angiogenic inhibitor

• 血管新生阻害剤、血管新生抑制剤、血管新生阻害薬、血管新生抑制薬、血管新生抑制因子

関

angiogenesis inhibitor、anti-angiogenic agent、antiangiogenic agent

WordNet

1. limit, block, or decrease the action or function of; "inhibit the action of the enzyme"; "inhibit the rate of a chemical reaction"
2. control and refrain from showing; of emotions, desires, impulses, or behavior (同)bottle up, suppress
3. limit the range or extent of; "Contact between the young was inhibited by strict social customs"
4. a substance that retards or stops an activity

PrepTutorEJDIC

1. 〈感情・欲望・行動・作用など〉‘を'抑制する / (…しないように)〈人〉‘を'抑制する,妨げる《+『名』+『from』+『名』(do『ing』)》
2. 抑制する人(物) / 化学反応抑制剤

UpToDate Contents

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• 1. 後天性C1インヒビター欠損症：管理および予後 acquired c1 inhibitor deficiency management and prognosis
• 2. 後天性C1インヒビター欠損症：臨床症状、疫学、病因、および診断 acquired c1 inhibitor deficiency clinical manifestations epidemiology pathogenesis and diagnosis
• 3. C1阻害剤正常を示す遺伝性血管性浮腫（III型HAE） hereditary angioedema with normal c1 inhibitor type iii hae
• 4. 遺伝性血管浮腫：一般診療および長期予防 hereditary angioedema general care and long term prophylaxis
• 5. 止血の概要 overview of hemostasis

English Journal

• MT1-MMP silencing by an shRNA-armed glioma-targeted conditionally replicative adenovirus (CRAd) improves its anti-glioma efficacy in vitro and in vivo.

• Ulasov I1, Borovjagin AV2, Kaverina N3, Schroeder B4, Shah N5, Lin B5, Baryshnikov A3, Cobbs C6.
• Cancer letters.Cancer Lett.2015 Sep 1;365(2):240-50. doi: 10.1016/j.canlet.2015.06.002. Epub 2015 Jun 4.
• MMP14 (MT1-MMP) is a cell membrane-associated proteinase of the extracellular matrix, whose biological roles vary from angiogenesis to cell proliferation and survival. We recently found a direct correlation between MMP14 expression levels in brain tumors of glioma patients and the disease progressio
• PMID 26052095

• Anti-glycation and anti-angiogenic activities of 5'-methoxybiphenyl-3,4,3'-triol, a novel phytochemical component of Osteomeles schwerinae.

• Lee YM1, Kim J1, Kim CS1, Jo K1, Yoo NH2, Sohn E1, Kim JS3.
• European journal of pharmacology.Eur J Pharmacol.2015 Aug 5;760:172-8. doi: 10.1016/j.ejphar.2015.04.022. Epub 2015 Apr 25.
• Advanced glycation end products (AGEs) are involved in the development of diabetic complications such as diabetic retinopathy. 5'-methoxybiphenyl-3,4,3'-triol (referred to as K24) was isolated using bioactivity-guided fractionation of Osteomeles schwerinae C. K. Schneid. and identified as a potent A
• PMID 25917323

• The effect of AZD2171- or sTRAIL/Apo2L-loaded polylactic-co-glycolic acid microspheres on a subcutaneous glioblastoma model.

• Shivinsky A1, Bronshtein T, Haber T, Machluf M.
• Biomedical microdevices.Biomed Microdevices.2015 Aug;17(4):9969. doi: 10.1007/s10544-015-9969-2.
• Studies with AZD2171-a new anti-angiogenic inhibitor of tyrosine kinases associated with VEGF signaling-have shown great promise for treating glioblastoma. Unfortunately, AZD2171 success is limited by low permeability through the blood-brain barrier. Due to AZD2171's short half-life and high toxicit
• PMID 26044202

Japanese Journal

• Neurovascular Protective Function of Endothelial Nitric Oxide　– Recent Advances –

