WordNet

limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
limit the range or extent of; "Contact between the young was inhibited by strict social customs"
relying on or requiring a person or thing for support, supply, or what is needed; "dependent children"; "dependent on moisture"
addicted to a drug (同)dependant, drug-addicted, hooked, strung-out
contingent on something else (同)dependant, qualified
(of a clause) unable to stand alone syntactically as a complete sentence; "a subordinate (or dependent) clause functions as a noun or adjective or adverb within a sentence" (同)subordinate
a substance that retards or stops an activity
an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
the basic unit of money in Papua New Guinea

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1. マントル細胞リンパ腫の病理学 pathobiology of mantle cell lymphoma
2. 多発性内分泌腫瘍1型：定義および遺伝学 multiple endocrine neoplasia type 1 definition and genetics
3. 黒色腫（メラノーマ）に対する遺伝的感受性 inherited susceptibility to melanoma
4. 前立腺癌の分子生物学 molecular biology of prostate cancer
5. 胃癌の病理および分子学的病因 pathology and molecular pathogenesis of gastric cancer

sMEK1 enhances gemcitabine anti-cancer activity through inhibition of phosphorylation of Akt/mTOR.

Byun HJ, Kim BR, Yoo R, Park SY, Rho SB.SourceResearch Institute, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, Republic of Korea.
Apoptosis : an international journal on programmed cell death.Apoptosis.2012 Oct;17(10):1095-103.
Recently, we reported that sMEK1 is down-regulated in cancer cells and tissues, and that it enhances the pro-proliferative effect as a novel pro-apoptotic protein. However, the biological mechanism of the sMEK1 tumor suppressor in the cellular signal pathway has not been well understood. In our curr
PMID 22903553

Gambogenic acid induces G1 arrest via GSK3β-dependent cyclin D1 degradation and triggers autophagy in lung cancer cells.

Yu XJ, Han QB, Wen ZS, Ma L, Gao J, Zhou GB.SourceDivision of Molecular Carcinogenesis and Targeted Therapy for Cancer, State Key Laboratory of Biomembrane and Membrane Biotechnology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.
Cancer letters.Cancer Lett.2012 Sep 28;322(2):185-94. Epub 2012 Mar 9.
Cyclin D1, an oncogenic G1 cyclin which can be induced by environmental carcinogens and whose over-expression may cause dysplasia and carcinoma, has been shown to be a target for cancer chemoprevention and therapy. In this study, we investigated the effects and underlying mechanisms of action of a p
PMID 22410463

Inverse correlation between Skp2 and p27(Kip1) in normal endometrium and endometrial carcinoma

Miyamoto Tsutomu,Horiuchi Akiko,Kashima Hiroyasu,Suzuki Akihisa,Yamada Tomoko,Kurai Miyuki,Konishi Ikuo,Shiozawa Tanri
GYNECOLOGICAL ENDOCRINOLOGY 26(3), 220-229, 2010-03
… GYNECOLOGICAL ENDOCRINOLOGY is available online at: http://dx.doi.org/10.3109/09513590903215482Cyclin-dependent-kinase (cdk) inhibitor, p27<SUKip1</SU (p27), has been shown to participate in progestin-induced growth suppression of normal endometrial glands. …
NAID 120002598960

Apoptosis of Human Lung Cancer Cells by Curcumin Mediated through Up-Regulation of “Growth Arrest and DNA Damage Inducible Genes 45 and 153”

Saha Achinto,Kuzuhara Takashi,Echigo Noriko,Fujii Atsuko,Suganuma Masami,Fujiki Hirota
Biological & Pharmaceutical Bulletin 33(8), 1291-1299, 2010
… Moreover, curcumin induced the expression of cyclin dependent kinase inhibitor genes p21 and p27, while it inhibited the expression of numerous genes, including Bcl-2, cyclin D1, CDK2, CDK4 and CDK6. …
NAID 130000300350

リンク元	「サイクリン依存性キナーゼ阻害因子p27」
関連記事	「inhibit」「inhibitor」「dependent」「kinase」「dependent kinase」