"; "Do you want to work after the age of 60?"; "She never did any work because she inherited a lot of money"; "She works as a waitress to put herself through college" (同)do work
- cause to work; "he is working his servants hard" (同)put to work
- shape, form, or improve a material; "work stone into tools"; "process iron"; "work the metal" (同)work on, process
- behave in a certain way when handled; "This dough does not work easily"; "The soft metal works well"
- cause to operate or function; "This pilot works the controls"; "Can you work an electric drill?"
- exert oneself by doing mental or physical work for a purpose or out of necessity; "I will work hard to improve my grades"; "she worked hard for better living conditions for the poor"
- gratify and charm, usually in order to influence; "the political candidate worked the crowds"
- move in an agitated manner; "His fingers worked with tension"
- move into or onto; "work the raisins into the dough"; "the student worked a few jokes into his presentation"; "work the body onto the flatbed truck"
- operate in a certain place, area, or specialty; "She works the night clubs"; "The salesman works the Midwest"; "This artist works mostly in acrylics"
- operate in or through; "Work the phones"
- proceed towards a goal or along a path or through an activity; "work your way through every problem or task"; "She was working on her second martini when the guests arrived"; "Start from the bottom and work towards the top"
- be a student; follow a course of study; be enrolled at an institute of learning
- a room used for reading and writing and studying; "he knocked lightly on the closed door of the study"
- applying the mind to learning and understanding a subject (especially by reading); "mastering a second language requires a lot of work"; "no schools offer graduate study in interior design" (同)work
- a composition intended to develop one aspect of the performers technique; "a study in spiccato bowing"
- a state of deep mental absorption; "she is in a deep study"
- someone who memorizes quickly and easily (as the lines for a part in a play); "he is a quick study"
- give careful consideration to; "consider the possibility of moving" (同)consider
- learn by reading books; "He is studying geology in his room"; "I have an exam next week; I must hit the books now" (同)hit the books
- think intently and at length, as for spiritual purposes; "He is meditating in his study" (同)meditate, contemplate
- read metrically; "scan verses"
- an image produced by scanning; "he analyzed the brain scan"; "you could see the tumor in the CAT scan" (同)CAT scan
- the act of scanning; systematic examination of a prescribed region; "he made a thorough scan of the beach with his binoculars"
- examine hastily; "She scanned the newspaper headlines while waiting for the taxi" (同)skim, rake, glance over, run_down
- conform to a metrical pattern
- examine minutely or intensely; "the surgeon scanned the X-ray"
- make a wide, sweeping search of; "The beams scanned the night sky"
- move a light beam over; in electronics, to reproduce an image
- (law) the determination of a persons innocence or guilt by due process of law; "he had a fair trial and the jury found him guilty"; "most of these complaints are settled before they go to trial"
- trying something to find out about it; "a sample for ten days free trial"; "a trial of progesterone failed to relieve the pain" (同)trial_run, test, tryout
- an annoying or frustrating or catastrophic event; "his mother-in-laws visits were a great trial for him"; "life is full of tribulations"; "a visitation of the plague" (同)tribulation, visitation