• Circulation Journal 80(7), 1499-1503, 2016
• NAID 130005158916

• Neurovascular Protective Function of Endothelial Nitric Oxide　– Recent Advances –

• Circulation Journal advpub(0), 2016
• NAID 130005153616

• 2) 顆粒膜細胞における細胞内信号伝達系分子の活性化機序と排卵誘発への応用(シンポジウム1(生殖) 卵巣のダイナミックな変化の神秘に迫る-臨床へのフィードバックを目指して-,第67回日本産科婦人科学会学術講演会講演要旨)

• 日本産科婦人科學會雜誌 67(10), 2152-2166, 2015-10-01
• NAID 110009989072

Related Links

• Angiogenesis inhibitor - Wikipedia, the free encyclopedia

An angiogenesis inhibitor is a substance that inhibits the growth of new blood vessels (angiogenesis). Some angiogenesis inhibitors are a normal part of the body's control, some are administered as drugs, and some come from diet.

• Angiogenesis Inhibitors - National Cancer Institute

A fact sheet that describes the process of eliminating the blood supply to tumors. Lists the cancers in which this approach is being tested.

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★リンクテーブル★

リンク元	「血管新生阻害薬」「血管新生抑制薬」「血管新生阻害剤」「血管新生抑制剤」「antiangiogenic agent」
関連記事	「angiogenic」「inhibit」「inhibitor」

「血管新生阻害薬」

　　[★]

英

angiogenic inhibitor、anti-angiogenic agent

関

血管新生阻害剤、血管新生抑制因子、血管新生抑制剤、血管新生抑制物質、血管新生抑制薬、抗血管新生薬

血管内皮増殖因子 VEGF

[show details]

血管新生阻害剤 angiogenesis : 約 77 件
血管新生阻害薬 angiogenesis : 約 83 件

薬理学

• 抗VEGF抗体

• bevacizumab

• VEGF阻害薬

• sunitinib(SU11248) 受容体キナーゼ阻害薬 -> VEGFR-1, VEGFR-2, PDGFRを阻害
• sorafenib -> B-RAF, VEGFR-1, VEGFR-2, PDGFRを阻害
• vatalanib(PTK-787)

• サリドマイドとレナリドマイド

• thalidomide
• lenalidomide

「血管新生抑制薬」

　　[★]

英

angiogenesis inhibitor、antiangiogenic agent、angiogenic inhibitor

関

血管新生阻害剤、血管新生阻害物質、血管新生抑制因子、血管新生抑制剤、血管新生阻害薬、抗血管新生薬

「血管新生阻害剤」

　　[★]

英

angiogenic inhibitor、anti-angiogenic agent

関

血管新生抑制因子、血管新生抑制剤、血管新生抑制物質、血管新生阻害薬、血管新生抑制薬、抗血管新生薬

「血管新生抑制剤」

　　[★]

英

angiogenesis inhibitor、angiogenic inhibitor

関

血管新生阻害剤、血管新生抑制因子、血管新生阻害薬、血管新生抑制薬

「antiangiogenic agent」

　　[★]

• 抗血管新生薬、血管新生抑制薬、血管新生阻害物質

関

angiogenesis inhibitor、angiogenic inhibitor、anti-angiogenic agent

「angiogenic」

　　[★]

• 血管新生の、血管形成の、血行性の、血管原性の

関

angiogenesis、angiogenetic、angioneogenesis、angioplasty、haematogenous、hematogenic、hematogenous、hematogenously、neoangiogenesis、neovascularisation、neovascularization、vascularization、vasculogenesis、vasculogenic、vasogenic

「inhibit」

　　[★]

• v.

• 抑制する、阻害する、阻止する

関

abrogate、block、depress、depression、deter、inhibition、interdict、prevent、prevention、repress、repression、restrain、restraint、suppress、suppression

　 　 　 　

「inhibitor」

　　[★]

• n.

• 阻害剤、阻害薬、抑制薬、抑制剤、(内在性物質について)インヒビター、抑制物質

関

blocker、depressant、suppressant