MPTP-induced experimental parkinsonism

• MPTP誘発実験的パーキンソニズム

関

autosomal dominant parkinsonism、autosomal recessive juvenile Parkinson disease、autosomal recessive juvenile parkinsonism、autosomal recessive parkinsonism、experimental parkinsonism、juvenile Parkinson disease、juvenile parkinsonism、parkinsonian disorder、parkinsonian syndrome、parkinsonism

WordNet

1. reason or establish by induction
2. cause to arise; "induce a crisis" (同)bring_on
3. produce electric current by electrostatic or magnetic processes (同)induct
4. cause to do; cause to act in a specified manner; "The ads induced me to buy a VCR"; "My children finally got me to buy a computer"; "My wife made me buy a new sofa" (同)stimulate, cause, have, get, make
5. cause to occur rapidly; "the infection precipitated a high fever and allergic reactions" (同)stimulate, rush, hasten
6. to conduct a test or investigation; "We are experimenting with the new drug in order to fight this disease"
7. the act of conducting a controlled test or investigation (同)experimentation
8. a venture at something new or different; "as an experiment he decided to grow a beard"
9. the testing of an idea; "it was an experiment in living"; "not all experimentation is done in laboratories" (同)experimentation
10. try something new, as in order to gain experience; "Students experiment sexually"; "The composer experimented with a new style" (同)try out
11. relating to or based on experiment; "experimental physics"
12. relying on observation or experiment; "experimental results that supported the hypothesis" (同)data-based, observational
13. of the nature of or undergoing an experiment; "an experimental drug"
14. brought about or caused; not spontaneous; "a case of steroid-induced weakness"

PrepTutorEJDIC

1. 〈人〉‘に'『勧めて』(…)『させる』 / …‘を'『引き起こす』,もたらす(cause) / 〈電気〉‘を'誘導する / …‘を'帰納する
2. (…の)『実験』,試み《+『in』(『on, with』)+『名』》 / (…の)実験をする《+『on(upon, with)』+『名』》
3. 実験の,実験に基づく: / 実験に使われる,実験用の / 実験的な,試験的な

UpToDate Contents

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• 1. パーキンソン病の診断および鑑別診断 diagnosis and differential diagnosis of parkinson disease
• 2. パーキンソン病の病因および発症機序 etiology and pathogenesis of parkinson disease
• 3. パーキンソン病の薬理学的治療 pharmacologic treatment of parkinson disease
• 4. 機能性不随意運動 functional movement disorders
• 5. パーキンソン病とパーキンソン症候群への対症療法 palliative approach to parkinson disease and parkinsonian disorders

English Journal

• Lesions of mediodorsal thalamic nucleus reverse abnormal firing of the medial prefrontal cortex neurons in parkinsonian rats.

• Fan LL, Deng B, Yan JB, Hu ZH, Ren AH, Yang DW.
• Neural regeneration research. 2019 Sep;14(9)1635-1642.
• The dysfunction of the medial prefrontal cortex is associated with affective disorders and non-motor features in Parkinson's disease. However, the exact role of the mediodorsal thalamic nucleus in the function of the prefrontal cortex remains unclear. To study the possible effects of the mediodorsal
• PMID 31089064

• Olfaction in female Wistar rats is influenced by dopaminergic periglomerular neurons after nigral and bulbar lesions.

• Rodrigues LS, Noseda ACD, Targa ADS, Aurich MF, Lima MMS.
• Behavioural pharmacology. 2019 Jun;30(4)343-350.
• Hyposmia is found in Parkinsonian patients decades before the onset of motor disorders. The same occurs with sleep disorders, especially infuencing rapid eye movement (REM) sleep, which affect a large percentage of people who have Parkinson's disease. These two disturbances presumably are closely re
• PMID 30222597

• Focus on the pedunculopontine nucleus. Consensus review from the May 2018 brainstem society meeting in Washington, DC, USA.

• Garcia-Rill E, Saper CB, Rye DB, Kofler M, Nonnekes J, Lozano A, Valls-Solé J, Hallett M.
• Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2019 Jun;130(6)925-940.
• The pedunculopontine nucleus (PPN) is located in the mesopontine tegmentum and is best delimited by a group of large cholinergic neurons adjacent to the decussation of the superior cerebellar peduncle. This part of the brain, populated by many other neuronal groups, is a crossroads for many importan
• PMID 30981899

Japanese Journal

• NEUROPROTECTIVE ACTION OF SINGLE DOSE DEPRENYL AGAINST MPTP-INDUCED PARKINSONISM IN COMMON MARMOSETS

• ANDO Kiyoshi,ISHII Hajime,TANIOKA Yoshikuni,MAEDA Jun,SUHARA Tetsuya
• 日本神経精神薬理学雑誌 = Japanese journal of psychopharmacology 25(6), 286, 2005-12-25
• NAID 10016942879

Related Links

• Parkinsonism induced by MPTP as an experimental model of ...

