WordNet

criticize or reprimand harshly; "The critics came down hard on the new play"
to a lower intensity; "he slowly phased down the light until the stage was completely black"
soft fine feathers (同)down feather
(American football) a complete play to advance the football; "you have four downs to gain ten yards"
fine soft dense hair (as the fine short hair of cattle or deer or the wool of sheep or the undercoat of certain dogs) (同)pile
(usually plural) a rolling treeless highland with little soil
understood perfectly; "had his algebra problems down" (同)down pat, mastered
extending or moving from a higher to a lower place; "the down staircase"; "the downward course of the stream" (同)downward
spatially or metaphorically from a higher to a lower level or position; "dont fall down"; "rode the lift up and skied down"; "prices plunged downward" (同)downwards, downward, downwardly
cause to come or go down; "The policeman downed the heavily armed suspect"; "The mugger knocked down the old lady after she refused to hand over her wallet" (同)knock down, cut_down, push down, pull down
shoot at and force to come down; "the enemy landed several of our aircraft" (同)shoot down, land
away from a more central or a more northerly place; "was sent down to work at the regional office"; "worked down on the farm"; "came down for the wedding"; "flew down to Florida"
becoming progressively lower; "the down trend in the real estate market"
being or moving lower in position or less in some value; "lay face down"; "the moon is down"; "our team is down by a run"; "down by a pawn"; "the stock market is down today"
being put out by a strikeout; "two down in the bottom of the ninth"
bring down or defeat (an opponent)
from an earlier time; "the story was passed down from father to son"
in an inactive or inoperative state; "the factory went down during the strike"; "the computer went down again"
not functioning (temporarily or permanently); "we cant work because the computer is down"
paid in cash at time of purchase; "put ten dollars down on the necklace"
shut; "the shades were down"
reach or enter a state, relation, condition, use, or position; "The water came to a boil"; "We came to understand the true meaning of life"; "Their anger came to a boil"; "I came to realize the true meaning of life"; "The shoes came untied"; "come into co
be found or available; "These shoes come in three colors; The furniture comes unassembled"
come to pass; arrive, as in due course; "The first success came three days later"; "It came as a shock"; "Dawn comes early in June"
happen as a result; "Nothing good will come of this"
develop into; "This idea will never amount to anything"; "nothing came of his grandiose plans" (同)add up, amount
be received; "News came in of the massacre in Rwanda" (同)come_in
move toward, travel toward something or somebody or approach something or somebody; "He came singing down the road"; "Come with me to the Casbah"; "come down here!"; "come out of the closet!"; "come into the room" (同)come_up
to be the product or result; "Melons come from a vine"; "Understanding comes from experience" (同)follow
cover a certain distance; "She came a long way"
exist or occur in a certain point in a series; "Next came the student from France"
experience orgasm; "she could not come because she was too upset"
extend or reach; "The water came up to my waist"; "The sleeves come to your knuckles"
have a certain priority; "My family comes first"
travel or traverse (a distance); "This car does 150 miles per hour"; "We did 6 miles on our hike every day"
the syllable naming the first (tonic) note of any major scale in solmization (同)doh, ut
proceed or get along; "How is she doing in her new job?"; "How are you making out in graduate school?"; "Hes come a long way" (同)fare, make_out, come, get along
create or design, often in a certain way; "Do my room in blue"; "I did this piece in wood to express my love for the forest" (同)make
carry on or function; "We could do with a little more help around here" (同)manage
get (something) done; "I did my job" (同)perform
English physician who first described Downs syndrome (1828-1896) (同)John L. H. Down

