WordNet

the 9th letter of the Roman alphabet (同)i
any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis (同)peptidase, proteinase, proteolytic_enzyme
any tropical African shrub of the genus Protea having alternate rigid leaves and dense colorful flower heads resembling cones

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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/11/30 22:30:21」(JST)

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1. IgA腎症の治療および予後 treatment and prognosis of iga nephropathy
2. IgA腎症の病因 pathogenesis of iga nephropathy
3. Clinical presentation and diagnosis of IgA nephropathy
4. IgGの構造および生物学的機能 structure and biologic functions of iga
5. 選択的IgA欠損症：臨床症状、病態生理、および診断 selective iga deficiency clinical manifestations pathophysiology and diagnosis

Bacterial IgA protease-mediated degradation of agIgA1 and agIgA1 immune complexes as a potential therapy for IgA Nephropathy.

Wang L1,2, Li X3, Shen H4, Mao N5, Wang H1, Cui L6, Cheng Y7, Fan J2,3,8.
Scientific reports.Sci Rep.2016 Aug 3;6:30964. doi: 10.1038/srep30964.
Mesangial deposition of aberrantly glycosylated IgA1 (agIgA1) and its immune complexes is a key pathogenic mechanism of IgA nephropathy (IgAN). However, treatment of IgAN remains ineffective. We report here that bacteria-derived IgA proteases are capable of degrading these pathogenic agIgA1 and deri
PMID 27485391

Fitness Cost of Rifampin Resistance in Neisseria meningitidis: In Vitro Study of Mechanisms Associated with rpoB H553Y Mutation.

Colicchio R1, Pagliuca C2, Pastore G3, Cicatiello AG4, Pagliarulo C3, Talà A5, Scaglione E4, Sammartino JC4, Bucci C5, Alifano P6, Salvatore P7.
Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2015 Dec;59(12):7637-49. doi: 10.1128/AAC.01746-15. Epub 2015 Sep 28.
Rifampin chemoprophylaxis against Neisseria meningitidis infections led to the onset of rifampin resistance in clinical isolates harboring point mutations in the rpoB gene, coding for the RNA polymerase β chain. These resistant strains are rare in medical practice, suggesting their decreased fitnes
PMID 26416867

Expression of IgA Proteases by Haemophilus influenzae in the Respiratory Tract of Adults With Chronic Obstructive Pulmonary Disease.

Murphy TF1, Kirkham C2, Jones MM3, Sethi S4, Kong Y5, Pettigrew MM6.
The Journal of infectious diseases.J Infect Dis.2015 Dec 1;212(11):1798-805. doi: 10.1093/infdis/jiv299. Epub 2015 May 20.
BACKGROUND: Immunoglobulin (Ig)A proteases of Haemophilus influenzae are highly specific endopeptidases that cleave the hinge region of human IgA1 and also mediate invasion and trafficking in human respiratory epithelial cells, facilitating persistence of H. influenzae. Little is known about the exp
PMID 25995193

小野孝彦
YAKUGAKU ZASSHI 132(4), 449-453, 2012
… Factor Xa activates various cell types through protease-activated receptor 2 (PAR2). … The factor Xa inhibitor danaparoid ameliorated proteinuria, cellular proliferation, and fibrin deposition in lipopolysaccharide (LPS)-triggered activation of High IgA (HIGA) strain of ddY mice. …
NAID 130001872047

FUJITA Kiyotaka,KAMEKO Fumiko,KATO Yoko,FUKUSHIMA Mana,OKUMURA Nobuo,TERASAWA Fumiko,SUGANO Mitsutoshi,YAMAUCHI Kazuyoshi,SATO Hirohisa,KAMEKO Mitsuaki,SAKURABAYASHI Ikunosuke
Journal of electrophoresis 50(2), 19-23, 2006-06-01
… We recently demonstrated glycation of monoclonal IgA and the presence of IgA-albumin complexes, but the mechanism of IgA-albumin complex formation was not clear. … We isolated the IgA-albumin complexes from 5 IgA type M-proteinemia patients' sera. …
NAID 10018150539