Remote Second Opinion Obtain a remote medical opinion for your clinical case, from your home and without travelling, with the quality and support of the Clínica ... Parkinsonism induced by MPTP as an experimental model of ...

• MPTP-induced Parkinsonism - an overview | ScienceDirect Topics

The history of MPTP-induced parkinsonism in young adults who inadvertently injected themselves with this compound is well known. MPTP is a protoxicant that, after crossing the blood-brain barrier, is metabolized by glial MAO-B to ...

• mptp induced experimental : definition of mptp induced ...

MPTP-Induced Experimental Parkinsonism (n.) 1. A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally ...

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★リンクテーブル★

リンク元	「MPTP誘発実験的パーキンソニズム」「autosomal recessive juvenile parkinsonism」「autosomal recessive juvenile Parkinson disease」「juvenile Parkinson disease」「autosomal recessive parkinsonism」
関連記事	「experimental parkinsonism」「induce」「experimental」「MPTP」「MP」

「MPTP誘発実験的パーキンソニズム」

　　[★]

英

MPTP-induced experimental parkinsonism

関

パーキンソニズム、パーキンソン症候群、若年性パーキンソニズム、常染色体劣性若年性パーキンソニズム、若年性パーキンソン病、常染色体優性パーキソニズム、実験的パーキソニズム、常染色体劣性若年性パーキンソン病、パーキンソン病様症状、常染色体劣性遺伝パーキンソニズム

「autosomal recessive juvenile parkinsonism」

　　[★]

常染色体劣性若年性パーキンソニズム、常染色体劣性遺伝性若年性パーキンソニズム

関

autosomal dominant parkinsonism、autosomal recessive juvenile Parkinson disease、autosomal recessive parkinsonism、experimental parkinsonism、juvenile Parkinson disease、juvenile parkinsonism、MPTP-induced experimental parkinsonism、parkinsonian disorder、parkinsonian syndrome、parkinsonism

「autosomal recessive juvenile Parkinson disease」

　　[★]

常染色体劣性若年性パーキンソン病、常染色体劣性若年性Parkinson病

関

autosomal dominant parkinsonism、autosomal recessive juvenile parkinsonism、autosomal recessive parkinsonism、experimental parkinsonism、juvenile Parkinson disease、juvenile parkinsonism、MPTP-induced experimental parkinsonism、parkinsonian disorder、parkinsonian syndrome、parkinsonism

「juvenile Parkinson disease」

　　[★]

若年性パーキンソン病、若年性Parkinson病

関

autosomal dominant parkinsonism、autosomal recessive juvenile Parkinson disease、autosomal recessive juvenile parkinsonism、autosomal recessive parkinsonism、experimental parkinsonism、juvenile parkinsonism、MPTP-induced experimental parkinsonism、parkinsonian disorder、parkinsonian syndrome、parkinsonism

「autosomal recessive parkinsonism」

　　[★]

常染色体劣性遺伝パーキンソニズム

関

autosomal dominant parkinsonism、autosomal recessive juvenile Parkinson disease、autosomal recessive juvenile parkinsonism、experimental parkinsonism、juvenile Parkinson disease、juvenile parkinsonism、MPTP-induced experimental parkinsonism、parkinsonian disorder、parkinsonian syndrome、parkinsonism

「experimental parkinsonism」

　　[★]

実験的パーキソニズム

関

autosomal dominant parkinsonism、autosomal recessive juvenile Parkinson disease、autosomal recessive juvenile parkinsonism、autosomal recessive parkinsonism、juvenile Parkinson disease、juvenile parkinsonism、MPTP-induced experimental parkinsonism、parkinsonian disorder、parkinsonian syndrome、parkinsonism

「induce」

　　[★]

• v.

• 誘発する、誘導する、誘起する、導入する、引き起こす

関

cause、challenge、derivation、elicit、elicitation、evocation、evoke、guidance、induction、inductive、introduce、introduction、precipitate、provocation、provoke、spark

　 　 　 　 　 　

「experimental」

　　[★]

• adj.

• 実験の、実験的な、実験用の、実験上の、経験的な

関

a priori、empiric、empirical、empirically、experiment、experimentally

　 　 　 　

「MPTP」

　　[★] メチルフェニルテトラヒドロピリジン

同

N-methyl-4-phenyl- 1 ,2,3 ,6-tetrahy- ▲ dropyridine

同

N-methyl-4-phenyl- 1 ,2,3 ,6-tetrahy- ▲ dropyridine

「MP」

　　[★]

• ムコタンパク ムコタンパク質 mucoprotein
• 中手指節 metacarpophalangeal　→中手指節関節 MP関節
• 固有筋層 muscularis propria