PrepTutorEJDIC

(高い所から)『下へ』,降りて,地面へ / (地理・地図上)南へ,下町へ;(風・流れなどが)『下(しも)手へ』;《英》(都会・大学から)地方へ,離れて / (価格・品質・温度などが)『下がって』,(数量・スピードなどが)少なく,減じて,(濃度が)薄く / (健康・風の勢いなどが)『衰えて』,気分が沈んで / (時代などが)下がって,…に至るまで / (身分・地位が)下がって / (紙面に)書き留めて,記録して / (頭金を)現金で,即金で / 最後まで,徹底的に / しっかりと,動けないように / (高い所から)…『を下がって』;…『に沿って』;…の向こうに / …の下流に / …以来 / 《名詞の前にのみ用いて》『下りの』,下への / 《名詞の前にのみ用いて》(列車・バスなどが)下りの / 《補語にのみ用いて》下に,下がって / 《補語にのみ用いて》弱まった,おさまった;落胆した,元気のない / 《補語にのみ用いて》(勝負で)負けて,すって / 《補語にのみ用いて》《おもに米話》(野球で)アウト / …‘を'打倒する,負かす,撃ち落とす / …‘を'飲み干す,飲み込む / 下り,下降 / 《複数形で》不運,逆境
(鳥の)綿毛,うぶ毛,下羽 / (植物・果実の表面の)柔らかい毛
なだらかな草原地,丘陵地帯(特にイングランド南部の小高い白亜質の草原地the Downsを言う)
〈相手が〉(話し手の方へ)『来る』,やって来る;〈話し手が〉(相手の方へ)『行く』,伺う《+『to』(『into』)+『名』》 / (ある場所に)『着く』,到着する《+『to』+『名』》 / 〈時が〉『到来する』;〈順序が〉くる / (…に)『届く』,達する《+『to』+『名』》 / 〈事が〉(…に)『起こる』,生じる,降りかかる《+『to』+『名』》,(…から)起こる《+『from』(『of』)+『名』》 / 〈物が〉現れる,できる;〈子が〉生まれる / 〈考えなどが〉(人の)心に浮かぶ《+『to』+『名』》 / 〈人が〉(…の)『出身である』,生まれである《+『from』(『of』)+『名』》 / 〈商品などが〉利用できる,手に入る / (ある状態・結果に)『なる』,至る / 《命令形で促したり警告などを表して》さあ,これこれ / 《仮定法現在で,年月・時期などを表す語[句]の前で》…が来ると / 《仮定法現在》〈障害・難関など〉が来ても / 《『come the』+『名』の形で》(…の)ふるまいをする,(…)ぶる
《疑問文・否定文を作る》 / 《否定命令文を作る》 / 《助動詞とbe動詞のどちらも含まない文に用いて付加疑問を作る》 / 《強意語として》 / 《文》《助動詞とbe動詞のどちらも含まない文に用いて倒置文を作る》 / 《あいづちを打つ場合に》 / 《先行する動詞またはそれを含む述部の代用》 / 《so,nor,neitherで始まる簡略文で》 / …‘を'『する』,行う,果たす / 《通例have done,時にbe doneの形で》…‘を'『終える』,済ませる / …‘を'作る,作り出す / …‘を'『処理する』,整える,片付ける / 〈学課〉‘を'『勉強する』,専攻する / 〈利益・害など〉‘を'与える,もたらす / 〈人〉‘に'『役立つ』,用が足りる(serve) / …の速度で進む,距離を行く / …‘を'見物する / 〈劇〉‘を'上演する;…‘の'役を演じる / …の役目(仕事)をする / 《おもに英》…‘を'だます,かつぐ / 《話》…をへとへとにさせる / 『する』;活動する / 《通例have done,時にbe doneの形で》(…を)『終える』,済ます《+『with』+『名』》 / 〈事が〉『運ぶ』;〈人が〉暮らしていく,健康である / 〈物が〉(…に)『間に合う』,十分である;〈人が〉(…に)役に立つ,向く《+『for』+『名』》 / 《複数形で》すべきこと / 〈C〉《おもに英》大宴会,大パーティー / 〈C〉《英話》詐欺,ぺてん
ド(全音階の第1音)
『来たるべき』,『次の』 / 《話》前途有望な,今売り出し中の;新進の / (…の)『到来』,接近,致着(arrival)《+『of』+『名』》

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2015/11/10 15:08:06」(JST)

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UpToDate Contents

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1. ダウン症候群：出生前スクリーニングの概要 down syndrome prenatal screening overview
2. 肥満治療における行動戦略 behavioral strategies in the treatment of obesity
3. ダウン症：臨床的特徴および診断 down syndrome clinical features and diagnosis
4. ダウン症および18トリソミーに対するスクリーニングのための、妊娠初期におけるcombined testおよびintegrated test first trimester combined test and integrated tests for screening for down syndrome and trisomy 18
5. ダウン症の母体血清スクリーニングに関する臨床検査の問題 laboratory issues related to maternal serum screening for down syndrome

English Journal

Dynamics of quiet human stance: computer simulations of a triple inverted pendulum model.

Günther M1,2, Wagner H3.
Computer methods in biomechanics and biomedical engineering.Comput Methods Biomech Biomed Engin.2016 Jun;19(8):819-34. doi: 10.1080/10255842.2015.1067306. Epub 2015 Jul 27.
For decades, the biomechanical description of quiet human stance has been dominated by the single inverted pendulum (SIP) paradigm. However, in the past few years, the SIP model family has been falsified as an explanatory approach. Double inverted pendulum models have recently proven to be inappropr
PMID 26214594

Co-immobilization of laccase and mediator through a self-initiated one-pot process for enhanced conversion of malachite green.

Sun H1, Huang W1, Yang H1, Zhang S2.
Journal of colloid and interface science.J Colloid Interface Sci.2016 Jun 1;471:20-8. doi: 10.1016/j.jcis.2016.03.009. Epub 2016 Mar 5.
Laccase is a green biocatalyst. It works with molecular oxygen and produces water as the only by-product. However, its practical application is far less than satisfactory due to the low stability/poor reusability of free laccase and the potential secondary pollution caused by dissolved mediators. To
PMID 26971065

'Government Patent Use': A Legal Approach To Reducing Drug Spending.

Kapczynski A1, Kesselheim AS2.
Health affairs (Project Hope).Health Aff (Millwood).2016 May 1;35(5):791-7. doi: 10.1377/hlthaff.2015.1120.
The high cost of patent-protected brand-name drugs can strain budgets and curb the widespread use of new medicines. An example is the case of direct-acting antiviral drugs for the treatment of hepatitis C. While prices for these drugs have come down in recent months, they still create barriers to tr
PMID 27140984