Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/12/21 06:10:31」(JST)

Dilazep is a vasodilator that acts as an adenosine reuptake inhibitor.^[1]

References

^ Hiroshi Deguchi, Hiroyuki Takeya, Hideo Wada, Esteban C. Gabazza, Nobuyuki Hayashi, Hajime Urano, and Koji Suzuki (September 15, 1997). "Dilazep, an Antiplatelet Agent, Inhibits Tissue Factor Expression in Endothelial Cells and Monocytes". Blood 90: 2345–2356.

This drug article relating to the cardiovascular system is a stub. You can help Wikipedia by expanding it.

A 10-year-old girl with IgA nephropathy who 5 years later developed the characteristic features of Henoch-Schonlein purpura nephritis.

Chishiki M, Kawasaki Y, Kaneko M, Ushijima Y, Ohara S, Abe Y, Suyama K, Hashimoto K, Hosoya M.SourceDepartment of Pediatrics, Fukushima Medical University, Fukushima, Japan.
Fukushima journal of medical science.Fukushima J Med Sci.2010 Dec;56(2):157-61.
We report a patient who developed Henoch-Schonlein purpura (HSP) 5 years after she presented with immunoglobulin A nephropathy (IgAN). A 10-year-old Japanese female was identified with proteinuria and hematuria by a school urinary screening. The first renal biopsy showed mesangial proliferative glo
PMID 21502718

Estimation of endogenous adenosine activity at adenosine receptors in guinea-pig ileum using a new pharmacological method.

Nilsson KF, Grishina VA, Glaumann C, Gustafsson LE.SourceDepartment of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
Acta physiologica (Oxford, England).Acta Physiol (Oxf).2010 Jun;199(2):231-41. Epub 2010 Jan 30.
AIM: Adenosine modulates neurotransmission and in the intestine adenosine is continuously released both from nerves and from smooth muscle. The main effect is modulation of contractile activity by inhibition of neurotransmitter release and by direct smooth muscle relaxation. Estimation of adenosine
PMID 20121712

Successful therapy with tonsillectomy plus pulse therapy for the relapse of pediatric IgA nephropathy treated with multi-drugs combination therapy

Successful therapy with tonsillectomy plus pulse therapy for the relapse of pediatric IgA nephropathy treated with multi-drugs combination therapy

リンク元	「抗狭心症薬」「ジラゼプ」
拡張検索	「dilazep dihydrochloride」

Dilazep
Systematic (IUPAC) name
	3-(4-{3-[(3,4,5-trimethoxyphenyl)carbonyloxy]propyl}-1,4-diazepan-1-yl)propyl 3,4,5-trimethoxybenzoate
Clinical data
AHFS/Drugs.com	International Drug Names
Identifiers
ATC code	C01DX10
PubChem	CID: 3074
IUPHAR/BPS	4717
ChemSpider	2965
UNII	F8KLC2BD5Z
KEGG	D07843
ChEMBL	CHEMBL126075
Chemical data
Formula	C31H44N2O10
Molecular mass	604.69 g/mol
	SMILES O=C(OCCCN2CCCN(CCCOC(=O)c1cc(OC)c(OC)c(OC)c1)CC2)c3cc(OC)c(OC)c(OC)c3 ;
	InChI InChI=1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3 ; Key:QVZCXCJXTMIDME-UHFFFAOYSA-N ;
(verify)