特発性好酸球増多症候群
WordNet
- a pattern of symptoms indicative of some disease
- a complex of concurrent things; "every word has a syndrome of meanings"
- (of diseases) arising from an unknown cause; "idiopathic epilepsy"
PrepTutorEJDIC
- (疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態
- 特発性疾患の(病気の原因があいまいな,また不明な場合)
UpToDate Contents
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English Journal
- Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome.
- Smith SM1, Kiracofe EA, Clark LN, Gru AA.
- The American Journal of dermatopathology.Am J Dermatopathol.2015 Dec;37(12):910-4. doi: 10.1097/DAD.0000000000000279.
- IMPORTANCE: Wells syndrome (WS) (eosinophilic cellulitis) is an uncommon eosinophilic dermatitis that has been rarely described in association with, but distinct from, hypereosinophilic syndrome (HES).OBSERVATIONS: We report a case of an eosinophilic dermatosis with flame figures in association with
- PMID 25839890
- Pediatric idiopathic hypereosinophilic syndrome with Gianotti-Crosti syndrome: a novel presentation.
- Molvi MA1, Sharma YK1, Dash K1, Patwekar M1, Kohli S1, Panicker NK2.
- International journal of dermatology.Int J Dermatol.2015 Dec;54(12):1416-9. doi: 10.1111/ijd.12301. Epub 2014 Apr 16.
- PMID 24738625
Japanese Journal
- 症例報告 発熱・肝腫大を呈した小児特発性好酸球増多症候群
- 専門医のためのアレルギー学講座 9.好酸球増多を主徴とする疾患(1)Idiopathic Hypereosinophilic Syndrome (idiopathic HES)
Related Links
- However, due to advances in the diagnostic techniques, secondary causes of eosinophilia can be identified in a proportion of cases that would have otherwise been classified as idiopathic hypereosinophilic syndrome. The ...
- Background Idiopathic hypereosinophilic syndrome (HES) is a rare and potentially lethal disorder characterized by persistently elevated eosinophil counts without any underlying causes. Two variants, the myeloproliferative and ...
★リンクテーブル★
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- 英
- imatinib
- 化
- imatinib mesylate
- 商
- グリベック
- 関
- nib
- 分子標的薬剤
分類
-
概念
特徴
構造
作用機序
- ABLや、活性複合体であるv-ABL, BCR-ABL, [EVT6]-ABLを阻害する (GOO.1367)
- (そのほかに)PDGFRとKITに対しても競合阻害作用を持つ (GOO.1367)
- KITはgastrointestinal stromal tumor(GIST)と関連
- ETV6-PDGFRはchronic myelomonocytic leukemia(CMML)と関連
- FIP1L1-PDGFRAはhypereosinophilic syndrome(HES)と関連
薬理作用
動態
適応
グリベック錠100mg
- 1. 慢性骨髄性白血病
- 2. KIT陽性消化管間質腫瘍
- 3. フィラデルフィア染色体陽性急性リンパ性白血病
注意
禁忌
副作用
相互作用
類似薬
添付文書
- http://www.info.pmda.go.jp/go/pack/4291011F1028_1_11/4291011F1028_1_11?view=body
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- 英
- idiopathic hypereosinophilic syndrome
- 関
- 好酸球増多症候群、特発性好酸球増加症候群、好酸球性白血病、レフラー心内膜炎
[show details]
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レフラー心内膜炎、Loeffler心内膜炎
- 関
- eosinophilic leukemia、hypereosinophilic syndrome、idiopathic hypereosinophilic syndrome
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- 英
- idiopathic hypereosinophilic syndrome
- 関
- 特発性好酸球増多症候群
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- 関
- agnogenic、cryptogenic、idiopathy
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好酸球増多症候群 HES
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