- (sports) a preliminary competition to determine qualifications; "the trials for the semifinals began yesterday"
- the work of inquiring into something thoroughly and systematically (同)investigating
PrepTutorEJDIC
- 〈U〉(一般的な)『仕事,』労働;努力,勉強 / 〈U〉(実際にやっている具体的な)『仕事』,作業,勉強 / 〈U〉《定冠詞なしで》『仕事の口,』職[業],(工場・会社などの)勤め先 / 〈U〉制作,細工;《比喩(ひゆ)的に》しわざ / 〈C〉《しばしば複数形で》(文学・芸術の)『作品,』著作,(ある人の)作品 / 〈U〉《集合的に》(材料・道具などを含めて)作っているもの(今しているもの)全部 / 《複数形で》(機械の)動く部分,仕掛け / 《複数形で》《単数・複数扱い》《しばしば複合語を作って》『工場』 / 《複数形で》(宗教・道徳的な)行為,行い / 〈U〉(物理学で)仕事量 / 『働く』,仕事をする;(…に)取り組む,(…を)勉強する《+『at』(『on』)+『名』》 / (…に)『勤める』,勤務する《+『at』(『on, for』)+『名』》 / 《しばしば副詞[句]を伴って》〈機械・道具などが〉『ぐあいよく動く,』作動する,〈計画などが〉うまくいく,〈薬などが〉効く / 《副詞[句]を伴って》(ある方向に)少しずつ進む / 〈顔などが〉ぴくぴく動く,〈波などが〉揺れる / 《通例副詞を伴って》細工される,こねられる / 発酵する / 〈機械・道具など〉‘を'『動かす』,運転する / 〈人・牛馬など〉‘を'『働かせる』 / 〈工場・鉱山・農場など〉‘を'操業(経営)する,〈土地〉‘を'耕作する / 〈ある地域〉‘を'活動場所にする,受け持つ / 〈結果・効果など〉‘を'もたらす,生じさせる / (手で)…‘を'細工する,加工する;…‘に'手を加えて(…を)作る《+名+into+名》 / 《副詞[句]を伴って》(苦労して)…‘を'進む,(努力して)…‘を'得る / 〈人・物〉‘を'動かして(…に)する《+名+to(into)+名》 / …‘を'刺しゅうする,縫い付ける
- 〈U〉(一般に)『勉強』,学習すること / 〈C〉(…の)勉強,研究《+of+名》 / 〈C〉〈U〉(…の)『綿密な調査』,検討《+of+名》 / 〈C〉研究対象(問題,事項);学科 / 〈C〉『書斎』,勉強部屋 / 〈C〉(美術・文学などの)習作,試作,スケッチ,(音楽の)練習曲,エチュード / …‘を'『勉強する』,学ぶ,研究する / …‘を'『よく注意して見る』,しげしげと見る / …‘を'『調査する』,検討する / …‘を'考慮する,配慮する / 〈せりふなど〉‘を'覚えようとする / 『勉強する』,学ぶ,研究する
- …‘を'じっと見る,詳しく調べる;〈広い区域〉‘を'端から端までよく見る / …‘に'さっと目を通す,‘を'ざっと読む / 〈詩〉‘の'韻律を調べる,‘を'詩脚に分ける / (テレビ・レーダーで)〈映像〉‘を'走査する / 詩の韻律を調べる;〈詩行が〉韻律の法則に合う,音脚が合う / (テレビ・レーダーで)走査をする / じっと見ること,吟味
- 〈U〉〈C〉『裁判』,公判,審理 / 〈U〉〈C〉(…の)『試験』,ためし《+of+名》 / 〈C〉企て,試み;努力 / 〈C〉(忍耐・徳・信仰などをためす)試練,苦難 / 〈C〉困りもの,迷惑な(やっかいな)人(もの)
- (…の)『調査』,取り調べ,研究《+『of』(『into』)+『名』》
UpToDate Contents
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English Journal
- TLR9-Targeted SiRNA Delivery In Vivo.
- Hossain DM1, Moreira D1, Zhang Q1, Nechaev S1,2, Swiderski P3, Kortylewski M4.
- Methods in molecular biology (Clifton, N.J.).Methods Mol Biol.2016;1364:183-96. doi: 10.1007/978-1-4939-3112-5_15.
- The SiRNA strategy is a potent and versatile method for modulating expression of any gene in various species for investigational or therapeutic purposes. Clinical translation of SiRNA-based approaches proved challenging, mainly due to the difficulty of targeted SiRNA delivery into cells of interest
- PMID 26472451
- New and Investigational Agents for Irritable Bowel Syndrome.
- Wadhwa A1, Camilleri M2, Grover M3.
- Current gastroenterology reports.Curr Gastroenterol Rep.2015 Dec;17(12):46. doi: 10.1007/s11894-015-0473-x.
- Irritable bowel syndrome (IBS) affects about 15 % of the US population and results in significant morbidity and health care costs. There remains a significant unmet need for effective treatments particularly for the pain component of IBS and other functional gastrointestinal disorders (FGIDs). Prog
- PMID 26446557
- Catheter securement systems: comparison of two investigational devices to a sutureless securement device, a securement dressing, and sutures in a pig model.
- Rutledge LF1, DeCabooter DP, Walters SA, Bernatchez SF.
- Intensive care medicine experimental.Intensive Care Med Exp.2015 Dec;3(1):60. doi: 10.1186/s40635-015-0060-3. Epub 2015 Aug 27.
- BACKGROUND: Catheter securement is critical for the success of infusion therapy and to prevent complications. Our purpose was to compare the strength of catheter securement achieved with two investigational adhesive securement devices to two securement products and also to sutures using an in vivo a
- PMID 26307415
- Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain.
- Roy SL1, Atkins JT2, Gennuso R2, Kofos D2, Sriram RR3, Dorlo TP4,5, Hayes T6, Qvarnstrom Y7, Kucerova Z3, Guglielmo BJ8, Visvesvara GS3.
- Parasitology research.Parasitol Res.2015 Dec;114(12):4431-9. doi: 10.1007/s00436-015-4684-8. Epub 2015 Sep 2.
