creatine kinase MB

クレアチンキナーゼMB

関

MB form creatine kinase

WordNet

1. an amino acid that does not occur in proteins but is found in the muscle tissue of vertebrates both in the free form and as phosphocreatine; supplies energy for muscle contraction (同)creatin
2. the 13th letter of the Roman alphabet (同)m
3. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
4. the imperial dynasty of China from 1368 to 1644 (同)Ming dynasty
5. the basic unit of money in Papua New Guinea

PrepTutorEJDIC

1. Mach number / mark[s] / Monsieur
2. (中国の)明,明朝(1368‐1644)

UpToDate Contents

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• 1. 心筋障害のバイオマーカーとしてのトロポニンおよびクレアチンキナーゼ troponins and creatine kinase as biomarkers of cardiac injury
• 2. 急性心筋梗塞の診断基準 criteria for the diagnosis of acute myocardial infarction
• 3. 神経筋疾患の評価における筋酵素 muscle enzymes in the evaluation of neuromuscular diseases
• 4. 腎不全患者における血清心臓バイオマーカー serum cardiac biomarkers in patients with renal failure
• 5. トロポニンおよびクレアチンキナーゼ以外の心筋障害を示唆するバイオマーカー biomarkers suggesting cardiac injury other than troponins and creatine kinase

English Journal

• The age factor for mitoxantrone's cardiotoxicity: Multiple doses render the adult mouse heart more susceptible to injury.

• Dores-Sousa JL1, Duarte JA2, Seabra V3, Bastos Mde L4, Carvalho F4, Costa VM5.
• Toxicology.Toxicology.2015 Mar 2;329:106-19. doi: 10.1016/j.tox.2015.01.006. Epub 2015 Jan 9.
• Age is a known susceptibility factor for the cardiotoxicity of several anticancer drugs, including mitoxantrone (MTX). The impact of anticancer drugs in young patients is underestimated, thus we aimed to evaluate the cardiotoxicity of MTX in juvenile and adult animals. Juvenile (3 week-old) and adul
• PMID 25582955

• Remote ischemic conditioning and cardioprotection: a systematic review and meta-analysis of randomized clinical trials.

• Le Page S1, Bejan-Angoulvant T, Angoulvant D, Prunier F.
• Basic research in cardiology.Basic Res Cardiol.2015 Mar;110(2):467. doi: 10.1007/s00395-015-0467-8. Epub 2015 Feb 5.
• Remote ischemic conditioning (RIC) represents an innovative cardioprotective method that has been investigated in numerous clinical studies providing miscellaneous results. This systematic review and meta-analysis sought to assess RIC-induced effects on myocardial injury biomarkers and clinical outc
• PMID 25653117

• In vitro cardioprotective effect of wusen erlian granules through the inhibition of coxsackievirus b3 replication.

• Cao Y1, Hao L, Han CH, Zhang PY.
• Cell biochemistry and biophysics.Cell Biochem Biophys.2015 Mar;71(2):1135-9. doi: 10.1007/s12013-014-0320-y.
• Wusen Erlian Granules are a traditional Chinese medicine and we sought to determine the antiviral activity of Wusen Erlian Granules against Coxsackievirus B3 infection. First, cytotoxicity of Wusen Erlian Granules was determined in cultured cardiomyocytes isolated from day-old Wister rat pups. Later
• PMID 25388835

Japanese Journal

• Effect of Remote Ischemic Preconditioning on the Periprocedural Myocardial Injury Events during Elective Percutaneous Coronary Intervention

• Hiroshima Journal of Medical Sciences 67, 8-14, 2018-05
• NAID 120006473829

• Prognostic Factors for In-Hospital and Long-Term Survival in Patients with Acute ST-Segment Elevation Myocardial Infarction after Percutaneous Coronary Intervention

• The Tohoku Journal of Experimental Medicine 242(1), 27-35, 2017
• NAID 130006776941

• Significant Association of Serum Adiponectin and Creatine Kinase-MB Levels in ST-Segment Elevation Myocardial Infarction

• Ｊｏｕｒｎａｌ　ｏｆ　Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　ａｎｄ　Ｔｈｒｏｍｂｏｓｉｓ 24(8), 793-803, 2017
• NAID 130005876080

Related Links

• Creatine Kinase MB (CK-MB), Human Heart - Lee ...

Buy human cardiac Creatine Kinase MB (CK-MB) for diagnostic manufacturing, control, calibrator and research uses - Inquire for details. ... Lee Biosolutions produces human Creatine Kinase MB (CK-MB) isoenzyme for research, life ...

• Creatine Kinase–MB - American Journal of Clinical Pathology

The creatine kinase (CK)–MB test volume from 2007 through 2013. The numbers for 2013 are extrapolated from the first 4 months. CK-MB was not on the acute coronary syndrome (ACS) panel for portions of View this table: In a ...

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★リンクテーブル★

リンク元	「CK-MB」「MB form creatine kinase」
関連記事	「kinase」「M」「creatine kinase」

「CK-MB」

　　[★]

英

creatine kinase-MB creatine kinase MB CK-MB

同

クレアチンキナーゼ-MB

関

クレアチンキナーゼ CK CPK、クレアチンキナーゼアイソザイム

上昇する原因

LAB.608

• 急性心筋梗塞
• 進行性筋ジストロフィー
• 皮膚筋炎
• 筋損傷に伴うミオグロビン尿症
• 薬剤性筋障害：βブロッカー、クロフィブラート、グリチルリチン

急性心筋梗塞のマーカーとして

• 心筋に特異性が高い。
• 上昇し始めるのは3-4時間
• 正常化するのは3-7日

LAB.608

• 心筋梗塞発作後4-8時間で上昇開始。24時間で最大(CK-MB/CKの40%程度まで)、3日間上昇を認める。

測定誤差

• 免疫阻害によるCK-MBを測定する方法を用いた場合、抗CK-M抗体でマクロCKを阻害することができず、正誤差を生じる。CKと免疫グロブリンが結合したマクロCK(type1)、ミトコンドリア由来の高分子型のマクロCK(type2)の存在によりCK-MB/CKが大きく見積もられる。

「MB form creatine kinase」

　　[★]

クレアチンキナーゼMB

関

creatine kinase MB

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「M」

　　[★] メチオニン methionine 　 　

「creatine kinase」

　　[★] クレアチンキナーゼ CK