Gタンパク質共役受容体キナーゼ5
- 関
- GRK5
WordNet
- link together; "can we couple these proposals?" (同)couple on, couple up
- two items of the same kind (同)pair, twosome, twain, brace, span, yoke, couplet, distich, duo, duet, dyad, duad
- a small indefinite number; "hes coming for a couple of days"
- a pair of people who live together; "a married couple from Chicago" (同)mates, match
- a pair who associate with one another; "the engaged couple"; "an inseparable twosome" (同)twosome, duo, duet
- (physics) something joined by two equal and opposite forces that act along parallel lines
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
- a unit of force equal to the force exerted by gravity; used to indicate the force to which a body is subjected when it is accelerated (同)gee, g-force
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
PrepTutorEJDIC
- (同種類の物が)『2個』《+『of』+『名』》 / 『夫婦』,男女一組 / 《話》(…の)いくらか,少数《+『of』+『名』》 / …'を'『つなぎ合わせる』;(…に)…'を'連結する《+『名』+『to』(『with』)+『名』》 / …'を'(…と)関連づける《+『名』+『with』(『to』)+『名』》 / …'を'結婚させる,〈動物〉'を'つがわせる / 〈動物〉交尾する
- 蛋白(たんばく)質
- =sense organ / 受信装置
UpToDate Contents
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English Journal
- Interplay between Sumoylation and Phosphorylation for Protection against α-Synuclein Inclusions.
- Shahpasandzadeh H1, Popova B1, Kleinknecht A1, Fraser PE2, Outeiro TF3, Braus GH4.
- The Journal of biological chemistry.J Biol Chem.2014 Nov 7;289(45):31224-40. doi: 10.1074/jbc.M114.559237. Epub 2014 Sep 17.
- Parkinson disease is associated with the progressive loss of dopaminergic neurons from the substantia nigra. The pathological hallmark of the disease is the accumulation of intracytoplasmic inclusions known as Lewy bodies that consist mainly of post-translationally modified forms of α-synuclein. Wh
- PMID 25231978
- Identification and characterization of amlexanox as a g protein-coupled receptor kinase 5 inhibitor.
- Homan KT1, Wu E1, Cannavo A2, Koch WJ2, Tesmer JJ3.
- Molecules (Basel, Switzerland).Molecules.2014 Oct 22;19(10):16937-49. doi: 10.3390/molecules191016937.
- G protein-coupled receptor kinases (GRKs) have been implicated in human diseases ranging from heart failure to diabetes. Previous studies have identified several compounds that selectively inhibit GRK2, such as paroxetine and balanol. Far fewer selective inhibitors have been reported for GRK5, a tar
- PMID 25340299
- G Protein-Coupled Receptor Kinase 5 Gene Polymorphisms Are Associated with Postoperative Atrial Fibrillation Following Coronary Artery Bypass Graft Surgery in Patients Receiving Beta-Blockers.
- Kertai MD1, Li YW2, Li YJ3, Shah SH4, Kraus WE4, Fontes ML5, Stafford-Smith M5, Newman MF5, Podgoreanu MV5, Mathew JP5.
- Circulation. Cardiovascular genetics.Circ Cardiovasc Genet.2014 Jul 21. pii: CIRCGENETICS.113.000451. [Epub ahead of print]
- BACKGROUND: -We hypothesized that genetic variations in the adrenergic signaling pathway and cytochrome P450 (CYP) 2D6 enzyme are associated with new-onset atrial fibrillation (AF) in patients who underwent coronary artery bypass graft (CABG) surgery and were treated with perioperative beta-blocker
- PMID 25049040
Japanese Journal
- 生体内で死んだ細胞の除去を促進する新たな分子の同定 : アポトーシス細胞の貪食におけるGRK6の役割 (特集 Gタンパク質共役型受容体の活性制御にかかわる分子群の新展開)
- 仲矢 道雄,黒瀬 等
- 日本薬理学雑誌 = Folia pharmacologica Japonica : くすりとからだ : ファーマコロジカ 145(1), 14-20, 2015-01
- NAID 40020312392
- GPCRキナーゼのニトロシル化による制御と創薬戦略 (特集 Gタンパク質共役型受容体の活性制御にかかわる分子群の新展開)
- 飯利 太朗,槙田 紀子
- 日本薬理学雑誌 = Folia pharmacologica Japonica : くすりとからだ : ファーマコロジカ 145(1), 10-13, 2015-01
- NAID 40020312366
- 津田 正明
- 薬学雑誌. 乙号 135(4), 597-617, 2015
- … Particularly focusing on the transcription regulation of the brain-derived neurotrophic factor (BDNF) gene (Bdnf), I found that the interaction of the cAMP response element-binding protein (CREB) with the CRE sequence is important for the activity-dependent activation of the Bdnf promoter. …
- NAID 130005060826
Related Links
- 1. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):308-16. doi: 10.1161/ATVBAHA.111.239608. Epub 2011 Nov 17. G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7 ...
- Serine/threonine kinase that phosphorylates preferentially the activated forms of a variety of G-protein-coupled receptors (GPCRs). Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization ...
★リンクテーブル★
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- 関
- G-protein-coupled receptor kinase 5
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- 英
- G-protein-coupled receptor kinase 5、GRK5
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- 関
- associate、association、bind、binding、bond、bonding、combine、conjoin、conjugate、conjugated、conjugation、conjunction、connect、connection、coupling、dock、doublet、engage、engagement、family characteristics、generation、household、join、ligate、linkage、pair、symphysial、union
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キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase
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[★]
- 同
- G proteins
- 同
- G proteins
[★]
- 同
- ガドリニウム造影MRI