- Balamuthia mandrillaris, a free-living ameba, causes rare but frequently fatal granulomatous amebic encephalitis (GAE). Few patients have survived after receiving experimental drug combinations, with or without brain lesion excisions. Some GAE survivors have been treated with a multi-drug regimen in
- PMID 26329128
Japanese Journal
- 発達保障の源流 発達心理学研究の方法について : 大津における活動をもとに
- 研究者主導未承認薬開発試験の実施および規制上の諸問題 : アカデミアの立場から (第3回 がん新薬開発合同シンポジウム がん新薬開発の新しい潮流 : 世界をリードする医療イノベーション実現に向けて)
- 医療機器をめぐる現状と展望(53)人への初使用を含む初期フィージビリティー試験のIDEについての米国の新指針
- Symposium Review 医薬品における味覚センサの応用 : 開発から市販後まで
Related Links
- The Journal of Investigational Allergology and Clinical Immunology (J Investig Allergol Clin Immunol) provides an attractive and very active forum for basic and clinical research in allergology and clinical immunology. The journal ...
- 患者の為の治験・臨床試験ポータルサイト。患者サイドに立って治験及び臨床試験に関する情報を提供。 ... IND IND(Investigational New Drug) 米国における 臨床試験申請で使われる用語で 臨床試験を行うとしている新医薬品(候補)
- 1: of or relating to investigation <investigational activities> 2: relating to or being a drug or medical procedure that is not approved for general use but is ... Seen and Heard What made you want to look up investigational? Please tell us ...
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★リンクテーブル★
[★]
- 英
- clinical trial、clinical study、clinical research、clinical test、trial、investigation、investigational
- 関
- 研究、試み、試験、試行、調査、臨床試験、検討、臨床研究、臨床治験、臨床的研究
定義
- 参考1
- 治験(clinical research)とは医薬品もしくは医療機器の製造販売の承認申請をするために行われる臨床試験のことである。
治験に参加する健常者・患者に対するインフォームドコンセント
- 参考1
- 治験を行う者は、治験への参加者に対して、治験に先立ち、実施される試験の目的や内容について説明する義務がある。
- また、参加者が患者であるならば、その治療法などについてのメリットとデメリット、他の存在する治療法などを詳しく説明し、予想される最悪の帰結に関してまでの合意がなければならない。
- そして、十分な理解の出来た参加者本人の自由意思によってのみ治験への参加は決断されねばならない。
- また、いつでも参加者は自由に治験からは離脱でき、治験からの離脱に対して、今後の治療や経済的制裁などの不利益を被ることが一切ないことを保証しなければならない(間接的な強制も許されない)。
参考
- http://ja.wikipedia.org/wiki/%E6%B2%BB%E9%A8%93
- 2. 医療機器の臨床試験の実施の基準に関する省令
- http://law.e-gov.go.jp/htmldata/H17/H17F19001000036.html
[★]
- 研究、勉学、学習
- (~の)研究、学問。[-ies](従事している)研究、学業(in,on,of,into)
- 慎重な調査、詳細な検討
- 研究対象/研究題目。研究論文、論考。[-ies]学科
- (~に関して)研究に値するもの、見もの、(~の)具体例(in)
- 書斎、勉強部屋、研究室
- 関
- examine、exploration、explore、inquire、inquiry、investigate、investigation、investigational、investigative、laboratory research、probing、research、scan、surveillance、survey、work
[★]
- 英
- research、study、investigation、survey、scan、surveillance、exploration、probing、inquiry、investigate、survey、study、examine、scan、explore、investigational、investigative、inquire
- 関
- 監視、研究、検査、サーベイランス、試験、質問、照会、調べる、審査、走査、探究、探索、治験、レスポンデント、検討、調査監視、問い合わせ、スキャン、データ収集、リサーチ、データソース
[★]
- 探検/踏査/探査する。(医)(傷・器官などを)診査/探査する。
- (問題などを)探究する、調査する
- (未体験のものを)試してみる
- 関
- examine、exploration、exploratory、inquire、inquiry、investigate、investigation、investigational、investigative、probe、probing、pursue、pursuit、research、scan、search、seek、study、surveillance、survey
[★]
- 関
- assessment、check、checkup、evaluate、exam、examination、exploration、explore、inquire、inquiry、inspection、interrogate、investigate、investigation、investigational、investigative、look、probing、research、scan、study、surveillance、survey、test、testing、trial
[★]
- 関
- IND、investigational agent、investigational new drug
[★]
- 関
- IND、investigational drug、investigational new drug
[★]
治験薬 IND
- 関
- investigational agent、investigational drug
[★]
- 調査(of, into)、取り調べ、研究。研究論文、調査報告。
- 検査