- 関
- abnormal movement、ballismus、dyskinesia、hemiballism、hemiballismus、involuntary movement
WordNet
- abnormality in performing voluntary muscle movements
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2013/02/13 13:39:59」(JST)
[Wiki en表示]
Asterixis |
Classification and external resources |
ICD-10 |
R27.8 |
ICD-9 |
781.3 |
DiseasesDB |
33950 |
MeSH |
D020820 |
Asterixis (also called the flapping tremor, or liver flap) is a tremor of the hand when the wrist is extended, sometimes said to resemble a bird flapping its wings. This motor disorder is characterized by jerking movements (as of the outstretched hands) and is associated with various encephalopathies due especially to faulty metabolism.[1] The term derives from the Greek a, "not" and stērixis, "fixed position".
Contents
- 1 Associated conditions and presentation
- 2 History
- 3 References
- 4 External links
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Associated conditions and presentation
Usually there are brief, arrhythmic interruptions of sustained voluntary muscle contraction causing brief lapses of posture, with a frequency of 3–5 Hz. It is bilateral, but may be asymmetric.
- It can be a sign of hepatic encephalopathy, damage to brain cells presumably due to the inability of the liver to metabolize ammonia to urea. The cause is thought to be predominantly related to abnormal ammonia metabolism.[2]
- Asterixis is seen most often in drowsy or stuporous patients with metabolic encephalopathies, especially in decompensated cirrhosis or acute hepatic failure.
- It is also seen in some patients with renal failure and azotemia, and in carbon dioxide toxicity.
- It can also be a feature of Wilson's disease.
History
R.D. Adams and J.M. Foley first described asterixis in 1949 in patients with severe liver failure and encephalopathy.[3]
References
- ^ "Asterixis - Definition". http://www.merriam-webster.com/medical/asterixis. Retrieved 6.1.2011.
- ^ Anne M. Larson, Diagnosis and management of acute liver failure, Curr Opin Gastroenterol., 2010, 26(3):212:221, 2010
- ^ Adams RD, Foley JM. The neurological changes in the more common types of severe liver disease. Trans American Neurology Association 1949; 74: 217-219.
External links
- -932511743 at GPnotebook
- Diagram
Symptoms and signs: nervous and musculoskeletal systems (R25–R29, 781.0, 781.2–9)
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Primarily nervous system |
Primarily CNS
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Movement disorders
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Dyskinesia: Athetosis · Tremor · Dyskinesia
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Gait abnormality
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Scissor gait · Cerebellar ataxia · Festinating gait · Marche a petit pas · Propulsive gait · Stomping gait · Spastic gait · Magnetic gait
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Lack of coordination
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Dyskinesia: Ataxia (Cerebellar ataxia/Dysmetria, Sensory ataxia)
Dysdiadochokinesia · Asterixis
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Other
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Abnormal posturing: Opisthotonus
Perceptual disorder: Hemispatial neglect
Facial weakness · Hyperreflexia · Pronator drift
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Primarily PNS
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Gait abnormality
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Steppage gait · Antalgic gait
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Primarily muscular |
Movement disorders
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Spasm (Trismus) · Fasciculation · Fibrillation · Myokymia · Cramp
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Gait abnormality
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Myopathic gait · Trendelenburg gait · Pigeon gait
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Other
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Tetany · Meningism
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Primarily skeletal |
Rachitic rosary · Clubbing
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Primarily joint |
Joint locking
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anat (n/s/m/p/4/e/b/d/c/a/f/l/g)/phys/devp
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noco (m/d/e/h/v/s)/cong/tumr, sysi/epon, injr
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proc, drug (N1A/2AB/C/3/4/7A/B/C/D)
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anat (h/r/t/c/b/l/s/a)/phys (r)/devp/prot/nttr/nttm/ntrp
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noco/auto/cong/tumr, sysi/epon, injr
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anat (h/n, u, t/d, a/p, l)/phys/devp/hist
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noco (m, s, c)/cong (d)/tumr, sysi/epon, injr
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anat (c/f/k/f, u, t/p, l)/phys/devp/cell
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noco/cong/tumr, sysi/epon, injr
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noco (arth/defr/back/soft)/cong, sysi/epon, injr
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UpToDate Contents
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English Journal
- Asterixis (flapping tremors) as an outcome of complex psychotropic drug interaction.
- Nayak R, Pandurangi A, Bhogale G, Patil N, Chate S.
- The Journal of neuropsychiatry and clinical neurosciences.J Neuropsychiatry Clin Neurosci.2012 Dec 1;24(1):E26-7.
- PMID 22450635
- Role for α6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice.
