creatine kinase-MB

CK-MB

WordNet

1. an amino acid that does not occur in proteins but is found in the muscle tissue of vertebrates both in the free form and as phosphocreatine; supplies energy for muscle contraction (同)creatin
2. the 13th letter of the Roman alphabet (同)m
3. an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
4. the imperial dynasty of China from 1368 to 1644 (同)Ming dynasty
5. the basic unit of money in Papua New Guinea

PrepTutorEJDIC

1. Mach number / mark[s] / Monsieur
2. (中国の)明,明朝(1368‐1644)

UpToDate Contents

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• 1. Biomarkers suggesting cardiac injury other than troponins
• 2. Troponins as biomarkers of cardiac injury
• 3. 急性心筋梗塞の診断基準 criteria for the diagnosis of acute myocardial infarction
• 4. 腎不全患者における血清心臓バイオマーカー serum cardiac biomarkers in patients with renal failure
• 5. 脳卒中の心合併症 cardiac complications of stroke

English Journal

• Increased red cell distribution width predicts occlusion of the infarct-related artery in STEMI.

• Akboga MK1, Yayla C1, Yilmaz S1, Sen F1, Balci KG1, Ozcan F1, Aras D1.
• Scandinavian cardiovascular journal : SCJ.Scand Cardiovasc J.2016 Apr;50(2):114-8. doi: 10.3109/14017431.2015.1119303. Epub 2015 Dec 14.
• Objective Infarct-related artery (IRA) patency yields a better outcome in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). Red cell distribution width (RDW) emerges as a marker of adverse cardiovascular events and mortality
• PMID 26651498

• Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-regulation of inflammatory and apoptic pathways.

• Elsherbiny NM1, Salama MF2, Said E3, El-Sherbiny M4, Al-Gayyar MM5.
• Chemico-biological interactions.Chem Biol Interact.2016 Mar 5;247:39-48. doi: 10.1016/j.cbi.2016.01.014. Epub 2016 Jan 22.
• AIM: The clinical application of the chemotherapeutic agent; Doxorubicin (DOX) is limited by its toxic effects on several body organs. The current study was conducted to evaluate the cardiao-protective effects of crocin, a predominant bioactive constituent of Saffron against DOX-induced myocardial t
• PMID 26807765

• Selective inhibition of PTEN preserves ischaemic post-conditioning cardioprotection in STZ-induced Type 1 diabetic rats: role of the PI3K/Akt and JAK2/STAT3 pathways.

• Xue R1, Lei S2, Xia ZY3, Wu Y1, Meng Q1, Zhan L1, Su W1, Liu H1, Xu J1, Liu Z4, Zhou B1, Xia Z5.
• Clinical science (London, England : 1979).Clin Sci (Lond).2016 Mar 1;130(5):377-92. doi: 10.1042/CS20150496. Epub 2015 Dec 14.
• Patients with diabetes are vulnerable to MI/R (myocardial ischaemia/reperfusion) injury, but are not responsive to IPostC (ischaemic post-conditioning) which activates PI3K (phosphoinositide 3-kinase)/Akt (also known as PKB or protein kinase B) and JAK2 (Janus kinase 2)/STAT3 (signal transducer and
• PMID 26666444

Japanese Journal

• Feasibility of Extracorporeal Shock Wave Myocardial Revascularization Therapy for Post-Acute Myocardial Infarction Patients and Refractory Angina Pectoris Patients

• International Heart Journal 58(2), 185-190, 2017
• NAID 130005556779

• Feasibility of Extracorporeal Shock Wave Myocardial Revascularization Therapy for Post-Acute Myocardial Infarction Patients and Refractory Angina Pectoris Patients

• International Heart Journal, 2017
• NAID 130005464873

• Significant Association of Serum Adiponectin and Creatine Kinase-MB Levels in ST-Segment Elevation Myocardial Infarction

• Ｊｏｕｒｎａｌ　ｏｆ　Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　ａｎｄ　Ｔｈｒｏｍｂｏｓｉｓ, 2017
• NAID 130005289976

Related Links

• CK-MB: The Test | Creatine Kinase-MB

Creatine kinase-MB (CK-MB) is one form of the enzyme creatine kinase (CK), an enzyme found primarily in heart muscle cells. The CK-MB test may help diagnose a heart attack if a troponin test is not available.

• Creatine Kinase MB (Blood) - Health Encyclopedia - University ...

Creatine Kinase MB (Blood) Does this test have other names? CK-MB What is this test? This test measures the amount of an isoenzyme of creatine kinase (CK) in your blood. It is called CK-MB. Your body makes ...

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★リンクテーブル★

リンク元	「CK-MB」
関連記事	「kinase」「M」「creatine kinase」

「CK-MB」

　　[★]

英

creatine kinase-MB creatine kinase MB CK-MB

同

クレアチンキナーゼ-MB

関

クレアチンキナーゼ CK CPK、クレアチンキナーゼアイソザイム

上昇する原因

LAB.608

• 急性心筋梗塞
• 進行性筋ジストロフィー
• 皮膚筋炎
• 筋損傷に伴うミオグロビン尿症
• 薬剤性筋障害：βブロッカー、クロフィブラート、グリチルリチン

急性心筋梗塞のマーカーとして

• 心筋に特異性が高い。
• 上昇し始めるのは3-4時間
• 正常化するのは3-7日

LAB.608

• 心筋梗塞発作後4-8時間で上昇開始。24時間で最大(CK-MB/CKの40%程度まで)、3日間上昇を認める。

測定誤差

• 免疫阻害によるCK-MBを測定する方法を用いた場合、抗CK-M抗体でマクロCKを阻害することができず、正誤差を生じる。CKと免疫グロブリンが結合したマクロCK(type1)、ミトコンドリア由来の高分子型のマクロCK(type2)の存在によりCK-MB/CKが大きく見積もられる。

「kinase」

　　[★] キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase 　

「M」

　　[★] メチオニン methionine 　 　

「creatine kinase」

　　[★] クレアチンキナーゼ CK