- Quik M, Park KM, Hrachova M, Mallela A, Huang LZ, McIntosh JM, Grady SR.SourceCenter for Health Sciences, SRI International, 333 Ravenswood Ave, Menlo Park, CA 94025, USA.
- Neuropharmacology.Neuropharmacology.2012 Sep;63(3):450-9. Epub 2012 May 3.
- l-Dopa-induced dyskinesias are a serious side effect that develops in most Parkinson's disease patients on dopamine replacement therapy. Few treatment options are available to manage dyskinesias; however, recent studies show that nicotine reduces these abnormal involuntary movements (AIMs) in parkin
- PMID 22579614
Japanese Journal
- Transient Myoclonic State with Asterixis: Primary Motor Cortex Hyperexcitability is Correlated with Myoclonus
- Hitomi Takefumi,Ikeda Akio,Inouchi Morito,Imamura Hisaji,Nakagawa Tomokazu,Fumuro Tomoyuki,Matsumoto Riki,Takahashi Ryosuke
- Internal Medicine 50(20), 2303-2309, 2011
- … Objective To clarify the clinical features and mechanism of the transience of myoclonus in patients with a transient myoclonic state with asterixis (TMA). …
- NAID 130001087737
- Sorafenib 投与後早期に代謝性脳症を併発し死亡した進行肝細胞癌の1例
- 本定 三季,杉本 勝俊,宮田 祐樹,佐野 隆友,市村 茂輝,村島 英学,平良 淳一,山田 幸太,古市 好宏,山田 昌彦,今井 康晴,中村 郁夫,森安 史典
- 肝臓 50(10), 595-597, 2009-10-25
- … After 14 days of oral treatment with sorafenib, we found that the patient had disorientation and asterixis, which developed to deep coma, without serious hepatic failure. …
- NAID 10026100666
Related Links
- asterixis /as·ter·ix·is/ (as″ter-ik´sis) a motor disturbance marked by intermittent lapses of an assumed posture as a result of intermittency of sustained contraction of groups of muscles; called liver flap because of its occurrence in ...
- 84 が,著者は筋放電の不完全な中断,すなわち相対 的かっ急激な筋放電の振幅の低下もasterixis を 伴うことを認めているCFig. 2)へこの筋放電の中 断は同一肢の中で必ずしも全ての被検筋間で同期 性に認められず,遠位筋または近位筋の ...
Related Pictures
★リンクテーブル★
[★]
[正答]
※国試ナビ4※ [108C011]←[国試_108]→[108C013]
[★]
- 英
- metabolic encephalopathy
- 同??
- 代謝性脳疾患 metabolic brain disease
- 関
- 肝性昏睡、肺性脳症、羽ばたき振戦
- 意識障害
特徴
代表疾患
神経内科プリント
- 神経細胞の代謝障害を起こす疾患を上げればよい
- てんかん重積発作、肝性脳症、尿毒症、CO2ナルコーシス、糖尿病性昏睡、電解質異常(Na,Ca)、内分泌障害、中毒など
- 電解質異常(Na,Ca):Kは心筋収縮に影響があり得るが、意識障害に関わることはない?低カルシウム血症はテタニー、てんかんを起こしうるが、意識障害には関わりにくい?むしろ高カルシウム血症で意識障害をきたす。
IMD.237
1) ショック:心筋梗塞、大出血など
2) 薬物、毒物
3) 無酸素ないし低酸素血症
4) DIC、全身性感染症:敗血症など
5) 肝不全、腎不全、糖尿病性高血糖、重症肝炎、内分泌疾患など
6) 低血糖、ビタミンB1欠乏: Wernicke脳症
7) 脳振盪、てんかん大発作後
8) 酸塩基平衡および電解質異常
9) 栄養障害
[★]
- 英
- asterixis
- 関
- 固定姿勢保持困難、羽ばたき振戦、肝性脳症
[show details]
[★]
- 英
- hemiballism、
- ラ
- hemiballismus
- 関
- ジスキネジア、不随意運動、固定姿勢保持困難、異常運動、ヘミバリズム、バリズム
- abnormal movement、asterixis、ballismus、dyskinesia、hemiballismus、involuntary movement
[★]
- 英
- asterixis
- 同
- アステリキシス、陰性ミオクローヌス negative myoclonus
- 関
- ジスキネジア、不随意運動、羽ばたき振戦、異常運動、片側バリズム、バリズム
- 四肢を一定の姿勢に固定することができない病態の総称。
[★]
- 英
- flapping tremor, asterixis
- 関
- 固定姿勢保持困難
羽ばたき振戦が見られる疾患